CA1170001A - Methode de maintien de la porosite des materiaux poreux - Google Patents

Methode de maintien de la porosite des materiaux poreux

Info

Publication number: CA1170001A
Authority: CA; Canada
Prior art keywords: highly porous; porous foam; porosity; collapsible; dimensionally
Prior art date: 1980-07-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA000381746A

Other languages

English (en)

Inventor

Ioannis V. Yannas

John F. Burke

Peter J. Stasikelis

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Massachusetts Institute of Technology

Original Assignee

Massachusetts Institute of Technology

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-07-17

Filing date

1981-07-15

Publication date

1984-07-03

1981-07-15 Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology

1984-07-03 Application granted granted Critical

1984-07-03 Publication of CA1170001A publication Critical patent/CA1170001A/fr

Status Expired legal-status Critical Current

Links

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239000011148 porous material Substances 0.000 title description 23
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108090000623 proteins and genes Proteins 0.000 claims abstract description 21
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239000007788 liquid Substances 0.000 claims abstract description 15
239000003431 cross linking reagent Substances 0.000 claims abstract description 8
238000010382 chemical cross-linking Methods 0.000 claims abstract description 7
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KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
102000009027 Albumins Human genes 0.000 description 1
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239000004722 Artley Substances 0.000 description 1
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102000008946 Fibrinogen Human genes 0.000 description 1
108010049003 Fibrinogen Proteins 0.000 description 1
BRDWIEOJOWJCLU-LTGWCKQJSA-N GS-441524 Chemical compound C=1C=C2C(N)=NC=NN2C=1[C@]1(C#N)O[C@H](CO)[C@@H](O)[C@H]1O BRDWIEOJOWJCLU-LTGWCKQJSA-N 0.000 description 1
108010010803 Gelatin Proteins 0.000 description 1
229920002971 Heparan sulfate Polymers 0.000 description 1
HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
229920000288 Keratan sulfate Polymers 0.000 description 1
229920005830 Polyurethane Foam Polymers 0.000 description 1
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
108010073771 Soybean Proteins Proteins 0.000 description 1
230000002378 acidificating effect Effects 0.000 description 1
239000000853 adhesive Substances 0.000 description 1
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XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
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KXKPYJOVDUMHGS-OSRGNVMNSA-N chondroitin sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](OS(O)(=O)=O)[C@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O1 KXKPYJOVDUMHGS-OSRGNVMNSA-N 0.000 description 1
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AVJBPWGFOQAPRH-FWMKGIEWSA-L dermatan sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](C([O-])=O)O1 AVJBPWGFOQAPRH-FWMKGIEWSA-L 0.000 description 1
229940051593 dermatan sulfate Drugs 0.000 description 1
210000004207 dermis Anatomy 0.000 description 1
125000005442 diisocyanate group Chemical group 0.000 description 1
230000000694 effects Effects 0.000 description 1
210000002615 epidermis Anatomy 0.000 description 1
150000002148 esters Chemical class 0.000 description 1
239000004744 fabric Substances 0.000 description 1
229940012952 fibrinogen Drugs 0.000 description 1
239000012530 fluid Substances 0.000 description 1
230000004907 flux Effects 0.000 description 1
229920000159 gelatin Polymers 0.000 description 1
239000008273 gelatin Substances 0.000 description 1
235000019322 gelatine Nutrition 0.000 description 1
235000011852 gelatine desserts Nutrition 0.000 description 1
230000036541 health Effects 0.000 description 1
238000010438 heat treatment Methods 0.000 description 1
229920000669 heparin Polymers 0.000 description 1
229960002897 heparin Drugs 0.000 description 1
229920002674 hyaluronan Polymers 0.000 description 1
229960003160 hyaluronic acid Drugs 0.000 description 1
230000008595 infiltration Effects 0.000 description 1
238000001764 infiltration Methods 0.000 description 1
238000009413 insulation Methods 0.000 description 1
KXCLCNHUUKTANI-RBIYJLQWSA-N keratan Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@H](COS(O)(=O)=O)O[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@H](O[C@@H](O[C@H]3[C@H]([C@@H](COS(O)(=O)=O)O[C@@H](O)[C@@H]3O)O)[C@H](NC(C)=O)[C@H]2O)COS(O)(=O)=O)O[C@H](COS(O)(=O)=O)[C@@H]1O KXCLCNHUUKTANI-RBIYJLQWSA-N 0.000 description 1
239000002649 leather substitute Substances 0.000 description 1
239000004571 lime Substances 0.000 description 1
239000002609 medium Substances 0.000 description 1
238000000465 moulding Methods 0.000 description 1
231100000252 nontoxic Toxicity 0.000 description 1
230000003000 nontoxic effect Effects 0.000 description 1
229920000058 polyacrylate Polymers 0.000 description 1
229920000642 polymer Polymers 0.000 description 1
229920000193 polymethacrylate Polymers 0.000 description 1
229920001282 polysaccharide Polymers 0.000 description 1
239000005017 polysaccharide Substances 0.000 description 1
239000011496 polyurethane foam Substances 0.000 description 1
235000004252 protein component Nutrition 0.000 description 1
230000005855 radiation Effects 0.000 description 1
238000004626 scanning electron microscopy Methods 0.000 description 1
229920000260 silastic Polymers 0.000 description 1
229920002050 silicone resin Polymers 0.000 description 1
229920002379 silicone rubber Polymers 0.000 description 1
239000004945 silicone rubber Substances 0.000 description 1
239000000243 solution Substances 0.000 description 1
235000019710 soybean protein Nutrition 0.000 description 1
238000003860 storage Methods 0.000 description 1
239000000126 substance Substances 0.000 description 1
230000008961 swelling Effects 0.000 description 1
230000008364 tissue synthesis Effects 0.000 description 1
239000003440 toxic substance Substances 0.000 description 1

Landscapes

Materials For Medical Uses (AREA)
Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)

CA000381746A 1980-07-17 1981-07-15 Methode de maintien de la porosite des materiaux poreux Expired CA1170001A (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US16989780A	1980-07-17	1980-07-17
US169,897		1980-07-17

Publications (1)

Publication Number	Publication Date
CA1170001A true CA1170001A (fr)	1984-07-03

Family

ID=22617666

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA000381746A Expired CA1170001A (fr)	1980-07-17	1981-07-15	Methode de maintien de la porosite des materiaux poreux

Country Status (1)

Country	Link
CA (1)	CA1170001A (fr)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4861714A (en) *	1985-04-04	1989-08-29	Verax Corporation	Weighted collagen microsponge for immobilizing bioactive material
US4880429A (en) *	1987-07-20	1989-11-14	Stone Kevin R	Prosthetic meniscus
US5007934A (en) *	1987-07-20	1991-04-16	Regen Corporation	Prosthetic meniscus
EP0440198A3 (en) *	1990-01-31	1992-01-15	Gunze Limited	Process for preparation of dried collagen sponge
US5100783A (en) *	1985-05-10	1992-03-31	Verax Corporation	Weighted microsponge for immobilizing bioactive material
US5158574A (en) *	1987-07-20	1992-10-27	Regen Corporation	Prosthetic meniscus
US5263984A (en) *	1987-07-20	1993-11-23	Regen Biologics, Inc.	Prosthetic ligaments
US5306311A (en) *	1987-07-20	1994-04-26	Regen Corporation	Prosthetic articular cartilage
US5681353A (en) *	1987-07-20	1997-10-28	Regen Biologics, Inc.	Meniscal augmentation device
US5735902A (en) *	1987-07-20	1998-04-07	Regen Biologics, Inc.	Hand implant device
CN111067665A (zh) *	2019-12-24	2020-04-28	深圳齐康医疗器械有限公司	多孔人工真皮及其制备方法和模具

1981
- 1981-07-15 CA CA000381746A patent/CA1170001A/fr not_active Expired

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4861714A (en) *	1985-04-04	1989-08-29	Verax Corporation	Weighted collagen microsponge for immobilizing bioactive material
US5100783A (en) *	1985-05-10	1992-03-31	Verax Corporation	Weighted microsponge for immobilizing bioactive material
US5681353A (en) *	1987-07-20	1997-10-28	Regen Biologics, Inc.	Meniscal augmentation device
US5007934A (en) *	1987-07-20	1991-04-16	Regen Corporation	Prosthetic meniscus
US5158574A (en) *	1987-07-20	1992-10-27	Regen Corporation	Prosthetic meniscus
US5263984A (en) *	1987-07-20	1993-11-23	Regen Biologics, Inc.	Prosthetic ligaments
US5306311A (en) *	1987-07-20	1994-04-26	Regen Corporation	Prosthetic articular cartilage
US5624463A (en) *	1987-07-20	1997-04-29	Regen Biologics, Inc.	Prosthetic articular cartilage
US4880429A (en) *	1987-07-20	1989-11-14	Stone Kevin R	Prosthetic meniscus
US5735902A (en) *	1987-07-20	1998-04-07	Regen Biologics, Inc.	Hand implant device
US5735903A (en) *	1987-07-20	1998-04-07	Li; Shu-Tung	Meniscal augmentation device
US6042610A (en) *	1987-07-20	2000-03-28	Regen Biologics, Inc.	Meniscal augmentation device
EP0440198A3 (en) *	1990-01-31	1992-01-15	Gunze Limited	Process for preparation of dried collagen sponge
CN111067665A (zh) *	2019-12-24	2020-04-28	深圳齐康医疗器械有限公司	多孔人工真皮及其制备方法和模具

Legal Events

Date	Code	Title	Description
2001-07-03	MKEX	Expiry

Publication	Publication Date	Title
US4522753A (en)	1985-06-11	Method for preserving porosity in porous materials
US5632776A (en)	1997-05-27	Implantation materials
Chvapil et al.	1969	Some chemical and biological characteristics of a new collagen–polymer compound material
US4412947A (en)	1983-11-01	Collagen sponge
US5098779A (en)	1992-03-24	Carvable implant material
US4787900A (en)	1988-11-29	Process for forming multilayer bioreplaceable blood vessel prosthesis
US6015844A (en)	2000-01-18	Composite surgical material
Yannas	1992	Tissue regeneration by use of collagen-glycosaminoglycan copolymers
CA1170001A (fr)	1984-07-03	Methode de maintien de la porosite des materiaux poreux
EP0091952B1 (fr)	1986-06-04	Technique d'ensemencement cellulaire comprenant l'utilisation de treillis fibreux
US5350583A (en)	1994-09-27	Cell-penetrable medical material and artificial skin
US4060081A (en)	1977-11-29	Multilayer membrane useful as synthetic skin
Yannas	1990	Biologically active analogues of the extracellular matrix: artificial skin and nerves
US5869080A (en)	1999-02-09	Absorbable implant materials having controlled porosity
EP0403650B1 (fr)	1994-05-25	Substance medicale dans laquelle les cellules peuvent penetrer et peau artificielle
US6001895A (en)	1999-12-14	Composite surgical material
US6500464B2 (en)	2002-12-31	Bilayered collagen construct
CA2334664A1 (fr)	1999-12-16	Materiau collagenique et procede de production
EP0512122A1 (fr)	1992-11-11	Materiau pour implants
EP1981558A2 (fr)	2008-10-22	Produit de réparation méningée et durale suturable comprenant une matrice de collagène
EP0742020A2 (fr)	1996-11-13	Prothèse contenant des matériaux biorésorbables insolubilisés sans réactifs chimiques et son procédé de préparation
EP0107711A4 (fr)	1985-10-24	Prothese multi-couches bioremplacable de vaisseaux sanguins.
EP0636377B1 (fr)	2002-02-20	Utilisation d'un matériau composite chirurgical
JPH0242656B2 (fr)	1990-09-25
EP0411124A1 (fr)	1991-02-06	Substance medicale dans laquelle les cellules peuvent penetrer et peau artificielle