CA1178547A - Methode pour la production d'une levure contenant du chrome - Google Patents

Methode pour la production d'une levure contenant du chrome

Info

Publication number: CA1178547A
Authority: CA; Canada
Prior art keywords: yeast; chromium; yeast cells; growth; period
Prior art date: 1982-05-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA000403593A

Other languages

English (en)

Inventor

Lawrence E. Skogerson

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sensient Technologies Corp

Original Assignee

Universal Foods Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-05-21

Filing date

1982-05-21

Publication date

1984-11-27

1982-05-21 Application filed by Universal Foods Corp filed Critical Universal Foods Corp

1982-05-21 Priority to CA000403593A priority Critical patent/CA1178547A/fr

1984-11-27 Application granted granted Critical

1984-11-27 Publication of CA1178547A publication Critical patent/CA1178547A/fr

Status Expired legal-status Critical Current

Links

240000004808 Saccharomyces cerevisiae Species 0.000 title claims abstract description 126
239000011651 chromium Substances 0.000 title claims abstract description 87
VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 title claims abstract description 83
229910052804 chromium Inorganic materials 0.000 title claims abstract description 83
238000000034 method Methods 0.000 title claims abstract description 28
238000004519 manufacturing process Methods 0.000 title description 5
210000005253 yeast cell Anatomy 0.000 claims abstract description 50
230000003834 intracellular effect Effects 0.000 claims abstract description 36
230000012010 growth Effects 0.000 claims abstract description 31
150000001844 chromium Chemical class 0.000 claims abstract description 26
229910001430 chromium ion Inorganic materials 0.000 claims abstract description 24
238000010521 absorption reaction Methods 0.000 claims abstract description 13
239000007900 aqueous suspension Substances 0.000 claims abstract description 12
235000015097 nutrients Nutrition 0.000 claims abstract description 8
231100000252 nontoxic Toxicity 0.000 claims abstract description 7
230000003000 nontoxic effect Effects 0.000 claims abstract description 7
238000001035 drying Methods 0.000 claims abstract description 6
238000005406 washing Methods 0.000 claims abstract description 6
235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims description 122
239000007787 solid Substances 0.000 claims description 29
238000002203 pretreatment Methods 0.000 claims description 26
235000013305 food Nutrition 0.000 claims description 9
239000002609 medium Substances 0.000 claims description 5
239000012736 aqueous medium Substances 0.000 claims description 4
230000002401 inhibitory effect Effects 0.000 claims description 3
239000001963 growth medium Substances 0.000 claims description 2
239000000725 suspension Substances 0.000 claims description 2
239000000047 product Substances 0.000 abstract description 15
235000005911 diet Nutrition 0.000 abstract description 13
230000000378 dietary effect Effects 0.000 abstract description 4
239000013589 supplement Substances 0.000 abstract description 3
230000002378 acidificating effect Effects 0.000 abstract description 2
238000011084 recovery Methods 0.000 abstract 1
235000012721 chromium Nutrition 0.000 description 70
229940107218 chromium Drugs 0.000 description 70
230000009102 absorption Effects 0.000 description 11
230000037213 diet Effects 0.000 description 9
230000004151 fermentation Effects 0.000 description 8
238000000855 fermentation Methods 0.000 description 8
WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 7
230000003698 anagen phase Effects 0.000 description 7
238000002474 experimental method Methods 0.000 description 7
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 5
230000000694 effects Effects 0.000 description 5
239000008103 glucose Substances 0.000 description 5
235000013379 molasses Nutrition 0.000 description 5
NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 4
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 4
230000007812 deficiency Effects 0.000 description 4
235000015872 dietary supplement Nutrition 0.000 description 4
230000001965 increasing effect Effects 0.000 description 4
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 4
150000003839 salts Chemical class 0.000 description 4
QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 3
208000002705 Glucose Intolerance Diseases 0.000 description 3
230000006735 deficit Effects 0.000 description 3
239000001103 potassium chloride Substances 0.000 description 3
235000011164 potassium chloride Nutrition 0.000 description 3
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
206010018429 Glucose tolerance impaired Diseases 0.000 description 2
102000004877 Insulin Human genes 0.000 description 2
108090001061 Insulin Proteins 0.000 description 2
CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
241001465754 Metazoa Species 0.000 description 2
241000582914 Saccharomyces uvarum Species 0.000 description 2
241000006364 Torula Species 0.000 description 2
239000002253 acid Substances 0.000 description 2
229910000147 aluminium phosphate Inorganic materials 0.000 description 2
229960000359 chromic chloride Drugs 0.000 description 2
150000001845 chromium compounds Chemical class 0.000 description 2
LJAOOBNHPFKCDR-UHFFFAOYSA-K chromium(3+) trichloride hexahydrate Chemical compound O.O.O.O.O.O.[Cl-].[Cl-].[Cl-].[Cr+3] LJAOOBNHPFKCDR-UHFFFAOYSA-K 0.000 description 2
230000003247 decreasing effect Effects 0.000 description 2
230000002950 deficient Effects 0.000 description 2
229940125396 insulin Drugs 0.000 description 2
230000000153 supplemental effect Effects 0.000 description 2
229910019670 (NH4)H2PO4 Inorganic materials 0.000 description 1
QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 1
CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 description 1
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
241001600451 Chromis Species 0.000 description 1
241000700159 Rattus Species 0.000 description 1
235000003534 Saccharomyces carlsbergensis Nutrition 0.000 description 1
241001123227 Saccharomyces pastorianus Species 0.000 description 1
239000000654 additive Substances 0.000 description 1
230000000996 additive effect Effects 0.000 description 1
238000013019 agitation Methods 0.000 description 1
229910021529 ammonia Inorganic materials 0.000 description 1
LFVGISIMTYGQHF-UHFFFAOYSA-N ammonium dihydrogen phosphate Chemical compound [NH4+].OP(O)([O-])=O LFVGISIMTYGQHF-UHFFFAOYSA-N 0.000 description 1
229910000387 ammonium dihydrogen phosphate Inorganic materials 0.000 description 1
239000000908 ammonium hydroxide Substances 0.000 description 1
230000004071 biological effect Effects 0.000 description 1
239000008280 blood Substances 0.000 description 1
210000004369 blood Anatomy 0.000 description 1
150000001720 carbohydrates Chemical class 0.000 description 1
229910052799 carbon Inorganic materials 0.000 description 1
238000005119 centrifugation Methods 0.000 description 1
235000007831 chromium(III) chloride Nutrition 0.000 description 1
239000011636 chromium(III) chloride Substances 0.000 description 1
239000006071 cream Substances 0.000 description 1
230000001419 dependent effect Effects 0.000 description 1
206010012601 diabetes mellitus Diseases 0.000 description 1
238000009826 distribution Methods 0.000 description 1
230000029142 excretion Effects 0.000 description 1
BHEPBYXIRTUNPN-UHFFFAOYSA-N hydridophosphorus(.) (triplet) Chemical compound [PH] BHEPBYXIRTUNPN-UHFFFAOYSA-N 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 description 1
230000001939 inductive effect Effects 0.000 description 1
230000005764 inhibitory process Effects 0.000 description 1
230000031891 intestinal absorption Effects 0.000 description 1
238000001990 intravenous administration Methods 0.000 description 1
229910052943 magnesium sulfate Inorganic materials 0.000 description 1
WRUGWIBCXHJTDG-UHFFFAOYSA-L magnesium sulfate heptahydrate Chemical compound O.O.O.O.O.O.O.[Mg+2].[O-]S([O-])(=O)=O WRUGWIBCXHJTDG-UHFFFAOYSA-L 0.000 description 1
235000019341 magnesium sulphate Nutrition 0.000 description 1
230000004060 metabolic process Effects 0.000 description 1
235000019837 monoammonium phosphate Nutrition 0.000 description 1
229930014626 natural product Natural products 0.000 description 1
150000002823 nitrates Chemical class 0.000 description 1
229910052757 nitrogen Inorganic materials 0.000 description 1
235000016709 nutrition Nutrition 0.000 description 1
230000001151 other effect Effects 0.000 description 1
238000004806 packaging method and process Methods 0.000 description 1
230000002093 peripheral effect Effects 0.000 description 1
239000000843 powder Substances 0.000 description 1
201000009104 prediabetes syndrome Diseases 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
230000000750 progressive effect Effects 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
239000008279 sol Substances 0.000 description 1
230000002311 subsequent effect Effects 0.000 description 1
239000000126 substance Substances 0.000 description 1
230000001502 supplementing effect Effects 0.000 description 1
235000013619 trace mineral Nutrition 0.000 description 1
239000011573 trace mineral Substances 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1

Landscapes

Coloring Foods And Improving Nutritive Qualities (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

CA000403593A 1982-05-21 1982-05-21 Methode pour la production d'une levure contenant du chrome Expired CA1178547A (fr)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
CA000403593A CA1178547A (fr)	1982-05-21	1982-05-21	Methode pour la production d'une levure contenant du chrome

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CA000403593A CA1178547A (fr)	1982-05-21	1982-05-21	Methode pour la production d'une levure contenant du chrome

Publications (1)

Publication Number	Publication Date
CA1178547A true CA1178547A (fr)	1984-11-27

Family

ID=4122843

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA000403593A Expired CA1178547A (fr)	1982-05-21	1982-05-21	Methode pour la production d'une levure contenant du chrome

Country Status (1)

Country	Link
CA (1)	CA1178547A (fr)

1982
- 1982-05-21 CA CA000403593A patent/CA1178547A/fr not_active Expired

Legal Events

Date	Code	Title	Description
2001-11-28	MKEC	Expiry (correction)
2002-05-21	MKEX	Expiry

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