CA1206092A - Detection immunohistochimique des anticorps antinucleaires au moyen de la glucose oxydase - Google Patents

Detection immunohistochimique des anticorps antinucleaires au moyen de la glucose oxydase

Info

Publication number: CA1206092A
Authority: CA; Canada
Prior art keywords: antigen source; contacting; source; glucose oxidase; glucose
Prior art date: 1981-08-31
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA000410409A

Other languages

English (en)

Inventor

Tara Rathlev

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

ICL SCIENTIFIC

Original Assignee

ICL SCIENTIFIC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-08-31

Filing date

1982-08-30

Publication date

1986-06-17

1982-08-30 Application filed by ICL SCIENTIFIC filed Critical ICL SCIENTIFIC

1986-06-17 Application granted granted Critical

1986-06-17 Publication of CA1206092A publication Critical patent/CA1206092A/fr

Status Expired legal-status Critical Current

Links

230000003460 anti-nuclear Effects 0.000 title claims abstract description 14
108010015776 Glucose oxidase Proteins 0.000 title claims abstract description 7
239000004366 Glucose oxidase Substances 0.000 title claims abstract description 7
229940116332 glucose oxidase Drugs 0.000 title claims abstract description 7
235000019420 glucose oxidase Nutrition 0.000 title claims abstract description 7
238000013115 immunohistochemical detection Methods 0.000 title abstract description 4
239000000427 antigen Substances 0.000 claims abstract description 20
102000036639 antigens Human genes 0.000 claims abstract description 20
108091007433 antigens Proteins 0.000 claims abstract description 20
238000000034 method Methods 0.000 claims abstract description 19
239000000203 mixture Substances 0.000 claims abstract description 9
210000002966 serum Anatomy 0.000 claims abstract description 8
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 6
239000008103 glucose Substances 0.000 claims abstract description 6
230000018044 dehydration Effects 0.000 claims abstract description 4
238000006297 dehydration reaction Methods 0.000 claims abstract description 4
208000005156 Dehydration Diseases 0.000 claims abstract 2
102000019040 Nuclear Antigens Human genes 0.000 claims description 10
108010051791 Nuclear Antigens Proteins 0.000 claims description 10
WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 7
241000283707 Capra Species 0.000 claims description 5
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108060003951 Immunoglobulin Proteins 0.000 claims description 4
230000001413 cellular effect Effects 0.000 claims description 4
102000018358 immunoglobulin Human genes 0.000 claims description 4
238000012151 immunohistochemical method Methods 0.000 claims description 3
VMGAPWLDMVPYIA-HIDZBRGKSA-N n'-amino-n-iminomethanimidamide Chemical compound N\N=C\N=N VMGAPWLDMVPYIA-HIDZBRGKSA-N 0.000 claims description 3
210000005084 renal tissue Anatomy 0.000 claims description 3
BOLDJAUMGUJJKM-LSDHHAIUSA-N renifolin D Natural products CC(=C)[C@@H]1Cc2c(O)c(O)ccc2[C@H]1CC(=O)c3ccc(O)cc3O BOLDJAUMGUJJKM-LSDHHAIUSA-N 0.000 claims description 3
238000010186 staining Methods 0.000 claims description 3
239000011521 glass Substances 0.000 claims description 2
238000011534 incubation Methods 0.000 claims description 2
ZYDGCYWJDWIJCS-UHFFFAOYSA-N 1-methoxyphenazine Chemical compound C1=CC=C2N=C3C(OC)=CC=CC3=NC2=C1 ZYDGCYWJDWIJCS-UHFFFAOYSA-N 0.000 claims 4
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229940072221 immunoglobulins Drugs 0.000 claims 1
238000001514 detection method Methods 0.000 abstract description 5
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract description 3
239000004698 Polyethylene Substances 0.000 abstract description 2
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NIQQIJXGUZVEBB-UHFFFAOYSA-N methanol;propan-2-one Chemical compound OC.CC(C)=O NIQQIJXGUZVEBB-UHFFFAOYSA-N 0.000 abstract 1
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UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
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QLAJNZSPVITUCQ-UHFFFAOYSA-N 1,3,2-dioxathietane 2,2-dioxide Chemical compound O=S1(=O)OCO1 QLAJNZSPVITUCQ-UHFFFAOYSA-N 0.000 description 1
101150034533 ATIC gene Proteins 0.000 description 1
QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 1
229920002799 BoPET Polymers 0.000 description 1
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DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
239000005041 Mylar™ Substances 0.000 description 1
102000004316 Oxidoreductases Human genes 0.000 description 1
108090000854 Oxidoreductases Proteins 0.000 description 1
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
229910052782 aluminium Inorganic materials 0.000 description 1
239000007975 buffered saline Substances 0.000 description 1
238000000502 dialysis Methods 0.000 description 1
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238000001493 electron microscopy Methods 0.000 description 1
238000005562 fading Methods 0.000 description 1
239000008273 gelatin Substances 0.000 description 1
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238000002523 gelfiltration Methods 0.000 description 1
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230000000984 immunochemical effect Effects 0.000 description 1
210000003734 kidney Anatomy 0.000 description 1
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239000003550 marker Substances 0.000 description 1
MYWUZJCMWCOHBA-VIFPVBQESA-N methamphetamine Chemical compound CN[C@@H](C)CC1=CC=CC=C1 MYWUZJCMWCOHBA-VIFPVBQESA-N 0.000 description 1
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230000035515 penetration Effects 0.000 description 1
KHIWWQKSHDUIBK-UHFFFAOYSA-N periodic acid Chemical compound OI(=O)(=O)=O KHIWWQKSHDUIBK-UHFFFAOYSA-N 0.000 description 1
238000007789 sealing Methods 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
239000011734 sodium Substances 0.000 description 1
229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
235000017557 sodium bicarbonate Nutrition 0.000 description 1
239000012064 sodium phosphate buffer Substances 0.000 description 1
CMXPERZAMAQXSF-UHFFFAOYSA-M sodium;1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate;1,8-dihydroxyanthracene-9,10-dione Chemical compound [Na+].O=C1C2=CC=CC(O)=C2C(=O)C2=C1C=CC=C2O.CCCCC(CC)COC(=O)CC(S([O-])(=O)=O)C(=O)OCC(CC)CCCC CMXPERZAMAQXSF-UHFFFAOYSA-M 0.000 description 1
239000007787 solid Substances 0.000 description 1
239000002904 solvent Substances 0.000 description 1
241000894007 species Species 0.000 description 1
230000000087 stabilizing effect Effects 0.000 description 1
238000003756 stirring Methods 0.000 description 1
KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 1
125000003831 tetrazolyl group Chemical group 0.000 description 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
- G01N33/567—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds utilising isolate of tissue or organ as binding agent
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
- G01N33/552—Glass or silica

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
Analytical Chemistry (AREA)
Biotechnology (AREA)
Pathology (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Cell Biology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Inorganic Chemistry (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)

CA000410409A 1981-08-31 1982-08-30 Detection immunohistochimique des anticorps antinucleaires au moyen de la glucose oxydase Expired CA1206092A (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US29811281A	1981-08-31	1981-08-31
US298,112		1981-08-31

Publications (1)

Publication Number	Publication Date
CA1206092A true CA1206092A (fr)	1986-06-17

Family

ID=23149085

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA000410409A Expired CA1206092A (fr)	1981-08-31	1982-08-30	Detection immunohistochimique des anticorps antinucleaires au moyen de la glucose oxydase

Country Status (5)

Country	Link
EP (1)	EP0091911A4 (fr)
CA (1)	CA1206092A (fr)
ES (2)	ES8400773A1 (fr)
IT (1)	IT1153188B (fr)
WO (1)	WO1983000877A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4487830A (en) *	1982-05-14	1984-12-11	American Hoechst Corporation	Enzyme/immunofluorescent assay for autoantibodies
US4588682A (en) *	1982-12-13	1986-05-13	Integrated Genetics, Inc.	Binding nucleic acid to a support
CA1279818C (fr) *	1985-03-29	1991-02-05	Cenfold Holdings S.A.	Test pour la detection des anticorps contre certains micro-organismes
JPS6232363A (ja) *	1985-06-21	1987-02-12	モダン・ダイアグノステイツクス・インコ−ポレ−テツド	抗核抗体の検出方法及び装置
JPS62255869A (ja) *	1986-04-08	1987-11-07	フイツトテイカー　バイオプロダクツ　インコーポレーテツド	免疫螢光顕微鏡検査用の方法と基質
CA1313818C (fr) *	1987-06-03	1993-02-23	Ross Leon Coppel	Antigene nucleaire la
EP0335293A3 (fr) *	1988-03-30	1990-09-12	Hoechst Japan Limited	Procédé pour préparer un élément analytique pour la détermination d'anticorps anti-nucléaire
US7674590B2 (en)	2004-02-20	2010-03-09	Beijing Xinjing Antai Medical And Technology Service Limited Corp.	Methods for diagnosing and for monitoring the treatment of recurrent spontaneous abortion
CN1867342A (zh)	2004-02-20	2006-11-22	北京新景安太医疗技术服务有限公司	反复自然流产的治疗药物及治疗方法
US7763418B2 (en) *	2005-07-05	2010-07-27	Cytoskeleton, Inc.	Detection of Rho proteins

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3146163A (en) *	1962-01-23	1964-08-25	John H Brewer	Apparatus for separating certain components from blood
NL154600B (nl) *	1971-02-10	1977-09-15	Organon Nv	Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
US3997657A (en) *	1973-10-15	1976-12-14	American Cyanamid Company	Dry slide reagent employed in immunofluorescent test for detection of human antinuclear factor
US3876504A (en) *	1974-06-10	1975-04-08	Early Warning Co	Procedure for determination of antigens and antibodies and articles for use therewith
US3979509A (en) *	1974-09-03	1976-09-07	General Electric Company	Opaque layer method for detecting biological particles
DE2836362A1 (de) *	1978-08-19	1980-03-06	Behringwerke Ag	Diagnostisches mittel

1982
- 1982-08-12 EP EP19820902930 patent/EP0091911A4/fr not_active Withdrawn
- 1982-08-12 WO PCT/US1982/001107 patent/WO1983000877A1/fr not_active Ceased
- 1982-08-30 ES ES515350A patent/ES8400773A1/es not_active Expired
- 1982-08-30 CA CA000410409A patent/CA1206092A/fr not_active Expired
- 1982-08-31 IT IT23075/82A patent/IT1153188B/it active
1983
- 1983-07-16 ES ES524183A patent/ES524183A0/es active Granted

Also Published As

Publication number	Publication date
IT1153188B (it)	1987-01-14
IT8223075A0 (it)	1982-08-31
EP0091911A1 (fr)	1983-10-26
ES515350A0 (es)	1983-11-01
ES8500999A1 (es)	1984-11-01
ES8400773A1 (es)	1983-11-01
ES524183A0 (es)	1984-11-01
WO1983000877A1 (fr)	1983-03-17
EP0091911A4 (fr)	1984-04-06

Legal Events

Date	Code	Title	Description
2003-06-17	MKEX	Expiry

Publication	Publication Date	Title
US4487830A (en)	1984-12-11	Enzyme/immunofluorescent assay for autoantibodies
US5225325A (en)	1993-07-06	Immunohistochemical staining method and reagents therefor
US4302534A (en)	1981-11-24	Chemiluminescent enzyme immunoassay
Viitala et al.	1997	Serum IgA, IgG, and IgM antibodies directed against acetaldehyde‐derived epitopes: relationship to liver disease severity and alcohol consumption
US6916626B1 (en)	2005-07-12	Detection of Candida
US11913965B2 (en)	2024-02-27	Sandwich assay for small molecules
CA1206092A (fr)	1986-06-17	Detection immunohistochimique des anticorps antinucleaires au moyen de la glucose oxydase
FI75677C (fi)	1988-07-11	Testanordning foer bestaemning av en ligand i ett vaetskeprov medelst homogen immunoanalys, foerfarande foer framstaellning av denna och med anvaendning av anordningen utfoert analytiskt foerfarande.
US4816392A (en)	1989-03-28	Rapid stick test for detection of ciguatoxin and other polyether toxins from tissues
US5780243A (en)	1998-07-14	Methods for the quantitative analysis of organic compounds
US5780239A (en)	1998-07-14	Method for the determination of cast in urine
US5998156A (en)	1999-12-07	Color developing method, enzyme immunoassay using the color developing method, and immunochromatography incorporating the enzyme immunoassay
CA1104927A (fr)	1981-07-14	Traduction non-disponible
CA2104967A1 (fr)	1993-07-07	Dosage de proteines de liaison par capture
FI68653B (fi)	1985-06-28	Metod foer bestaemning av tyroxin-bindningsindex i serum och testfoerpackning foer utfoerande av bestaemningen
Jennette	1988	Immunohistology in diagnostic pathology
Yoshida et al.	1999	Changes of sinusoidal basement membrane collagens in early hepatic fibrosis induced with CCl4 in cynomolgus monkeys
CN111273041B (zh)	2023-09-19	一种检测鬼笔环肽的酶联免疫试剂盒及其制备和应用
CA2239882C (fr)	2003-07-29	Procede pour determiner ou detecter des dommages a l'organe donneur a la suite d'une xenotransplantation, a l'aide des analytes derives de l'organe donneur
Baron et al.	1986	Immunohistochemistry
RU2157540C2 (ru)	2000-10-10	Способ определения или обнаружения повреждения органа-донора после ксенотрансплантации на основе анализа веществ, полученных из органа-донора
US5998157A (en)	1999-12-07	Acylated protein aggregates and their use as signal enhancers in an immunoassay for the detection of antibodies
JPS6042654A (ja)	1985-03-06	グルコ−スオキシダ−ゼ使用による抗核抗体の免疫組織化学的検査方法
Redick	1986	Jeffrey Baron, Jeffrey M. Voigt, Thomas T. Kawabata
JPH06181762A (ja)	1994-07-05	標識抗体組成物