CA1215042A - Methode de preparation d'esters penem - Google Patents

Methode de preparation d'esters penem

Info

Publication number
CA1215042A
CA1215042A CA000444654A CA444654A CA1215042A CA 1215042 A CA1215042 A CA 1215042A CA 000444654 A CA000444654 A CA 000444654A CA 444654 A CA444654 A CA 444654A CA 1215042 A CA1215042 A CA 1215042A
Authority
CA
Canada
Prior art keywords
penem
group
formula
compound
carboxylate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000444654A
Other languages
English (en)
Inventor
Maurizio Foglio
Giovanni Franceschi
Aurora Sanfilippo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Application granted granted Critical
Publication of CA1215042A publication Critical patent/CA1215042A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/86—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
CA000444654A 1983-01-06 1984-01-04 Methode de preparation d'esters penem Expired CA1215042A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8300295 1983-01-06
GB838300295A GB8300295D0 (en) 1983-01-06 1983-01-06 Penem esters

Publications (1)

Publication Number Publication Date
CA1215042A true CA1215042A (fr) 1986-12-09

Family

ID=10535987

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000444654A Expired CA1215042A (fr) 1983-01-06 1984-01-04 Methode de preparation d'esters penem

Country Status (31)

Country Link
US (1) US5051416A (fr)
JP (1) JPS59134795A (fr)
KR (1) KR900004418B1 (fr)
AT (1) AT382622B (fr)
AU (1) AU557178B2 (fr)
BE (1) BE898603A (fr)
CA (1) CA1215042A (fr)
CH (1) CH659073A5 (fr)
CS (2) CS235996B2 (fr)
DE (1) DE3400090A1 (fr)
DK (1) DK166387C (fr)
ES (1) ES528546A0 (fr)
FI (1) FI81103C (fr)
FR (1) FR2539130B1 (fr)
GB (2) GB8300295D0 (fr)
GR (1) GR81730B (fr)
HK (1) HK74987A (fr)
HU (1) HU191243B (fr)
IE (1) IE56903B1 (fr)
IL (1) IL70606A (fr)
IT (1) IT1209490B (fr)
NL (1) NL8400015A (fr)
NO (1) NO160446C (fr)
NZ (1) NZ206743A (fr)
PH (1) PH18881A (fr)
PT (1) PT77922B (fr)
SE (1) SE458117B (fr)
SG (1) SG34387G (fr)
SU (1) SU1209031A3 (fr)
UA (1) UA6039A1 (fr)
ZA (1) ZA8457B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364768A (en) * 1987-07-07 1994-11-15 Farmitalia Carlo Erba S.R.L. Process for the preparation of penems
GB2206578B (en) * 1987-07-07 1991-07-03 Erba Carlo Spa Process for the preparation of penems
EP0937725A3 (fr) 1992-04-28 2004-12-01 Tanabe Seiyaku Co., Ltd. Méthode pour débloquer un groupe hydroxyle protégé

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7401782A (fr) * 1973-02-14 1974-08-16
ZA80993B (en) * 1979-02-24 1981-02-25 Erba Farmitalia -lactam-containing antibacterial agents and -lactamase inhibitors and preparation thereof
AT368506B (de) * 1979-02-24 1982-10-25 Erba Farmitalia Verfahren zur herstellung von neuen penemcarbonsaeuren und deren salzen
GB2043699B (en) * 1979-03-03 1983-05-11 Park Chem Co Cyanide-free carburizing process and composition
US4482565A (en) * 1980-02-22 1984-11-13 Farmitalia Carlo Erba S.P.A. β-Lactam-containing antibacterial agents and β-lactamase inhibitors
NL8204720A (nl) * 1981-12-11 1983-07-01 Erba Farmitalia Werkwijze voor het bereiden van optisch actieve penemverbindingen.

Also Published As

Publication number Publication date
GB2133010B (en) 1986-02-19
SG34387G (en) 1987-07-24
CS415091A3 (en) 1992-06-17
FI81103B (fi) 1990-05-31
FI81103C (fi) 1990-09-10
FI840003A7 (fi) 1984-07-07
GB8400043D0 (en) 1984-02-08
US5051416A (en) 1991-09-24
DE3400090A1 (de) 1984-07-12
IT1209490B (it) 1989-08-30
DK166387B (da) 1993-05-10
DK5284A (da) 1984-07-07
CS235996B2 (en) 1985-05-15
KR900004418B1 (ko) 1990-06-25
SE8400040L (sv) 1984-07-07
HK74987A (en) 1987-10-23
PT77922A (en) 1984-02-01
IE56903B1 (en) 1992-01-29
IL70606A (en) 1988-03-31
GB2133010A (en) 1984-07-18
CH659073A5 (de) 1986-12-31
NO160446B (no) 1989-01-09
IT8419007A0 (it) 1984-01-03
IL70606A0 (en) 1984-04-30
SE458117B (sv) 1989-02-27
ZA8457B (en) 1984-08-29
AT382622B (de) 1987-03-25
GR81730B (fr) 1984-12-12
AU557178B2 (en) 1986-12-11
ES8505372A1 (es) 1985-05-16
NL8400015A (nl) 1984-08-01
ATA1584A (de) 1986-08-15
AU2304784A (en) 1984-07-12
KR840007414A (ko) 1984-12-07
SE8400040D0 (sv) 1984-01-04
JPS59134795A (ja) 1984-08-02
JPH0414679B2 (fr) 1992-03-13
NO160446C (no) 1989-04-19
PT77922B (en) 1986-06-02
FR2539130A1 (fr) 1984-07-13
DK166387C (da) 1993-09-27
SU1209031A3 (ru) 1986-01-30
NZ206743A (en) 1987-02-20
UA6039A1 (uk) 1994-12-29
IE840006L (en) 1984-07-06
BE898603A (fr) 1984-07-04
ES528546A0 (es) 1985-05-16
DK5284D0 (da) 1984-01-05
GB8300295D0 (en) 1983-02-09
FR2539130B1 (fr) 1985-10-18
NO840035L (no) 1984-07-09
PH18881A (en) 1985-10-22
FI840003A0 (fi) 1984-01-02
HU191243B (en) 1987-01-28

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Legal Events

Date Code Title Description
MKEX Expiry