CA1231046A - Composition renfermant de l'imidazolidinyluree et des parabens - Google Patents

Composition renfermant de l'imidazolidinyluree et des parabens

Info

Publication number: CA1231046A
Authority: CA; Canada
Prior art keywords: composition; weight; imidazolidinyl urea; parabens; propylparaben
Prior art date: 1982-08-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA000433967A

Other languages

English (en)

Inventor

William E. Rosen

Philip A. Berke

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

SUTTON LABORATORIES Inc

Original Assignee

SUTTON LABORATORIES Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-08-06

Filing date

1983-08-05

Publication date

1988-01-05

1983-08-05 Application filed by SUTTON LABORATORIES Inc filed Critical SUTTON LABORATORIES Inc

1988-01-05 Application granted granted Critical

1988-01-05 Publication of CA1231046A publication Critical patent/CA1231046A/fr

Status Expired legal-status Critical Current

Links

239000000203 mixture Substances 0.000 title claims abstract description 27
ZCTXEAQXZGPWFG-UHFFFAOYSA-N imidurea Chemical compound O=C1NC(=O)N(CO)C1NC(=O)NCNC(=O)NC1C(=O)NC(=O)N1CO ZCTXEAQXZGPWFG-UHFFFAOYSA-N 0.000 title claims abstract description 19
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 27
LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims abstract description 20
QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 claims abstract description 20
235000010270 methyl p-hydroxybenzoate Nutrition 0.000 claims abstract description 11
235000010232 propyl p-hydroxybenzoate Nutrition 0.000 claims abstract description 11
239000004292 methyl p-hydroxybenzoate Substances 0.000 claims abstract description 10
229960002216 methylparaben Drugs 0.000 claims abstract description 10
239000004405 propyl p-hydroxybenzoate Substances 0.000 claims abstract description 10
229960003415 propylparaben Drugs 0.000 claims abstract description 10
241000894006 Bacteria Species 0.000 abstract description 5
240000004808 Saccharomyces cerevisiae Species 0.000 abstract description 5
230000000694 effects Effects 0.000 abstract description 4
238000004321 preservation Methods 0.000 abstract description 4
244000005700 microbiome Species 0.000 abstract description 2
230000001747 exhibiting effect Effects 0.000 abstract 1
239000000047 product Substances 0.000 description 18
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 14
239000002537 cosmetic Substances 0.000 description 7
239000012085 test solution Substances 0.000 description 7
FJKROLUGYXJWQN-UHFFFAOYSA-N 4-hydroxybenzoic acid Chemical compound OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 6
239000000839 emulsion Substances 0.000 description 6
238000010438 heat treatment Methods 0.000 description 6
238000000034 method Methods 0.000 description 5
239000003755 preservative agent Substances 0.000 description 5
230000002335 preservative effect Effects 0.000 description 5
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 4
150000001875 compounds Chemical class 0.000 description 4
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 4
241000228245 Aspergillus niger Species 0.000 description 3
241000589517 Pseudomonas aeruginosa Species 0.000 description 3
239000008346 aqueous phase Substances 0.000 description 3
239000004202 carbamide Substances 0.000 description 3
230000006378 damage Effects 0.000 description 3
239000007788 liquid Substances 0.000 description 3
230000000813 microbial effect Effects 0.000 description 3
239000003921 oil Substances 0.000 description 3
239000000243 solution Substances 0.000 description 3
LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 2
230000000845 anti-microbial effect Effects 0.000 description 2
238000011109 contamination Methods 0.000 description 2
239000006071 cream Substances 0.000 description 2
125000002632 imidazolidinyl group Chemical group 0.000 description 2
239000006210 lotion Substances 0.000 description 2
239000012071 phase Substances 0.000 description 2
238000002360 preparation method Methods 0.000 description 2
239000000126 substance Substances 0.000 description 2
238000009631 Broth culture Methods 0.000 description 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
239000002253 acid Substances 0.000 description 1
230000000844 anti-bacterial effect Effects 0.000 description 1
238000009835 boiling Methods 0.000 description 1
235000013877 carbamide Nutrition 0.000 description 1
238000001816 cooling Methods 0.000 description 1
239000013078 crystal Substances 0.000 description 1
238000010790 dilution Methods 0.000 description 1
239000012895 dilution Substances 0.000 description 1
238000004090 dissolution Methods 0.000 description 1
150000002148 esters Chemical class 0.000 description 1
239000000706 filtrate Substances 0.000 description 1
238000009472 formulation Methods 0.000 description 1
WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
-1 i.e. Substances 0.000 description 1
238000011534 incubation Methods 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
238000012986 modification Methods 0.000 description 1
230000004048 modification Effects 0.000 description 1
239000003960 organic solvent Substances 0.000 description 1
239000008194 pharmaceutical composition Substances 0.000 description 1
238000003672 processing method Methods 0.000 description 1
239000002453 shampoo Substances 0.000 description 1
159000000000 sodium salts Chemical class 0.000 description 1
239000007787 solid Substances 0.000 description 1
239000002904 solvent Substances 0.000 description 1
238000003756 stirring Methods 0.000 description 1
238000006467 substitution reaction Methods 0.000 description 1
239000000725 suspension Substances 0.000 description 1
229940045136 urea Drugs 0.000 description 1
238000005303 weighing Methods 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/36—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< directly attached to at least one heterocyclic ring; Thio analogues thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/524—Preservatives

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Birds (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Environmental Sciences (AREA)
Emergency Medicine (AREA)
Wood Science & Technology (AREA)
Dentistry (AREA)
Plant Pathology (AREA)
Pest Control & Pesticides (AREA)
Agronomy & Crop Science (AREA)
Dermatology (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Medicinal Preparation (AREA)
Cosmetics (AREA)

CA000433967A 1982-08-06 1983-08-05 Composition renfermant de l'imidazolidinyluree et des parabens Expired CA1231046A (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US40601782A	1982-08-06	1982-08-06
US406,017		1982-08-06

Publications (1)

Publication Number	Publication Date
CA1231046A true CA1231046A (fr)	1988-01-05

Family

ID=23606197

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA000433967A Expired CA1231046A (fr)	1982-08-06	1983-08-05	Composition renfermant de l'imidazolidinyluree et des parabens

Country Status (4)

Country	Link
CA (1)	CA1231046A (fr)
DE (1)	DE3328372A1 (fr)
FR (1)	FR2531336B1 (fr)
GB (1)	GB2126089B (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8969390B2 (en)	2009-05-23	2015-03-03	Clariant Finance (Bvi) Limited	Composition containing sorbitan monocaprylate and antimicrobial substances
US9295626B2 (en)	2011-08-04	2016-03-29	Clariant International Ltd.	Compositions comprising isosorbide monoester and N-hydroxypyridones
US9358199B2 (en)	2011-08-04	2016-06-07	Clariant International Ltd.	Use of isosorbide diesters as thickeners
US9445595B2 (en)	2011-08-04	2016-09-20	Clariant International Ltd.	Composition containing isosorbide monoester and isosorbide diester
US9555117B2 (en)	2011-08-04	2017-01-31	Clariant International Ltd.	Use of isosorbide monoesters as thickeners
US9596849B2 (en)	2009-05-23	2017-03-21	Clariant International Ltd.	Composition containing sorbitan monocaprylate and alcohol
US9730450B2 (en)	2011-08-04	2017-08-15	Clariant International Ltd.	Use of isosorbide monoesters as antimicrobial active substances
US10406135B2 (en)	2011-08-04	2019-09-10	Clariant International Ltd.	Compositions containing isosorbide monoester and alcohols that contain at least one aromatic group

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3508928A1 (de) *	1985-03-13	1986-09-18	Giulini Chemie Gmbh, 6700 Ludwigshafen	Kombination zur antimikrobiellen und antioxidativen stabilisierung von externa und koerperpflegemitteln
FR2579463B1 (fr) *	1985-03-26	1988-01-29	Bensimon Claudine	Composition therapeutique a base d'imidazolidinyluree pour le traitement des manifestations cutanees de l'acne
AU618808B2 (en) *	1988-05-16	1992-01-09	Protech Incorporated	Stabilizer composition and stabilized aqueous systems

1983
- 1983-08-05 GB GB08321167A patent/GB2126089B/en not_active Expired
- 1983-08-05 CA CA000433967A patent/CA1231046A/fr not_active Expired
- 1983-08-05 FR FR8312984A patent/FR2531336B1/fr not_active Expired
- 1983-08-05 DE DE19833328372 patent/DE3328372A1/de not_active Withdrawn

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8969390B2 (en)	2009-05-23	2015-03-03	Clariant Finance (Bvi) Limited	Composition containing sorbitan monocaprylate and antimicrobial substances
US9596849B2 (en)	2009-05-23	2017-03-21	Clariant International Ltd.	Composition containing sorbitan monocaprylate and alcohol
US9295626B2 (en)	2011-08-04	2016-03-29	Clariant International Ltd.	Compositions comprising isosorbide monoester and N-hydroxypyridones
US9358199B2 (en)	2011-08-04	2016-06-07	Clariant International Ltd.	Use of isosorbide diesters as thickeners
US9445595B2 (en)	2011-08-04	2016-09-20	Clariant International Ltd.	Composition containing isosorbide monoester and isosorbide diester
US9555117B2 (en)	2011-08-04	2017-01-31	Clariant International Ltd.	Use of isosorbide monoesters as thickeners
US9730450B2 (en)	2011-08-04	2017-08-15	Clariant International Ltd.	Use of isosorbide monoesters as antimicrobial active substances
US9968536B2 (en)	2011-08-04	2018-05-15	Clariant International Ltd.	Composition comprising isosorbide monoesters and isosorbide diesters
US10406135B2 (en)	2011-08-04	2019-09-10	Clariant International Ltd.	Compositions containing isosorbide monoester and alcohols that contain at least one aromatic group

Also Published As

Publication number	Publication date
FR2531336B1 (fr)	1987-10-02
DE3328372A1 (de)	1984-03-01
GB2126089A (en)	1984-03-21
GB2126089B (en)	1985-11-06
GB8321167D0 (en)	1983-09-07
FR2531336A1 (fr)	1984-02-10

Legal Events

Date	Code	Title	Description
2005-01-05	MKEX	Expiry

Publication	Publication Date	Title
US4581351A (en)	1986-04-08	Composition of matter containing imidazolidinyl urea and pyrithione and its derivatives
US5707993A (en)	1998-01-13	Glycine anhydride dimethylol as a biocide and preservative
US6120758A (en)	2000-09-19	Preservative system for topically applied products
JP4285913B2 (ja)	2009-06-24	化粧品を保護するための液体濃縮物
CA1231046A (fr)	1988-01-05	Composition renfermant de l'imidazolidinyluree et des parabens
KR100541271B1 (ko)	2006-04-21	국소적 사용을 위한 항균조성물
PH26546A (en)	1992-08-19	Topical preparation containing ofloxacin
CA2093045C (fr)	1997-03-18	Methode de preparation de methylolhydantoines exemptes de formaldehyde et compositions a base de ces produits
JPS61191601A (ja)	1986-08-26	水含有組成物中の微生物の制御
MXPA93003006A (en)	1997-08-01	A method for preparing methylolydanthines contained free formaldehyde content and compositions of myself
CA1155129A (fr)	1983-10-11	N-(hydroxymethyl)-n-(1,3-dihydroxymethyl-2,5 dioxo-4-imidazolidinyl)-n-(hydroxymethyl) uree et agent de conservation la contenant
KR20220058468A (ko)	2022-05-09	알칸디올, 및 카프릴릴글리세릴에터 또는 에틸헥실글리세린을 포함하는 피부 외용제용 보존제 및 이를 포함하는 화장료 조성물
EP0892785B1 (fr)	2001-07-25	Solution antimicrobienne de hydantoine substituee par formaldehyde et procede de preparation
EP4427729A1 (fr)	2024-09-11	Conservateur pour application cutanée externe comprenant du magnolol, de l'honokiol, ou une combinaison de ceux-ci, et composition cosmétique le comprenant
EP1892236B9 (fr)	2012-01-18	Iodures d'éster d'acides gras de diméthylaminoéthanol dotés d'une activité bactériostatique, mycostatique, levurostatique et/ou microbicide pour une utilisation dans des formulations de nettoyage ou de purification
WO2019121380A1 (fr)	2019-06-27	Préparation désinfectante colorée à teneur en dichlorhydrate d'octénidine
CN116421481A (zh)	2023-07-14	一种复配防腐剂及其制备方法
US4076744A (en)	1978-02-28	Amphoteric surfactants
US6063388A (en)	2000-05-16	Preserving system and its use in a cosmetic or pharmaceutical composition
EP0076430B1 (fr)	1986-06-18	Composition à activité microbicide
US3519414A (en)	1970-07-07	Algaetoxic,synergistic compositions of aza - 1 - cycloheptenes and quaternary ammonium compounds and method of use
KR102227751B1 (ko)	2021-03-15	오미자, 백리향 및 꽃향유의 추출 혼합물을 유효성분으로 함유하는 천연 방부대체제 및 이의 용도
CN118236280A (zh)	2024-06-25	一种1,2-苯并异噻唑啉-3-酮水悬浮制剂及其制备方法
WO1984002058A1 (fr)	1984-06-07	Composition de substance contenant de l'imidazolidinyle-uree, de la pyrithione ainsi que des derives de cette derniere
CN120284788A (zh)	2025-07-11	一种多功能天然复配物及其应用