CA1231281A - Dispositif inhibiteur pour systeme de perfusion prgrammable - Google Patents
Dispositif inhibiteur pour systeme de perfusion prgrammableInfo
- Publication number
- CA1231281A CA1231281A CA000486976A CA486976A CA1231281A CA 1231281 A CA1231281 A CA 1231281A CA 000486976 A CA000486976 A CA 000486976A CA 486976 A CA486976 A CA 486976A CA 1231281 A CA1231281 A CA 1231281A
- Authority
- CA
- Canada
- Prior art keywords
- infusion
- rate
- medication
- pulses
- unit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000001802 infusion Methods 0.000 title claims abstract description 98
- 230000002401 inhibitory effect Effects 0.000 title claims abstract description 24
- 239000003814 drug Substances 0.000 claims abstract description 148
- 229940079593 drug Drugs 0.000 claims abstract description 146
- 238000002513 implantation Methods 0.000 claims description 2
- 230000036962 time dependent Effects 0.000 claims description 2
- 239000000919 ceramic Substances 0.000 description 18
- 230000000541 pulsatile effect Effects 0.000 description 14
- 238000004891 communication Methods 0.000 description 12
- 239000012530 fluid Substances 0.000 description 12
- 230000000638 stimulation Effects 0.000 description 11
- 210000001124 body fluid Anatomy 0.000 description 10
- 239000010839 body fluid Substances 0.000 description 10
- 239000007788 liquid Substances 0.000 description 9
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 8
- 238000000034 method Methods 0.000 description 8
- 238000007920 subcutaneous administration Methods 0.000 description 8
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 7
- 230000007257 malfunction Effects 0.000 description 7
- 230000006870 function Effects 0.000 description 5
- 239000011780 sodium chloride Substances 0.000 description 5
- 102000004877 Insulin Human genes 0.000 description 4
- 108090001061 Insulin Proteins 0.000 description 4
- 229940125396 insulin Drugs 0.000 description 4
- 235000012054 meals Nutrition 0.000 description 4
- AJDIZQLSFPQPEY-UHFFFAOYSA-N 1,1,2-Trichlorotrifluoroethane Chemical compound FC(F)(Cl)C(F)(Cl)Cl AJDIZQLSFPQPEY-UHFFFAOYSA-N 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 239000000356 contaminant Substances 0.000 description 3
- 230000009977 dual effect Effects 0.000 description 3
- 229920001971 elastomer Polymers 0.000 description 3
- 230000003993 interaction Effects 0.000 description 3
- 230000000670 limiting effect Effects 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 238000005086 pumping Methods 0.000 description 3
- 230000004044 response Effects 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 230000000007 visual effect Effects 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 241001481828 Glyptocephalus cynoglossus Species 0.000 description 2
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 2
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- OJIJEKBXJYRIBZ-UHFFFAOYSA-N cadmium nickel Chemical compound [Ni].[Cd] OJIJEKBXJYRIBZ-UHFFFAOYSA-N 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000003467 diminishing effect Effects 0.000 description 2
- NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 description 2
- 230000037406 food intake Effects 0.000 description 2
- 235000012631 food intake Nutrition 0.000 description 2
- 229910021397 glassy carbon Inorganic materials 0.000 description 2
- 229960002897 heparin Drugs 0.000 description 2
- 229920000669 heparin Polymers 0.000 description 2
- 239000007943 implant Substances 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 229910052744 lithium Inorganic materials 0.000 description 2
- 238000009877 rendering Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 208000032368 Device malfunction Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000220010 Rhode Species 0.000 description 1
- 241000120694 Thestor Species 0.000 description 1
- 230000010100 anticoagulation Effects 0.000 description 1
- 239000002246 antineoplastic agent Substances 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 235000021152 breakfast Nutrition 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 229940127089 cytotoxic agent Drugs 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000003205 diastolic effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229960001031 glucose Drugs 0.000 description 1
- 231100001261 hazardous Toxicity 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000008676 import Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000003507 refrigerant Substances 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 230000011664 signaling Effects 0.000 description 1
- 238000004088 simulation Methods 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 235000011888 snacks Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
Landscapes
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA000486976A CA1231281A (fr) | 1982-12-17 | 1985-07-17 | Dispositif inhibiteur pour systeme de perfusion prgrammable |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA000417979A CA1193934A (fr) | 1982-12-17 | 1982-12-17 | Systeme implantable et programmable pour la perfusion de medicaments |
| CA000486976A CA1231281A (fr) | 1982-12-17 | 1985-07-17 | Dispositif inhibiteur pour systeme de perfusion prgrammable |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000417979A Division CA1193934A (fr) | 1982-12-17 | 1982-12-17 | Systeme implantable et programmable pour la perfusion de medicaments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1231281A true CA1231281A (fr) | 1988-01-12 |
Family
ID=4124170
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000417979A Expired CA1193934A (fr) | 1982-12-17 | 1982-12-17 | Systeme implantable et programmable pour la perfusion de medicaments |
| CA000486976A Expired CA1231281A (fr) | 1982-12-17 | 1985-07-17 | Dispositif inhibiteur pour systeme de perfusion prgrammable |
| CA000486993A Expired CA1231282A (fr) | 1982-12-17 | 1985-07-17 | Dispositif de pompage pour systeme de perfusion programmable |
| CA000486992A Expired CA1206832A (fr) | 1982-12-17 | 1985-07-17 | Dispositif d'alarme pour systeme de perfusion programmable |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000417979A Expired CA1193934A (fr) | 1982-12-17 | 1982-12-17 | Systeme implantable et programmable pour la perfusion de medicaments |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000486993A Expired CA1231282A (fr) | 1982-12-17 | 1985-07-17 | Dispositif de pompage pour systeme de perfusion programmable |
| CA000486992A Expired CA1206832A (fr) | 1982-12-17 | 1985-07-17 | Dispositif d'alarme pour systeme de perfusion programmable |
Country Status (1)
| Country | Link |
|---|---|
| CA (4) | CA1193934A (fr) |
-
1982
- 1982-12-17 CA CA000417979A patent/CA1193934A/fr not_active Expired
-
1985
- 1985-07-17 CA CA000486976A patent/CA1231281A/fr not_active Expired
- 1985-07-17 CA CA000486993A patent/CA1231282A/fr not_active Expired
- 1985-07-17 CA CA000486992A patent/CA1206832A/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CA1193934A (fr) | 1985-09-24 |
| CA1206832A (fr) | 1986-07-02 |
| CA1231282A (fr) | 1988-01-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |