CA1260894A - Apparatus for sealing capsules - Google Patents
Apparatus for sealing capsulesInfo
- Publication number
- CA1260894A CA1260894A CA000456169A CA456169A CA1260894A CA 1260894 A CA1260894 A CA 1260894A CA 000456169 A CA000456169 A CA 000456169A CA 456169 A CA456169 A CA 456169A CA 1260894 A CA1260894 A CA 1260894A
- Authority
- CA
- Canada
- Prior art keywords
- capsule
- capsules
- conveyor
- fluid
- washing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002775 capsule Substances 0.000 title claims abstract description 202
- 238000007789 sealing Methods 0.000 title claims abstract description 16
- 239000012530 fluid Substances 0.000 claims abstract description 91
- 238000005406 washing Methods 0.000 claims abstract description 49
- 238000001035 drying Methods 0.000 claims abstract description 27
- 239000007921 spray Substances 0.000 claims description 20
- 238000010438 heat treatment Methods 0.000 claims description 11
- 230000001737 promoting effect Effects 0.000 claims description 3
- 238000007599 discharging Methods 0.000 claims 1
- 238000012545 processing Methods 0.000 abstract description 5
- 238000000034 method Methods 0.000 description 20
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 12
- 239000002904 solvent Substances 0.000 description 12
- 238000010276 construction Methods 0.000 description 11
- VZGDMQKNWNREIO-UHFFFAOYSA-N tetrachloromethane Chemical compound ClC(Cl)(Cl)Cl VZGDMQKNWNREIO-UHFFFAOYSA-N 0.000 description 8
- 108010010803 Gelatin Proteins 0.000 description 7
- 238000004891 communication Methods 0.000 description 7
- 229920000159 gelatin Polymers 0.000 description 7
- 239000008273 gelatin Substances 0.000 description 7
- 235000019322 gelatine Nutrition 0.000 description 7
- 235000011852 gelatine desserts Nutrition 0.000 description 7
- 239000007788 liquid Substances 0.000 description 7
- 238000011282 treatment Methods 0.000 description 7
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 6
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 6
- 229950005499 carbon tetrachloride Drugs 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 230000003134 recirculating effect Effects 0.000 description 4
- 239000003814 drug Substances 0.000 description 3
- 238000009434 installation Methods 0.000 description 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- 239000003208 petroleum Substances 0.000 description 3
- 230000001154 acute effect Effects 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 238000000429 assembly Methods 0.000 description 2
- 230000000712 assembly Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 238000012423 maintenance Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000002574 poison Substances 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 241001527902 Aratus Species 0.000 description 1
- XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- LZCDAPDGXCYOEH-UHFFFAOYSA-N adapalene Chemical compound C1=C(C(O)=O)C=CC2=CC(C3=CC=C(C(=C3)C34CC5CC(CC(C5)C3)C4)OC)=CC=C21 LZCDAPDGXCYOEH-UHFFFAOYSA-N 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 238000004380 ashing Methods 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 239000007963 capsule composition Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 229940002658 differin Drugs 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 239000007903 gelatin capsule Substances 0.000 description 1
- -1 hex2ne Substances 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 231100000518 lethal Toxicity 0.000 description 1
- 230000001665 lethal effect Effects 0.000 description 1
- 230000033001 locomotion Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- VOVZXURTCKPRDQ-CQSZACIVSA-N n-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3r)-3-hydroxypyrrolidin-1-yl]-5-(1h-pyrazol-5-yl)pyridine-3-carboxamide Chemical compound C1[C@H](O)CCN1C1=NC=C(C(=O)NC=2C=CC(OC(F)(F)Cl)=CC=2)C=C1C1=CC=NN1 VOVZXURTCKPRDQ-CQSZACIVSA-N 0.000 description 1
- 239000005445 natural material Substances 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000013557 residual solvent Substances 0.000 description 1
- 239000012260 resinous material Substances 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000005063 solubilization Methods 0.000 description 1
- 230000007928 solubilization Effects 0.000 description 1
- 238000007614 solvation Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000009827 uniform distribution Methods 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
- A61J3/072—Sealing capsules, e.g. rendering them tamper-proof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Formation And Processing Of Food Products (AREA)
- Closing Of Containers (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50395083A | 1983-06-13 | 1983-06-13 | |
| US503,950 | 1983-06-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1260894A true CA1260894A (en) | 1989-09-26 |
Family
ID=24004203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000456169A Expired CA1260894A (en) | 1983-06-13 | 1984-06-08 | Apparatus for sealing capsules |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0129130B1 (de) |
| JP (1) | JPS6024845A (de) |
| AT (1) | ATE32560T1 (de) |
| CA (1) | CA1260894A (de) |
| DE (1) | DE3469408D1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH674800A5 (de) * | 1986-03-12 | 1990-07-31 | Warner Lambert Co | |
| JP2569830B2 (ja) * | 1989-10-05 | 1997-01-08 | 東レ株式会社 | 多角形中空断面糸およびその製造方法 |
| US5544631A (en) * | 1994-10-05 | 1996-08-13 | Outboard Marine Corporation | Cylinder head construction for outboard motor with four-stroke engine |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1861047A (en) * | 1929-05-13 | 1932-05-31 | Parke Davis & Co | Sealed capsule |
| US3394983A (en) * | 1963-06-14 | 1968-07-30 | American Cyanamid Co | Dip-dyeing capsules |
| EP0116744A1 (de) * | 1982-12-20 | 1984-08-29 | Warner-Lambert Company | Vorrichtung und Verfahren zum Versiegeln von Kapseln |
| US4539060A (en) * | 1983-02-18 | 1985-09-03 | Warner-Lambert Company | Apparatus and method of sealing capsules |
| US4820364A (en) * | 1983-05-23 | 1989-04-11 | Capsulbond Incorporated | Method for sealing capsules |
-
1984
- 1984-06-04 DE DE8484106344T patent/DE3469408D1/de not_active Expired
- 1984-06-04 EP EP84106344A patent/EP0129130B1/de not_active Expired
- 1984-06-04 AT AT84106344T patent/ATE32560T1/de not_active IP Right Cessation
- 1984-06-08 CA CA000456169A patent/CA1260894A/en not_active Expired
- 1984-06-13 JP JP59122900A patent/JPS6024845A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ATE32560T1 (de) | 1988-03-15 |
| DE3469408D1 (en) | 1988-03-31 |
| EP0129130A3 (en) | 1985-05-15 |
| EP0129130A2 (de) | 1984-12-27 |
| EP0129130B1 (de) | 1988-02-24 |
| JPS6024845A (ja) | 1985-02-07 |
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| JPH02946B2 (de) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |