CA1299576C - Process for the production of tizanidine - Google Patents

Process for the production of tizanidine

Info

Publication number
CA1299576C
CA1299576C CA000532965A CA532965A CA1299576C CA 1299576 C CA1299576 C CA 1299576C CA 000532965 A CA000532965 A CA 000532965A CA 532965 A CA532965 A CA 532965A CA 1299576 C CA1299576 C CA 1299576C
Authority
CA
Canada
Prior art keywords
chloro
mixture
benzothiadiazole
minutes
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000532965A
Other languages
English (en)
French (fr)
Inventor
Ljubomir Conrad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of CA1299576C publication Critical patent/CA1299576C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CA000532965A 1986-03-27 1987-03-25 Process for the production of tizanidine Expired - Lifetime CA1299576C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19863610407 DE3610407A1 (de) 1986-03-27 1986-03-27 Verfahren zur herstellung von tizanidin
DEP3610407.8 1986-03-27

Publications (1)

Publication Number Publication Date
CA1299576C true CA1299576C (en) 1992-04-28

Family

ID=6297425

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000532965A Expired - Lifetime CA1299576C (en) 1986-03-27 1987-03-25 Process for the production of tizanidine

Country Status (7)

Country Link
KR (1) KR960001725B1 (de)
AT (1) AT396237B (de)
CA (1) CA1299576C (de)
DE (1) DE3610407A1 (de)
HU (1) HU197005B (de)
IT (1) IT1216800B (de)
MX (1) MX172623B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110263863A1 (en) * 2008-12-18 2011-10-27 Pavel Hradil Method for the preparation of tizanidine hydrochloride

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2234506C1 (ru) * 2003-06-05 2004-08-20 Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" Способ получения 5-хлор-4-/(2-имидазолин-2-ил)амино/-2,1,3-бензотиадиазола хлоргидрата

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH599207A5 (de) * 1973-03-15 1978-05-12 Wander Ag Dr A
AU505664B2 (en) * 1977-04-12 1979-11-29 Wander A.G. 2, 1, 3-benzothiadiazoles

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110263863A1 (en) * 2008-12-18 2011-10-27 Pavel Hradil Method for the preparation of tizanidine hydrochloride
US8487113B2 (en) * 2008-12-18 2013-07-16 Farmak, A.S. Method for the preparation of tizanidine hydrochloride

Also Published As

Publication number Publication date
HUT43596A (en) 1987-11-30
IT8747764A0 (it) 1987-03-24
KR960001725B1 (ko) 1996-02-03
AT396237B (de) 1993-07-26
DE3610407A1 (de) 1987-10-01
IT1216800B (it) 1990-03-14
ATA73487A (de) 1992-11-15
KR880012600A (ko) 1988-11-28
HU197005B (en) 1989-02-28
MX172623B (es) 1994-01-04

Similar Documents

Publication Publication Date Title
CA2634811C (en) Novel modifications to 2-amino-4-(4-fluorobenzylamino) -1- ethoxycarbonyl-aminobenzene and processes for preparing said compound
US4826973A (en) Delta form of aztreonam and preparation thereof
CA1299576C (en) Process for the production of tizanidine
WO1987004433A1 (en) Preparation of 3-dimethylamino-7-methyl-1,2,4-benzotriazine-1-oxide and azapropazone
US20050119328A1 (en) Novel crysalline forms of tegaserod maleate
US6559319B2 (en) Synthesis of compounds useful in the manufacture of ketorolac
CA1175842A (en) 2,3-di-substituted-5,6-dihydroimidazo ¬2,1-b| thiazole, its salts, production thereof and anti- inflammatory agent containing the same
US20060128971A1 (en) Process for the preparation of the amorphous form of atorvastatin calcium salt
CN114736162B (zh) 脱羧肌肽结晶形态及其制备方法
Kambe et al. Thiocyanoacetate. IV. The Reaction of Ethyl Thiocyanoacetate with Aromatic Aldehydes in the Presence of Thioureas
US4632993A (en) Process for making 2-guanidino-4-(2-methyl-4-imidazolyl) thiazole dihydrobromide
IE912005A1 (en) "New process for the industrial preparation of 4-chloro 3-sulphamoyl-N-(2,3-dihydro-2-methyl-1H-indol-1- yl)- benzamide from 2,3-dihydro-2-methyl-1H-indole and hydrox ylamine-O-sulphonic acid"
AU769589B2 (en) Process for producing benzylamine compound
US20060025408A1 (en) Process for the preparation of crystalline form-1 of 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide
CN1134424C (zh) 应用质子惰性芳族溶剂制备噻二唑乙酰胺类衍生物化合物的方法
HU196386B (en) Process for production of derivatives of substituated ethan-diimid-amid
CN116283829B (zh) 一种具有噻二唑和咪唑结构的共晶体及其制备方法和应用
CA1117533A (en) Benzisothiazole-1,1-dioxides
CA1198734A (en) Three polyumorphic forms of 5-[3-(2,2,2- trifluoroethyl]guanidino)-pyrazol-1-yl)-valeramide
GB2165836A (en) Process for producing guanidinothiazole derivatives
KR920005828B1 (ko) 2-[(2-아미노에틸)-티오메틸]-5-디메틸아미노메틸 푸란의 산부가염의 제조방법
SU513626A3 (ru) Способ получени производных 4-(2-имидазолинил-2-амино)-2,1,3бензотиадиазола
CN87107492A (zh) 2-(1-戊基-3-胍基)-4-(2-甲基-4-咪唑基)噻唑及其二盐酸盐三水合物结晶的制备方法
GB2027700A (en) Process for the Preparation of Tricyclazole
SU1384197A3 (ru) Способ получени 1- @ 2-(5-(ди-метиламинометил)-2-(фурилметилтио)-этил) @ амино-1-(метиламино)-2-нитроэтилена или его гидрохлорида и способ получени дигидрохлорида 2-(2-аминоэтил)-тиометил-5-(диметиламинометил)-фурана или его моногидрохлорида

Legal Events

Date Code Title Description
MKEX Expiry