CA1310583C - Compositions polymerisables pouvant servir de support a des matieres actives etprocede de fabrication correspondant - Google Patents

Compositions polymerisables pouvant servir de support a des matieres actives etprocede de fabrication correspondant

Info

Publication number: CA1310583C
Authority: CA; Canada
Prior art keywords: beads; range; active substance; cross; delivery system
Prior art date: 1986-11-20
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

CA000546310A

Other languages

English (en)

Inventor

Richard Won

Martin Katz

Chung H. Cheng

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Heron Therapeutics LLC

Original Assignee

Advanced Polymer Systems Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-11-20

Filing date

1987-09-08

Publication date

1992-11-24

1987-09-08 Application filed by Advanced Polymer Systems Inc filed Critical Advanced Polymer Systems Inc

1992-11-24 Application granted granted Critical

1992-11-24 Publication of CA1310583C publication Critical patent/CA1310583C/fr

2009-11-24 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

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238000000034 method Methods 0.000 title claims abstract description 34
238000002360 preparation method Methods 0.000 title abstract description 20
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239000011148 porous material Substances 0.000 claims abstract description 70
239000013543 active substance Substances 0.000 claims abstract description 47
238000012384 transportation and delivery Methods 0.000 claims abstract description 46
238000004132 cross linking Methods 0.000 claims abstract description 30
239000000077 insect repellent Substances 0.000 claims abstract description 15
150000003431 steroids Chemical class 0.000 claims abstract description 15
239000003974 emollient agent Substances 0.000 claims abstract description 11
239000000126 substance Substances 0.000 claims description 37
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230000000475 sunscreen effect Effects 0.000 claims description 7
239000000516 sunscreening agent Substances 0.000 claims description 7
239000003470 adrenal cortex hormone Substances 0.000 claims description 2
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WBYWAXJHAXSJNI-UHFFFAOYSA-N cinnamic acid Chemical class OC(=O)C=CC1=CC=CC=C1 WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 claims 1
230000000717 retained effect Effects 0.000 claims 1
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239000003361 porogen Substances 0.000 abstract description 39
238000006116 polymerization reaction Methods 0.000 abstract description 15
238000010557 suspension polymerization reaction Methods 0.000 abstract description 3
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WYWZRNAHINYAEF-UHFFFAOYSA-N Padimate O Chemical compound CCCCC(CC)COC(=O)C1=CC=C(N(C)C)C=C1 WYWZRNAHINYAEF-UHFFFAOYSA-N 0.000 description 5
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DBCAQXHNJOFNGC-UHFFFAOYSA-N 4-bromo-1,1,1-trifluorobutane Chemical compound FC(F)(F)CCCBr DBCAQXHNJOFNGC-UHFFFAOYSA-N 0.000 description 4
239000004264 Petrolatum Substances 0.000 description 4
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MPMBRWOOISTHJV-UHFFFAOYSA-N but-1-enylbenzene Chemical compound CCC=CC1=CC=CC=C1 MPMBRWOOISTHJV-UHFFFAOYSA-N 0.000 description 4
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ALYNCZNDIQEVRV-UHFFFAOYSA-N 4-aminobenzoic acid Chemical compound NC1=CC=C(C(O)=O)C=C1 ALYNCZNDIQEVRV-UHFFFAOYSA-N 0.000 description 3
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VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 description 3
MMOXZBCLCQITDF-UHFFFAOYSA-N N,N-diethyl-m-toluamide Chemical compound CCN(CC)C(=O)C1=CC=CC(C)=C1 MMOXZBCLCQITDF-UHFFFAOYSA-N 0.000 description 3
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MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 3
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YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 3
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BWHLPLXXIDYSNW-UHFFFAOYSA-N ketorolac tromethamine Chemical compound OCC(N)(CO)CO.OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1 BWHLPLXXIDYSNW-UHFFFAOYSA-N 0.000 description 3
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KUDUQBURMYMBIJ-UHFFFAOYSA-N 2-prop-2-enoyloxyethyl prop-2-enoate Chemical compound C=CC(=O)OCCOC(=O)C=C KUDUQBURMYMBIJ-UHFFFAOYSA-N 0.000 description 2
ZGHFDIIVVIFNPS-UHFFFAOYSA-N 3-Methyl-3-buten-2-one Chemical compound CC(=C)C(C)=O ZGHFDIIVVIFNPS-UHFFFAOYSA-N 0.000 description 2
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NZHHDFRSEQSGLN-ZRDIBKRKSA-N tris(prop-2-enyl) (e)-prop-1-ene-1,2,3-tricarboxylate Chemical compound C=CCOC(=O)C\C(C(=O)OCC=C)=C/C(=O)OCC=C NZHHDFRSEQSGLN-ZRDIBKRKSA-N 0.000 description 1
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150000003738 xylenes Chemical class 0.000 description 1

Landscapes

Medicinal Preparation (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

CA000546310A 1986-11-20 1987-09-08 Compositions polymerisables pouvant servir de support a des matieres actives etprocede de fabrication correspondant Expired - Lifetime CA1310583C (fr)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US93261386A	1986-11-20	1986-11-20
US932,613		1986-11-20
US297387A	1987-01-13	1987-01-13
US002,973		1987-01-13

Publications (1)

Publication Number	Publication Date
CA1310583C true CA1310583C (fr)	1992-11-24

Family

ID=26671099

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA000546310A Expired - Lifetime CA1310583C (fr)	1986-11-20	1987-09-08	Compositions polymerisables pouvant servir de support a des matieres actives etprocede de fabrication correspondant

Country Status (1)

Country	Link
CA (1)	CA1310583C (fr)

1987
- 1987-09-08 CA CA000546310A patent/CA1310583C/fr not_active Expired - Lifetime

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Date	Code	Title	Description
2009-11-24	MKEX	Expiry

Publication	Publication Date	Title
EP0277211B1 (fr)	1994-06-01	Compositions porteuses polymeres et procedes pour leur preparation et utilisation
US5145675A (en)	1992-09-08	Two step method for preparation of controlled release formulations
EP0313380B1 (fr)	1993-12-29	Agrégat synthétique de mélanine
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