CA1331379C - Derives pregnane - Google Patents

Derives pregnane

Info

Publication number
CA1331379C
CA1331379C CA000578683A CA578683A CA1331379C CA 1331379 C CA1331379 C CA 1331379C CA 000578683 A CA000578683 A CA 000578683A CA 578683 A CA578683 A CA 578683A CA 1331379 C CA1331379 C CA 1331379C
Authority
CA
Canada
Prior art keywords
group
compound
configuration
alpha
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000578683A
Other languages
English (en)
Inventor
Jiro Tsuji
Takashi Takahashi
Masao Tsuji
Naoshi Nakagawa
Tetsuo Takigawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kuraray Co Ltd
Original Assignee
Kuraray Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE88902929T priority Critical patent/DE3881665T2/de
Priority to EP88902929A priority patent/EP0321572B1/fr
Priority to PCT/JP1988/000313 priority patent/WO1988007545A1/fr
Application filed by Kuraray Co Ltd filed Critical Kuraray Co Ltd
Priority to CA000578683A priority patent/CA1331379C/fr
Application granted granted Critical
Publication of CA1331379C publication Critical patent/CA1331379C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000578683A 1987-03-30 1988-09-28 Derives pregnane Expired - Fee Related CA1331379C (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
DE88902929T DE3881665T2 (de) 1987-03-30 1988-03-29 Pregnanabkömmlinge und verfahren zur herstellung.
EP88902929A EP0321572B1 (fr) 1987-03-30 1988-03-29 Derives de pregnane et procede de preparation
PCT/JP1988/000313 WO1988007545A1 (fr) 1987-03-30 1988-03-29 Derives de pregnane et procede de preparation
CA000578683A CA1331379C (fr) 1987-03-30 1988-09-28 Derives pregnane

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP7785087 1987-03-30
JP7785187 1987-03-30
JP7784987 1987-03-30
JP8058887 1987-03-31
JP8058987 1987-03-31
JP16819388 1988-07-05
CA000578683A CA1331379C (fr) 1987-03-30 1988-09-28 Derives pregnane

Publications (1)

Publication Number Publication Date
CA1331379C true CA1331379C (fr) 1994-08-09

Family

ID=27560935

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000578683A Expired - Fee Related CA1331379C (fr) 1987-03-30 1988-09-28 Derives pregnane

Country Status (1)

Country Link
CA (1) CA1331379C (fr)

Similar Documents

Publication Publication Date Title
US5929262A (en) Method for preparing 17α-acetoxy-11β-(4-N, N-dimethylaminophyl)-19-Norpregna-4,9-diene-3, 20-dione, intermediates useful in the method, and methods for the preparation of such intermediates
US4284577A (en) Novel vitamin D3 derivative and process for preparing the same
US4310467A (en) Process and intermediates for the synthesis of vitamin D3 metabolites
AU775831B2 (en) Process for preparing 17alpha-acetoxy-11beta-(4-N,N-(dimethylamino)phenyl)-21- methoxy-19-norpregna-4,9-diene-3,20-dione, intermediates useful in the process, and processes for preparing such intermediates
EP0095894A2 (fr) Dérivés de la 6-alpha-méthyle prednisolone
EP0321572B1 (fr) Derives de pregnane et procede de preparation
CA1331379C (fr) Derives pregnane
US4401596A (en) Novel 17-oxazoline-steroids
US5359055A (en) Pregnane derivatives and processes for production thereof
JPH0662558B2 (ja) １α，７，８−トリヒドロキシビタミンＤ化合物
US5112998A (en) Pregnane derivatives and processes for production thereof
EP0104387A1 (fr) Dérivés du 11-bêta-aryle-17-alpha-alcynyle-17-bêta-hydroxy-4,9(10)-estradiène-3-one, leur préparation et compositions pharmaceutiques les contenant
US6753414B2 (en) Process for preparing saponin compounds
US4038272A (en) Stereospecific syntheses of 24r,25- and 24s,25-dihydroxycholesterol and alkanoyl derivatives thereof
EP0051762A1 (fr) 11-Méthylène-delta 15-stéroides, procédé pour les préparer et compositions pharmaceutiques les contenant
JP2525049B2 (ja) プレグナン誘導体及びその製造方法
Kuo et al. Reductive transformation and cyclopropanation of mevinolin (6. alpha.-methylcompactin). Generation of chirality in the 1, 4-hydrostannation of a cyclic diene
GB1595020A (en) 3a-hydroxy steroid derivatives of the cholestane series
GB2036030A (en) Process for the manufacture of 1 3 -dihydroxy steroids
US4585591A (en) 17β-ethynylsteroids and process for preparing same
US4331802A (en) Organometallic reagents and their use in the synthesis of cardenolides and isocardenolides
EP0237397B1 (fr) Nouveaux stéroîdes 9(11) saturés substitués en position 10 par un radical comportant une triple liaison, leur procédé de préparation, leur application comme médicaments, les compositions pharmaceutiques les renfermant
Vorbrodt et al. Microbial degradation of 2α, 3α-dihydroxy-5α-cholestan-6-one by Mycobacterium vaccae
US4097477A (en) Steroid compounds and processes thereof
Le et al. Synthesis of 3. beta., 29-dihydroxystigmasta-5, 24 (28)(E)-dien-7-one

Legal Events

Date Code Title Description
MKLA Lapsed