CA1340604C - Methode pour preparer des composes 7-[2-(2-aminothiazol-4-y1)-2-hydroxyiminoacetamido]-3-cephemes - Google Patents

Methode pour preparer des composes 7-[2-(2-aminothiazol-4-y1)-2-hydroxyiminoacetamido]-3-cephemes

Info

Publication number
CA1340604C
CA1340604C CA000587693A CA587693A CA1340604C CA 1340604 C CA1340604 C CA 1340604C CA 000587693 A CA000587693 A CA 000587693A CA 587693 A CA587693 A CA 587693A CA 1340604 C CA1340604 C CA 1340604C
Authority
CA
Canada
Prior art keywords
salt
ester
aminothiazol
cephem
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000587693A
Other languages
English (en)
Inventor
Kazuo Sakane
Jiro Goto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of CA1340604C publication Critical patent/CA1340604C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
CA000587693A 1988-01-07 1989-01-06 Methode pour preparer des composes 7-[2-(2-aminothiazol-4-y1)-2-hydroxyiminoacetamido]-3-cephemes Expired - Lifetime CA1340604C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8800295 1988-01-07
GB888800295A GB8800295D0 (en) 1988-01-07 1988-01-07 Process for preparation of 7-(2-amino-thiazol-4-y)-2-hydroxyimino-acetanidol-3-cephem compounds

Publications (1)

Publication Number Publication Date
CA1340604C true CA1340604C (fr) 1999-06-22

Family

ID=10629612

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000587693A Expired - Lifetime CA1340604C (fr) 1988-01-07 1989-01-06 Methode pour preparer des composes 7-[2-(2-aminothiazol-4-y1)-2-hydroxyiminoacetamido]-3-cephemes

Country Status (5)

Country Link
JP (1) JP2600878B2 (fr)
KR (1) KR0140887B1 (fr)
CA (1) CA1340604C (fr)
ES (1) ES2013828A6 (fr)
GB (1) GB8800295D0 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7250508B2 (en) 2002-08-13 2007-07-31 Sandoz Ag Cefdinir intermediate

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100342600B1 (ko) * 2000-03-06 2002-07-04 한미정밀화학주식회사 신규한 티아졸 화합물 및 그의 제조 방법
KR100392409B1 (ko) * 2000-03-20 2003-07-22 한미정밀화학주식회사 신규한 티아졸 화합물을 이용한 세팔로스포린계항생물질의 제조 방법
JP2004149412A (ja) * 2000-06-21 2004-05-27 Fujisawa Pharmaceut Co Ltd ７−［２−（２−アミノチアゾール−４−イル）−２−低級アルコキシカルボニルメトキシイミノアセトアミド］−３−セフェム化合物の製造法
KR100451672B1 (ko) * 2001-06-05 2004-10-08 한미약품 주식회사 결정성 세프디니르 산부가염, 이의 제조방법 및 이를이용한 세프디니르의 제조방법
WO2004104010A1 (fr) * 2003-05-20 2004-12-02 Ranbaxy Laboratories Limited Forme cristalline de cefdinir
US7105659B2 (en) * 2003-06-02 2006-09-12 Aurobind - Pharma Ltd. Process for preparing cefdinir
GB0416380D0 (en) * 2004-07-22 2004-08-25 Sandoz Ag Organic compounds
GB0416379D0 (en) * 2004-07-22 2004-08-25 Sandoz Ag Organic compounds
CN113372292A (zh) * 2021-06-29 2021-09-10 山东昌邑四方医药化工有限公司 头孢他啶侧链酸的制备方法

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7250508B2 (en) 2002-08-13 2007-07-31 Sandoz Ag Cefdinir intermediate
US7825241B2 (en) 2002-08-13 2010-11-02 Sandoz Ag Cefdinir intermediate

Also Published As

Publication number Publication date
KR890011893A (ko) 1989-08-23
GB8800295D0 (en) 1988-02-10
JPH02790A (ja) 1990-01-05
ES2013828A6 (es) 1990-06-01
KR0140887B1 (ko) 1998-06-01
JP2600878B2 (ja) 1997-04-16

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Legal Events

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MKEX Expiry

Effective date: 20160622