CA1340850C - Compositions de nisine pour utilisationcomme bactericides ameliores a large spectre - Google Patents

Compositions de nisine pour utilisationcomme bactericides ameliores a large spectre

Info

Publication number: CA1340850C
Authority: CA; Canada
Prior art keywords: nisin; bactericide; group; bacteria; chelating agent
Prior art date: 1989-06-16
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

CA000603128A

Other languages

English (en)

Inventor

Peter Blackburn

June Polak

Sara-Ann Gusik

Stephen Rubino

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

AMBI Inc

Original Assignee

Applied Microbiology Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-16

Filing date

1989-06-16

Publication date

1999-12-14

1989-06-16 Application filed by Applied Microbiology Inc filed Critical Applied Microbiology Inc

1989-06-16 Priority to CA000603128A priority Critical patent/CA1340850C/fr

1999-12-14 Application granted granted Critical

1999-12-14 Publication of CA1340850C publication Critical patent/CA1340850C/fr

2016-12-14 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 104
239000003899 bactericide agent Substances 0.000 title claims abstract description 68
239000000203 mixture Substances 0.000 title claims abstract description 35
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DWPCPZJAHOETAG-IMJSIDKUSA-N L-lanthionine Chemical compound OC(=O)[C@@H](N)CSC[C@H](N)C(O)=O DWPCPZJAHOETAG-IMJSIDKUSA-N 0.000 claims abstract description 17
DWPCPZJAHOETAG-UHFFFAOYSA-N meso-lanthionine Natural products OC(=O)C(N)CSCC(N)C(O)=O DWPCPZJAHOETAG-UHFFFAOYSA-N 0.000 claims abstract description 17
KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 93
239000002738 chelating agent Substances 0.000 claims description 40
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RKLXDNHNLPUQRB-TVJUEJKUSA-N chembl564271 Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]2C(C)SC[C@H](N[C@@H](CC(N)=O)C(=O)NC(=O)[C@@H](NC2=O)CSC1C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NC(=C)C(=O)N[C@@H](CCCCN)C(O)=O)NC(=O)[C@H]1NC(=O)C(=C\C)/NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]2NC(=O)CNC(=O)[C@@H]3CCCN3C(=O)[C@@H](NC(=O)[C@H]3N[C@@H](CC(C)C)C(=O)NC(=O)C(=C)NC(=O)CC[C@H](NC(=O)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CC=4C5=CC=CC=C5NC=4)CSC3)C(O)=O)C(C)SC2)C(C)C)C(C)SC1)C1=CC=CC=C1 RKLXDNHNLPUQRB-TVJUEJKUSA-N 0.000 claims description 6
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239000007853 buffer solution Substances 0.000 description 1
239000001110 calcium chloride Substances 0.000 description 1
229910001628 calcium chloride Inorganic materials 0.000 description 1
235000011148 calcium chloride Nutrition 0.000 description 1
239000005018 casein Substances 0.000 description 1
BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
235000021240 caseins Nutrition 0.000 description 1
238000000576 coating method Methods 0.000 description 1
229920001436 collagen Polymers 0.000 description 1
230000001332 colony forming effect Effects 0.000 description 1
230000001010 compromised effect Effects 0.000 description 1
235000013399 edible fruits Nutrition 0.000 description 1
235000013601 eggs Nutrition 0.000 description 1
239000012894 fetal calf serum Substances 0.000 description 1
235000012041 food component Nutrition 0.000 description 1
239000005417 food ingredient Substances 0.000 description 1
238000009920 food preservation Methods 0.000 description 1
238000009472 formulation Methods 0.000 description 1
244000000058 gram-negative pathogen Species 0.000 description 1
244000052637 human pathogen Species 0.000 description 1
239000007943 implant Substances 0.000 description 1
208000015181 infectious disease Diseases 0.000 description 1
239000004615 ingredient Substances 0.000 description 1
239000003112 inhibitor Substances 0.000 description 1
230000000670 limiting effect Effects 0.000 description 1
239000007788 liquid Substances 0.000 description 1
239000006210 lotion Substances 0.000 description 1
229910052943 magnesium sulfate Inorganic materials 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
230000000813 microbial effect Effects 0.000 description 1
244000005700 microbiome Species 0.000 description 1
231100000404 nontoxic agent Toxicity 0.000 description 1
239000006916 nutrient agar Substances 0.000 description 1
239000002674 ointment Substances 0.000 description 1
238000004806 packaging method and process Methods 0.000 description 1
239000008188 pellet Substances 0.000 description 1
239000013612 plasmid Substances 0.000 description 1
229920000642 polymer Polymers 0.000 description 1
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230000003389 potentiating effect Effects 0.000 description 1
244000144977 poultry Species 0.000 description 1
235000013594 poultry meat Nutrition 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
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235000021067 refined food Nutrition 0.000 description 1
230000015227 regulation of liquid surface tension Effects 0.000 description 1
235000019512 sardine Nutrition 0.000 description 1
210000002966 serum Anatomy 0.000 description 1
239000011734 sodium Substances 0.000 description 1
235000019333 sodium laurylsulphate Nutrition 0.000 description 1
238000001228 spectrum Methods 0.000 description 1
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Gastroenterology & Hepatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

CA000603128A 1989-06-16 1989-06-16 Compositions de nisine pour utilisationcomme bactericides ameliores a large spectre Expired - Fee Related CA1340850C (fr)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
CA000603128A CA1340850C (fr)	1989-06-16	1989-06-16	Compositions de nisine pour utilisationcomme bactericides ameliores a large spectre

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CA000603128A CA1340850C (fr)	1989-06-16	1989-06-16	Compositions de nisine pour utilisationcomme bactericides ameliores a large spectre

Publications (1)

Publication Number	Publication Date
CA1340850C true CA1340850C (fr)	1999-12-14

Family

ID=33315137

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA000603128A Expired - Fee Related CA1340850C (fr)	1989-06-16	1989-06-16	Compositions de nisine pour utilisationcomme bactericides ameliores a large spectre

Country Status (1)

Country	Link
CA (1)	CA1340850C (fr)

1989
- 1989-06-16 CA CA000603128A patent/CA1340850C/fr not_active Expired - Fee Related

Legal Events

Date	Code	Title	Description
2015-01-26	MKLA	Lapsed	Effective date: 20141215

Publication	Publication Date	Title
US5260271A (en)	1993-11-09	Nisin compositions for use as enhanced broad range bactericides
US5135910A (en)	1992-08-04	Nisin compositions for use as enhanced, broad range bactericides
US5217950A (en)	1993-06-08	Nisin compositions for use as enhanced, broad range bactericides
EP0382814B1 (fr)	1994-02-16	Compositions de nisin utilises comme herbicide ameliore de champ d'action tres etendu
EP0424484B1 (fr)	1994-08-10	Nouvelles compositions de bacteriocine utilisees en tant que bactericides ameliores a large spectre, et procedes de prevention et de traitement d'infections
RU2092180C1 (ru)	1997-10-10	Антимикробная композиция
CA1340850C (fr)	1999-12-14	Compositions de nisine pour utilisationcomme bactericides ameliores a large spectre
KR0143423B1 (ko)	1998-07-01	향상된, 광범위 살균제로서 사용하기 위한 니신 조성물
PL163983B1 (pl)	1994-06-30	Środek bakteriobójczy
SK277796B6 (en)	1995-03-08	Agent containing nisine for using as bactericide with extended range