CA1341287C - Polypeptides derived from human papillomavirus, antibodies to said polypeptide and detection of human papillomavirus latent proteins - Google Patents

Polypeptides derived from human papillomavirus, antibodies to said polypeptide and detection of human papillomavirus latent proteins Download PDF

Info

Publication number
CA1341287C
CA1341287C CA000599671A CA599671A CA1341287C CA 1341287 C CA1341287 C CA 1341287C CA 000599671 A CA000599671 A CA 000599671A CA 599671 A CA599671 A CA 599671A CA 1341287 C CA1341287 C CA 1341287C
Authority
CA
Canada
Prior art keywords
polypeptide
amino acid
acid residue
protein
latent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000599671A
Other languages
English (en)
French (fr)
Inventor
Joakim Dillner
Richard A. Lerner
Richard Smith
D. Elliot Parks
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Institute filed Critical Scripps Research Institute
Application granted granted Critical
Publication of CA1341287C publication Critical patent/CA1341287C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—DNA viruses
    • C07K16/084—Papillomaviridae (F); Polyomaviridae (F), e.g. SV40, BK virus or JC virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA000599671A 1988-05-16 1989-05-15 Polypeptides derived from human papillomavirus, antibodies to said polypeptide and detection of human papillomavirus latent proteins Expired - Fee Related CA1341287C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US19440788A 1988-05-16 1988-05-16
US194,407 1988-05-16
US323,614 1989-03-13
US07/323,614 US5180806A (en) 1988-05-16 1989-03-13 Polypeptides and compositions of human papillomavirus latent proteins, diagnostic systems and methods

Publications (1)

Publication Number Publication Date
CA1341287C true CA1341287C (en) 2001-08-28

Family

ID=26889974

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000599671A Expired - Fee Related CA1341287C (en) 1988-05-16 1989-05-15 Polypeptides derived from human papillomavirus, antibodies to said polypeptide and detection of human papillomavirus latent proteins

Country Status (10)

Country Link
US (3) US5180806A (de)
EP (1) EP0344940B1 (de)
JP (1) JP2918904B2 (de)
AT (1) ATE130855T1 (de)
CA (1) CA1341287C (de)
DE (1) DE68924928T2 (de)
DK (1) DK173264B1 (de)
ES (1) ES2082775T4 (de)
GR (1) GR3018773T3 (de)
PT (1) PT90574B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110914295A (zh) * 2017-06-28 2020-03-24 里珍纳龙药品有限公司 抗人乳头瘤病毒(hpv)抗原结合蛋白及其使用方法

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5932412A (en) * 1990-05-11 1999-08-03 Euro-Diagnostica Ab Synthetic peptides in human papillomaviruses 1, 5, 6, 8, 11, 16, 18, 31, 33 and 56, useful in immunoassay for diagnostic purposes
SE9001705D0 (sv) * 1990-05-11 1990-05-11 Medscand Ab Saett foer diagnostik av virusbaerande tumoerer genom immunoassay
EP0510912B1 (de) * 1991-04-24 1998-01-07 Morinaga Milk Industry Co., Ltd. Antimikrobielles Peptid und antimikrobieller Wirkstoff
ES2193133T3 (es) * 1991-07-13 2003-11-01 Dade Behring Marburg Gmbh Uso de peptidos derivados de los genes e6 y e7 de hpv-16 para fines.
DE4123760C2 (de) * 1991-07-18 2000-01-20 Dade Behring Marburg Gmbh Seroreaktive Bereiche auf den HPV 16 Proteinen E1 und E2
US5437951A (en) * 1992-09-03 1995-08-01 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
GB9306731D0 (en) * 1993-03-31 1993-05-26 Cancer Res Campaign Tech Vaccines
DE19819476C1 (de) * 1998-04-30 2000-01-05 Deutsches Krebsforsch Polypeptid mit immunogenen Eigenschaften und veränderten biologischen Funktionen eines Proteins
GB2353581B (en) 1999-08-27 2003-06-11 Uponor Ltd Swage lining
US7026443B1 (en) 1999-12-10 2006-04-11 Epimmune Inc. Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions
JP2001172200A (ja) * 1999-12-17 2001-06-26 Meneki Seibutsu Kenkyusho:Kk ヒトナプシンａに対する抗体およびこれを用いる医薬
CN1433428A (zh) * 2000-04-05 2003-07-30 冲击诊断公司 辨别人乳头瘤病毒的免疫学方法
EP1288292A1 (de) * 2001-08-31 2003-03-05 Leids Universitair Medisch Centrum Lange Peptiden die 22-40 Aminosäuren enthalten und die eine immunspezifische Immunantwort induzieren
AU2002219711B8 (en) * 2000-12-08 2006-03-02 Academisch Ziekenhuis Leiden Long peptides of 22-45 amino acid residues that induce and/or enhance antigen specific immune responses
EP1352241A1 (de) * 2000-12-21 2003-10-15 Biosignature Diagnostics, Inc. Multiplex-absorptionstechnologie
US6933123B2 (en) 2001-04-05 2005-08-23 Yao Xiong Hu Peptides from the E2, E6, and E7 proteins of human papilloma viruses 16 and 18 for detecting and/or diagnosing cervical and other human papillomavirus associated cancers
GB2379220A (en) * 2001-08-13 2003-03-05 Univ York Antibodies to HPV E2 protein
CA2536735C (en) * 2003-09-05 2013-01-22 Genencor International, Inc. Methods for determining cd8+ t-cell epitopes
WO2005063286A1 (en) * 2003-12-23 2005-07-14 Arbor Vita Corporation Antibodies for oncogenic strains of hpv and methods of their use
AU2005222776A1 (en) * 2003-12-31 2005-09-29 Genimmune N.V. Inducing cellular immune responses to human papillomavirus using peptide and nucleic acid compositions
US7732166B2 (en) * 2005-11-15 2010-06-08 Oncohealth Corporation Detection method for human pappilomavirus (HPV) and its application in cervical cancer
US7972776B2 (en) * 2005-11-15 2011-07-05 Oncohealth Corporation Protein chips for HPV detection
US8051950B2 (en) * 2006-08-03 2011-11-08 Glacier Bay, Inc. System for reducing acoustic energy
US8968995B2 (en) * 2008-11-12 2015-03-03 Oncohealth Corp. Detection, screening, and diagnosis of HPV-associated cancers
WO2010129821A1 (en) 2009-05-07 2010-11-11 Oncohealth Corporation Identification of high grade or ≥cin2 for early stages and late stages detection, screening, and diagnosis of human papillomavirus (hpv) and hpv-associated cancers
US8278056B2 (en) * 2008-06-13 2012-10-02 Oncohealth Corp. Detection of early stages and late stages HPV infection
MX2009012922A (es) * 2007-05-31 2010-07-05 Academisch Ziekenhuis Leiden H Vacunacion intradermica de un peptido del virus del papiloma humano.
ES2641892T3 (es) * 2009-08-26 2017-11-14 Selecta Biosciences, Inc. Composiciones que inducen la ayuda de las células T
WO2011085231A2 (en) * 2010-01-08 2011-07-14 Selecta Biosciences, Inc. Synthetic virus-like particles conjugated to human papillomavirus capsid peptides for use as vaccines
JP5819851B2 (ja) 2010-01-08 2015-11-24 オンコヘルス コーポレーション Ｈｐｖ関連の癌の治療及びスクリーニングのための細胞に基づいた高処理能力ｈｐｖ免疫アッセイ
CN103940993A (zh) * 2013-01-23 2014-07-23 艾托金生物医药（苏州）有限公司 用于检测抗人乳头瘤病毒抗体的抗原及试剂盒和应用
WO2019145792A1 (en) * 2018-01-24 2019-08-01 The Council Of The Queensland Institute Of Medical Research Hpv immunotherapy
BR112021001992A2 (pt) 2018-08-02 2021-05-04 The Board Of Regents Of The University Of Texas System efeito adjuvante do agonista tlr1/2 diprovocim sinergiza com anticorpos inibidores de checkpoint para eliminar doença
US11938182B2 (en) 2020-03-26 2024-03-26 Provectus Pharmatech, Inc. Halogenated xanthenes as vaccine adjuvants
EP4103283A4 (de) 2020-03-26 2024-02-28 Provectus Pharmatech, Inc. Neue verwendungen von halogenierten xanthenen in der onkologie und virologie
CN112920267B (zh) * 2021-03-09 2021-08-13 北京康乐卫士生物技术股份有限公司 一种抗人乳头瘤病毒31型的单克隆中和抗体及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4748109A (en) * 1983-07-01 1988-05-31 Baird Phillip J Assay method and reagent to determine antibodies to papillomavirus virions
LU85462A1 (fr) * 1984-07-11 1986-02-12 Univ Louvain Nouvelles compositions polymeres,procedes pour leur production et leurs applications
US4777239A (en) * 1986-07-10 1988-10-11 The Board Of Trustees Of The Leland Stanford Junior University Diagnostic peptides of human papilloma virus

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110914295A (zh) * 2017-06-28 2020-03-24 里珍纳龙药品有限公司 抗人乳头瘤病毒(hpv)抗原结合蛋白及其使用方法
CN110914295B (zh) * 2017-06-28 2024-08-09 里珍纳龙药品有限公司 抗人乳头瘤病毒(hpv)抗原结合蛋白及其使用方法

Also Published As

Publication number Publication date
ES2082775T3 (es) 1996-04-01
PT90574B (pt) 1994-09-30
DK234789D0 (da) 1989-05-12
US5401627A (en) 1995-03-28
EP0344940A2 (de) 1989-12-06
EP0344940A3 (de) 1991-11-13
JP2918904B2 (ja) 1999-07-12
GR3018773T3 (en) 1996-04-30
DE68924928D1 (de) 1996-01-11
DE68924928T2 (de) 1996-10-17
ES2082775T4 (es) 1996-08-01
US5180806A (en) 1993-01-19
ATE130855T1 (de) 1995-12-15
EP0344940B1 (de) 1995-11-29
PT90574A (pt) 1989-11-30
US5486453A (en) 1996-01-23
JPH0296593A (ja) 1990-04-09
DK173264B1 (da) 2000-05-29
DK234789A (da) 1989-11-17

Similar Documents

Publication Publication Date Title
CA1341287C (en) Polypeptides derived from human papillomavirus, antibodies to said polypeptide and detection of human papillomavirus latent proteins
JP3366350B2 (ja) Ｈｐｖ‐１６ ｅ６およびｅ７‐遺伝子由来ペプチドの、診断のための使用
US5538865A (en) Hepatitis C virus epitopes
JP4365440B2 (ja) エプスタイン−バールウイルスに関連するペプチド及び核酸配列
EP0162533B1 (de) Nachweis von menschlichem Cytomegalovirus-spezifischem IgM
CA1292839C (en) Synthetic polypeptides and antibodies related to epstein-barr virus nuclear antigen
US5629146A (en) Method for detection of human papillomavirus (HPV) for diagnostic purposes
Dillner et al. Mapping of linear epitopes of human papillomavirus type 16: the L1 and L2 open reading frames
JPS63225398A (ja) エプスタイン・バーウイルス初期抗原（拡散）に関連する合成ポリペプチドおよび抗体
JP4612071B2 (ja) エプスタイン−バールウイルスペプチド及び該ペプチドに対する抗体
JPS62502704A (ja) 立体配座−独立並びに立体配座依存決定基を有するタンパク抗原
US4743562A (en) Purified human cytomegalovirus protein
KR102000479B1 (ko) 항인간 노로바이러스 gii 항체
US20070166699A1 (en) Combination of anti-hpv-16 and 18 antibodies and uses thereof
Cheng et al. Detection of the readthrough protein of barley yellow dwarf virus
CA1339363C (en) Monoclonal antibodies to specific antigenic regions of the human immunodeficiency virus and methods for use
AU628337B2 (en) Antibodies to human papillomavirus latent proteins, diagnostic systems and methods
WO1990004176A1 (en) THE RECEPTOR BINDING REGION OF EBVgp350
US5314800A (en) Purified human cytomegalovirus protein
Stinski et al. Antibody to the type 5 adenovirus hexon polypeptide: detection of nascent polypeptides in the cytoplasm of infected KB cells
JPH02219591A (ja) 抗ヒトパピローマウイルスモノクローナル抗体、それを産生するハイブリドーマ並びに該抗体の製造方法
CA1338441C (en) Expression of immunologically active proteins of human .beta.-lympho tropic virus
CN119798384B (zh) 一种特异型检测轮状病毒的单克隆抗体及其应用
HK40048332B (en) Method and antibody for detecting hbcag
CN121991184A (zh) 一种特异型检测轮状病毒的单克隆抗体及其应用

Legal Events

Date Code Title Description
MKLA Lapsed