CA2004571A1 - Administration transdermique et intranasale de peptides inhibiteurs de la renine - Google Patents

Administration transdermique et intranasale de peptides inhibiteurs de la renine

Info

Publication number
CA2004571A1
CA2004571A1 CA002004571A CA2004571A CA2004571A1 CA 2004571 A1 CA2004571 A1 CA 2004571A1 CA 002004571 A CA002004571 A CA 002004571A CA 2004571 A CA2004571 A CA 2004571A CA 2004571 A1 CA2004571 A1 CA 2004571A1
Authority
CA
Canada
Prior art keywords
ile
phe
pro
mehis
lva
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002004571A
Other languages
English (en)
Inventor
Donald T. Pals
Lawrence S. Olanoff
Judy A. Lawson
Richard E. Gibson
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of CA2004571A1 publication Critical patent/CA2004571A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/553Renin inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
CA002004571A 1988-12-22 1989-12-05 Administration transdermique et intranasale de peptides inhibiteurs de la renine Abandoned CA2004571A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28853188A 1988-12-22 1988-12-22
US07/288,531 1988-12-22

Publications (1)

Publication Number Publication Date
CA2004571A1 true CA2004571A1 (fr) 1990-06-22

Family

ID=23107533

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002004571A Abandoned CA2004571A1 (fr) 1988-12-22 1989-12-05 Administration transdermique et intranasale de peptides inhibiteurs de la renine

Country Status (5)

Country Link
EP (1) EP0449943A1 (fr)
JP (1) JPH04502458A (fr)
AU (1) AU4664089A (fr)
CA (1) CA2004571A1 (fr)
WO (1) WO1990006761A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19819652A1 (de) * 1998-05-02 1999-11-11 Lohmann Therapie Syst Lts Therapeutisches System zur topischen oder transmucosalen Applikation wenigstens eines Pflege- oder Wirkstoffs auf bzw. durch die Nasenschleimhaut sowie Verfahren zur Applikation des Systems

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI88400C (fi) * 1984-08-06 1993-05-10 Upjohn Co Foerfarande foer framstaellning av renin inhiberande peptider
US4906613A (en) * 1985-11-05 1990-03-06 Schering Corporation Antiglaucoma compositions and methods
US4758584A (en) * 1987-02-05 1988-07-19 Ciba-Geigy Corporation Antihypertensive 5-amino-4-hydroxyvaleryl derivatives substituted by sulphur-containing groups

Also Published As

Publication number Publication date
AU4664089A (en) 1990-07-10
JPH04502458A (ja) 1992-05-07
WO1990006761A1 (fr) 1990-06-28
EP0449943A1 (fr) 1991-10-09

Similar Documents

Publication Publication Date Title
JP3174323B2 (ja) 毛髪成長を刺激するための金属―ペプチド組成物及び方法
EP0528891B1 (fr) Procede servant a augmenter la permeabilite de la barriere hemato-encephalique
US6780848B2 (en) Use of GPE to protect glial cells or non-dopaminergic cells from death from neural injury or disease
JPH05505808A (ja) 創傷の治癒を促進するためへの銅(2)含有化合物の使用
US6821953B1 (en) Methods for treating and preventing damage to mucosal tissue
KR880005148A (ko) 아미노산 유도체
GB2112641A (en) The use of peptides as medicaments
US5482930A (en) Anti-inflammatory composition and method with des-Tyr dynorphin and analogues
JP2001500876A (ja) 液体形態の改良された安定性を有するコルチコトロピン放出因子の医薬製剤
US4684624A (en) Method of treating cerebral ischemia
JP4860096B2 (ja) 鎮痛性ペプチドを含んでなる薬剤組成物
NZ265949A (en) Transdermal therapeutic system; comprises an indole derivative as an active ingredient
JPH10502328A (ja) 蛋白質をその中にカプセル化含有するリポソーム、並びにその調製方法、及びそれを含有する薬剤、整形剤
WO2002016408A2 (fr) Analogues de gpe
JP2003514920A (ja) 抗血管新生活性を有するn−アルキル化ペプチド
KR100466757B1 (ko) 생체에 펩티드성 약물을 유입시키기 위한 국소 제제
DE60017793T2 (de) Verfahren zur vorbeugung und behandlung von beschädigungen des schleimhautgewebes
WO1990006761A1 (fr) Administration transdermique et intranasale de peptides inhibiteurs de renine
EP2487185A1 (fr) Hexapeptide ayant une activité améliorée pour la réparation de l'ADN cellulaire de cellules dermiques
IL112183A (en) Use of bradykinin antagonists for the preparation of medicaments for the treatment of virus diseases
US7112570B2 (en) GPE analogs
HK1006283B (en) Pharmaceutical compositions containing acth fragments for the therapy of shock conditions and of respiratory and cardiocirculatory insufficiencies
EP0147194B1 (fr) Compositions pour le traitement de l'ischémie cérébrale
WO1990006743A1 (fr) Procede de retablissement de la croissance des cheveux
WO2002011784A2 (fr) Supports et compositions pharmaceutiques pour administration transdermique de medicaments

Legal Events

Date Code Title Description
FZDE Discontinued