CA2005782A1 - Apparatus and method for the self-levelling of liquid in a container and/or for the introduction of bubble-free liquid to a container - Google Patents

Apparatus and method for the self-levelling of liquid in a container and/or for the introduction of bubble-free liquid to a container

Info

Publication number: CA2005782A1
Authority: CA; Canada
Prior art keywords: liquid; container; supply chamber; level; bubble
Prior art date: 1989-05-30
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002005782A

Other languages

English (en)

French (fr)

Inventor

Malcolm G. Bock

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bayer Corp

Original Assignee

Technicon Instruments Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-05-30

Filing date

1989-12-18

Publication date

1990-11-30

1989-12-18 Application filed by Technicon Instruments Corp filed Critical Technicon Instruments Corp

1990-11-30 Publication of CA2005782A1 publication Critical patent/CA2005782A1/en

Status Abandoned legal-status Critical Current

Links

239000007788 liquid Substances 0.000 title claims abstract description 554
238000000034 method Methods 0.000 title claims abstract description 59
230000037361 pathway Effects 0.000 claims abstract description 68
230000005499 meniscus Effects 0.000 claims abstract description 36
238000002955 isolation Methods 0.000 claims abstract description 12
230000009471 action Effects 0.000 claims description 19
239000000463 material Substances 0.000 claims description 17
239000004033 plastic Substances 0.000 claims description 4
229920003023 plastic Polymers 0.000 claims description 4
230000015572 biosynthetic process Effects 0.000 claims description 3
239000004094 surface-active agent Substances 0.000 claims description 2
230000014759 maintenance of location Effects 0.000 claims 5
239000011521 glass Substances 0.000 claims 1
239000011213 glass-filled polymer Substances 0.000 claims 1
239000000523 sample Substances 0.000 description 60
150000002500 ions Chemical class 0.000 description 25
238000004458 analytical method Methods 0.000 description 19
241001237728 Precis Species 0.000 description 14
239000003570 air Substances 0.000 description 14
239000002245 particle Substances 0.000 description 14
238000009736 wetting Methods 0.000 description 9
239000003153 chemical reaction reagent Substances 0.000 description 8
230000008859 change Effects 0.000 description 6
238000004519 manufacturing process Methods 0.000 description 6
230000008901 benefit Effects 0.000 description 5
239000007787 solid Substances 0.000 description 3
241000894007 species Species 0.000 description 3
241000534944 Thia Species 0.000 description 2
230000002411 adverse Effects 0.000 description 2
239000012080 ambient air Substances 0.000 description 2
230000001419 dependent effect Effects 0.000 description 2
238000001704 evaporation Methods 0.000 description 2
230000008020 evaporation Effects 0.000 description 2
230000005484 gravity Effects 0.000 description 2
239000002674 ointment Substances 0.000 description 2
230000000737 periodic effect Effects 0.000 description 2
230000009467 reduction Effects 0.000 description 2
HLCHESOMJVGDSJ-UHFFFAOYSA-N thiq Chemical compound C1=CC(Cl)=CC=C1CC(C(=O)N1CCC(CN2N=CN=C2)(CC1)C1CCCCC1)NC(=O)C1NCC2=CC=CC=C2C1 HLCHESOMJVGDSJ-UHFFFAOYSA-N 0.000 description 2
BHMLFPOTZYRDKA-IRXDYDNUSA-N (2s)-2-[(s)-(2-iodophenoxy)-phenylmethyl]morpholine Chemical compound IC1=CC=CC=C1O[C@@H](C=1C=CC=CC=1)[C@H]1OCCNC1 BHMLFPOTZYRDKA-IRXDYDNUSA-N 0.000 description 1
SUBDBMMJDZJVOS-UHFFFAOYSA-N 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Chemical compound N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-UHFFFAOYSA-N 0.000 description 1
241000408452 Acrosathe Species 0.000 description 1
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239000004215 Carbon black (E152) Substances 0.000 description 1
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241000168096 Glareolidae Species 0.000 description 1
101100313003 Rattus norvegicus Tanc1 gene Proteins 0.000 description 1
XDXHAEQXIBQUEZ-UHFFFAOYSA-N Ropinirole hydrochloride Chemical compound Cl.CCCN(CCC)CCC1=CC=CC2=C1CC(=O)N2 XDXHAEQXIBQUEZ-UHFFFAOYSA-N 0.000 description 1
241000950638 Symphysodon discus Species 0.000 description 1
LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 1
230000001133 acceleration Effects 0.000 description 1
SCJNCDSAIRBRIA-DOFZRALJSA-N arachidonyl-2'-chloroethylamide Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCCl SCJNCDSAIRBRIA-DOFZRALJSA-N 0.000 description 1
230000000712 assembly Effects 0.000 description 1
238000000429 assembly Methods 0.000 description 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
239000008280 blood Substances 0.000 description 1
210000004369 blood Anatomy 0.000 description 1
235000015115 caffè latte Nutrition 0.000 description 1
239000012611 container material Substances 0.000 description 1
239000000356 contaminant Substances 0.000 description 1
238000011109 contamination Methods 0.000 description 1
JXSJBGJIGXNWCI-UHFFFAOYSA-N diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate Chemical compound CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC JXSJBGJIGXNWCI-UHFFFAOYSA-N 0.000 description 1
230000009977 dual effect Effects 0.000 description 1
230000000694 effects Effects 0.000 description 1
238000001914 filtration Methods 0.000 description 1
239000007789 gas Substances 0.000 description 1
ZNNLBTZKUZBEKO-UHFFFAOYSA-N glyburide Chemical compound COC1=CC=C(Cl)C=C1C(=O)NCCC1=CC=C(S(=O)(=O)NC(=O)NC2CCCCC2)C=C1 ZNNLBTZKUZBEKO-UHFFFAOYSA-N 0.000 description 1
229930195733 hydrocarbon Natural products 0.000 description 1
150000002430 hydrocarbons Chemical class 0.000 description 1
230000002209 hydrophobic effect Effects 0.000 description 1
239000012678 infectious agent Substances 0.000 description 1
230000002401 inhibitory effect Effects 0.000 description 1
238000002347 injection Methods 0.000 description 1
239000007924 injection Substances 0.000 description 1
230000002452 interceptive effect Effects 0.000 description 1
210000003141 lower extremity Anatomy 0.000 description 1
229940061319 ovide Drugs 0.000 description 1
239000001301 oxygen Substances 0.000 description 1
229910052760 oxygen Inorganic materials 0.000 description 1
239000004800 polyvinyl chloride Substances 0.000 description 1
229920000915 polyvinyl chloride Polymers 0.000 description 1
BALXUFOVQVENIU-KXNXZCPBSA-N pseudoephedrine hydrochloride Chemical compound [H+].[Cl-].CN[C@@H](C)[C@@H](O)C1=CC=CC=C1 BALXUFOVQVENIU-KXNXZCPBSA-N 0.000 description 1
238000005086 pumping Methods 0.000 description 1
230000000717 retained effect Effects 0.000 description 1
235000002020 sage Nutrition 0.000 description 1
239000000126 substance Substances 0.000 description 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
- G01F23/00—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm
- G01F23/0053—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm with over-flow pipes
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0289—Apparatus for withdrawing or distributing predetermined quantities of fluid
- B01L3/0293—Apparatus for withdrawing or distributing predetermined quantities of fluid for liquids
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0605—Metering of fluids
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0642—Filling fluids into wells by specific techniques
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/087—Multiple sequential chambers
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Analytical Chemistry (AREA)
Clinical Laboratory Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Fluid Mechanics (AREA)
Physics & Mathematics (AREA)
General Physics & Mathematics (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Sampling And Sample Adjustment (AREA)
Automatic Analysis And Handling Materials Therefor (AREA)
Details Of Rigid Or Semi-Rigid Containers (AREA)
Physical Or Chemical Processes And Apparatus (AREA)
Control Of Non-Electrical Variables (AREA)

CA002005782A 1989-05-30 1989-12-18 Apparatus and method for the self-levelling of liquid in a container and/or for the introduction of bubble-free liquid to a container Abandoned CA2005782A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
USPCT/US89/02345		1989-05-30
PCT/US1989/002345 WO1990015333A1 (en)	1989-05-30	1989-05-30	Apparatus and method for the self-levelling of liquid in a container

Publications (1)

Publication Number	Publication Date
CA2005782A1 true CA2005782A1 (en)	1990-11-30

Family

ID=22215049

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002005782A Abandoned CA2005782A1 (en)	1989-05-30	1989-12-18	Apparatus and method for the self-levelling of liquid in a container and/or for the introduction of bubble-free liquid to a container

Country Status (8)

Country	Link
EP (1)	EP0474630A4 (da)
JP (1)	JPH04505048A (da)
AU (1)	AU645961B2 (da)
CA (1)	CA2005782A1 (da)
DK (1)	DK193891D0 (da)
ES (1)	ES2017885A6 (da)
IL (1)	IL92005A0 (da)
WO (1)	WO1990015333A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5234813A (en) *	1989-05-17	1993-08-10	Actimed Laboratories, Inc.	Method and device for metering of fluid samples and detection of analytes therein
JP2583196Y2 (ja) *	1992-11-07	1998-10-15	株式会社堀場製作所	黒鉛るつぼ
JP3619933B2 (ja) *	2000-03-02	2005-02-16	アークレイ株式会社	遠心分離用容器
AU2003236896A1 (en) *	2002-05-31	2003-12-19	Cancer Research Technology Ltd	Substrate for holding an array of experimental samples
CN110068558A (zh) *	2018-01-24	2019-07-30	思纳福(北京)医疗科技有限公司	微液滴容器

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US1144525A (en) *	1913-12-09	1915-06-29	William F Rogers	Diffusing apparatus.
US1235316A (en) *	1916-05-22	1917-07-31	Charles H Henderson	Automatic siphon-regulator.
US1574149A (en) *	1924-01-24	1926-02-23	Hompes Henry	Cream divider
US1564430A (en) *	1925-01-30	1925-12-08	Walter J Maddrell	Device for maintaining liquid levels
US2356013A (en) *	1943-08-03	1944-08-15	Rossi Irving	Continuous casting of metals
US2461334A (en) *	1944-12-01	1949-02-08	Servel Inc	Liquid treating unit
US2884942A (en) *	1957-05-06	1959-05-05	Jersey Prod Res Co	Apparatus for use in corrosion inhibitor injection
US3415267A (en) *	1966-08-31	1968-12-10	Cory Corp	Liquid supply apparatus
US3589385A (en) *	1969-02-07	1971-06-29	Cory Corp	Vented hot water supply apparatus
DE2200385A1 (de) *	1972-01-05	1973-07-12	Gerstel Eberhard	Ueberlaufgefaess fuer selbsttaetigen fraktionensammler
US4515753A (en) *	1982-11-15	1985-05-07	Technicon Instruments Corporation	Integral reagent dispenser
JPH0658374B2 (ja) *	1985-07-23	1994-08-03	株式会社東芝	反応槽の恒温流体オ−バ−フロ−方法
CA1292176C (en) *	1985-09-18	1991-11-19	Joel M. Blatt	Volume metering capillary gap device for applying a liquid sample onto a reactive surface
US4774057A (en) *	1985-10-25	1988-09-27	Technicon Instruments Corporation	Dual liquid dispenser package
US4758409A (en) *	1986-07-10	1988-07-19	Techicon Instruments Corporation	Microsample cup
DE8715505U1 (de) *	1987-11-23	1988-02-18	LMB Medizin Technik GmbH, 8059 Oberding	Reaktionsgefäß zur Untersuchung flüssiger Proben im Mikroliterbereich

1989
- 1989-05-30 WO PCT/US1989/002345 patent/WO1990015333A1/en not_active Ceased
- 1989-05-30 AU AU37429/89A patent/AU645961B2/en not_active Expired - Fee Related
- 1989-05-30 EP EP19890906603 patent/EP0474630A4/en not_active Withdrawn
- 1989-05-30 JP JP1502734A patent/JPH04505048A/ja active Pending
- 1989-10-16 IL IL92005A patent/IL92005A0/xx not_active IP Right Cessation
- 1989-12-07 ES ES898904161A patent/ES2017885A6/es not_active Expired - Lifetime
- 1989-12-18 CA CA002005782A patent/CA2005782A1/en not_active Abandoned
1991
- 1991-11-29 DK DK911938A patent/DK193891D0/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU645961B2 (en)	1994-02-03
ES2017885A6 (es)	1991-03-01
DK193891A (da)	1991-11-29
DK193891D0 (da)	1991-11-29
AU3742989A (en)	1991-01-07
EP0474630A1 (en)	1992-03-18
WO1990015333A1 (en)	1990-12-13
EP0474630A4 (en)	1992-07-22
IL92005A0 (en)	1990-07-12
JPH04505048A (ja)	1992-09-03

Legal Events

Date	Code	Title	Description
1993-09-29	EEER	Examination request
1995-06-18	FZDE	Discontinued

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