CA2007785A1 - 1-[3-(2-hydroxy-3-alkylaminopropoxy)-2-thienyl] -2-thienyl]-3-phenyl-1-propanones et procede de preparation - Google Patents

1-[3-(2-hydroxy-3-alkylaminopropoxy)-2-thienyl] -2-thienyl]-3-phenyl-1-propanones et procede de preparation

Info

Publication number
CA2007785A1
CA2007785A1 CA2007785A CA2007785A CA2007785A1 CA 2007785 A1 CA2007785 A1 CA 2007785A1 CA 2007785 A CA2007785 A CA 2007785A CA 2007785 A CA2007785 A CA 2007785A CA 2007785 A1 CA2007785 A1 CA 2007785A1
Authority
CA
Canada
Prior art keywords
alkylaminopropoxy
thienyl
hydroxy
phenyl
propanones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2007785A
Other languages
English (en)
Other versions
CA2007785C (fr
Inventor
Dieter Binder
Gerhard Greier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laevosan GmbH and Co KG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2007785A1 publication Critical patent/CA2007785A1/fr
Application granted granted Critical
Publication of CA2007785C publication Critical patent/CA2007785C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/32—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
CA002007785A 1989-01-24 1990-01-15 1-[3-(2-hydroxy-3-alkylaminopropoxy)-2-thienyl] -2-thienyl]-3-phenyl-1-propanones et procede de preparation Expired - Fee Related CA2007785C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ATA130/89 1989-01-24
AT130/89A AT392967B (de) 1989-01-24 1989-01-24 Neue 1-(3-(2-hydroxy-3-alkylaminopropoxy)-2- thienyl)-3-phenyl-1-propanone und verfahren zu deren herstellung

Publications (2)

Publication Number Publication Date
CA2007785A1 true CA2007785A1 (fr) 1990-07-24
CA2007785C CA2007785C (fr) 1996-09-03

Family

ID=3482324

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002007785A Expired - Fee Related CA2007785C (fr) 1989-01-24 1990-01-15 1-[3-(2-hydroxy-3-alkylaminopropoxy)-2-thienyl] -2-thienyl]-3-phenyl-1-propanones et procede de preparation

Country Status (9)

Country Link
US (1) US4994484A (fr)
EP (1) EP0381661B1 (fr)
JP (1) JPH02233677A (fr)
AT (1) AT392967B (fr)
CA (1) CA2007785C (fr)
DE (1) DE59009107D1 (fr)
DK (1) DK0381661T3 (fr)
ES (1) ES2075191T3 (fr)
GR (1) GR3017119T3 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3907512C2 (de) * 1989-03-08 1997-08-14 Laevosan Gmbh & Co Kg Neue Aryloxy-alkylamine, deren Herstellung und diese enthaltende Arzneimittel
US5891885A (en) * 1996-10-09 1999-04-06 Algos Pharmaceutical Corporation Method for treating migraine
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en) 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1266119B (de) * 1963-03-19 1968-04-11 Waertsilae Yhtymae O Y Waertsi Trockenzylinder fuer Papiermaschinen
US3614983A (en) * 1969-04-09 1971-10-26 Johnson Corp Internal small bore roll syphon
AT369739B (de) * 1980-11-28 1983-01-25 Laevosan Gmbh & Co Kg Verfahren zur herstellung neuer 1-(3-(2-hydroxy-3alkylaminopropoxy)-2-thienyl)-3-phenyl-1- propanone und ihrer saeureadditionssalze
DE3316155A1 (de) * 1983-05-03 1984-11-08 Helopharm W. Petrik & Co Kg, 1000 Berlin 2-(2'hydroxy-3'-(1,1-dimethylpropylamino)-propoxy)-1-thienylpropiophenon, seine saeureadditionssalze, verfahren zu seiner herstellung und arzneimittel
JPS62178585A (ja) * 1986-01-29 1987-08-05 レフオ−サン−ゲゼルシヤフト　エム・ベ−・ハ− １−〔３−（２−ヒドロキシ−３−アルキルアミノプロポキシ）−２−チエニル〕−３−フエニル−１−プロパノン及びそれらの酸付加塩並びにそれらの製造法及びそれらを含む薬学的組成物
ATE63550T1 (de) * 1986-10-29 1991-06-15 Binder Dieter Neue 1-/ 3-(2-dialkylaminoaethoxy)-2-thienyl/-3phenyl-1-propanone und ihre saeureadditionssalze und verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Also Published As

Publication number Publication date
ATA13089A (de) 1990-12-15
ES2075191T3 (es) 1995-10-01
EP0381661A1 (fr) 1990-08-08
CA2007785C (fr) 1996-09-03
DE59009107D1 (de) 1995-06-29
DK0381661T3 (da) 1995-10-09
AT392967B (de) 1991-07-25
GR3017119T3 (en) 1995-11-30
US4994484A (en) 1991-02-19
EP0381661B1 (fr) 1995-05-24
JPH02233677A (ja) 1990-09-17

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Legal Events

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