CA2009074A1 - Ameliorations concernant les derives de guanidine - Google Patents
Ameliorations concernant les derives de guanidineInfo
- Publication number
- CA2009074A1 CA2009074A1 CA2009074A CA2009074A CA2009074A1 CA 2009074 A1 CA2009074 A1 CA 2009074A1 CA 2009074 A CA2009074 A CA 2009074A CA 2009074 A CA2009074 A CA 2009074A CA 2009074 A1 CA2009074 A1 CA 2009074A1
- Authority
- CA
- Canada
- Prior art keywords
- relating
- guanidine derivatives
- compound
- trimethylpropylguanidine
- isomer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000002357 guanidines Chemical class 0.000 title 1
- 229940083094 guanine derivative acting on arteriolar smooth muscle Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 1
- 102000004257 Potassium Channel Human genes 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 108020001213 potassium channel Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30671489A | 1989-02-03 | 1989-02-03 | |
| US07/306,714 | 1989-02-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2009074A1 true CA2009074A1 (fr) | 1990-08-03 |
| CA2009074C CA2009074C (fr) | 1999-07-27 |
Family
ID=23186533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002009074A Expired - Fee Related CA2009074C (fr) | 1989-02-03 | 1990-02-01 | Ameliorations concernant les derives de guanidine |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0381504A3 (fr) |
| JP (1) | JP2823631B2 (fr) |
| KR (1) | KR100220989B1 (fr) |
| CN (1) | CN1043527C (fr) |
| AU (1) | AU623217B2 (fr) |
| CA (1) | CA2009074C (fr) |
| HU (1) | HU208959B (fr) |
| IE (1) | IE900391L (fr) |
| IL (1) | IL93252A0 (fr) |
| MX (1) | MX170706B (fr) |
| NZ (1) | NZ232336A (fr) |
| PT (1) | PT93033B (fr) |
| ZA (1) | ZA90772B (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ229828A (en) * | 1988-08-09 | 1992-03-26 | Squibb & Sons Inc | Aryl cyanoguanidine derivatives and pharmaceutical compositions |
| JPH05294935A (ja) * | 1991-03-15 | 1993-11-09 | Green Cross Corp:The | アミノピリジン系化合物 |
| US5371086A (en) * | 1991-03-15 | 1994-12-06 | The Green Cross Corporation | Aminopyridine compounds |
| AU4530693A (en) * | 1992-08-13 | 1994-03-15 | Upjohn Company, The | Cyanoguanidines as potassium channel blockers |
| GB9219472D0 (en) * | 1992-09-15 | 1992-10-28 | Leo Pharm Prod Ltd | Chemical compounds |
| JPH08511264A (ja) * | 1993-06-11 | 1996-11-26 | ジ・アップジョン・カンパニー | Ｋ−チャンネル遮断剤としてのピリミジン，シアノグアニジン |
| EP0956866A1 (fr) * | 1996-12-26 | 1999-11-17 | Kirin Beer Kabushiki Kaisha | Medicaments pour soigner les troubles de la circulation ophtalmiques |
| FR2760838B1 (fr) * | 1997-03-13 | 1999-05-21 | Corning Inc | Circuit fluidique integre d'execution d'un processus de preparation ou d'analyse d'un echantillon de matiere fluide, son procede de fabrication et appareil d'exploitation de ce circuit |
| US6645968B2 (en) | 1999-08-03 | 2003-11-11 | Abbott Laboratories | Potassium channel openers |
| MXPA02001207A (es) * | 1999-08-03 | 2002-07-30 | Abbott Lab | Abridores de canal de potasio. |
| CN105580233B (zh) * | 2013-09-27 | 2018-05-29 | 三菱电机株式会社 | 功率转换装置 |
| JP7437932B2 (ja) * | 2019-12-27 | 2024-02-26 | 三井化学株式会社 | 廃水処理方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1489879A (en) * | 1974-12-20 | 1977-10-26 | Leo Pharm Prod Ltd | N'-cyano-n'-3-pyridylguanidines |
| FR2624699B1 (fr) * | 1987-12-18 | 1990-04-13 | Bernard Lyon I Universite Clau | Derives heterocycliques de n-carbamoyl-, n-thiocarbamoyl- ou n-amidino-glycine ou beta-alanine utiles comme agents edulcorants |
-
1990
- 1990-02-01 KR KR1019900001152A patent/KR100220989B1/ko not_active Expired - Fee Related
- 1990-02-01 EP EP19900301073 patent/EP0381504A3/fr not_active Withdrawn
- 1990-02-01 PT PT93033A patent/PT93033B/pt not_active IP Right Cessation
- 1990-02-01 HU HU90641A patent/HU208959B/hu not_active IP Right Cessation
- 1990-02-01 ZA ZA90772A patent/ZA90772B/xx unknown
- 1990-02-01 NZ NZ232336A patent/NZ232336A/en unknown
- 1990-02-01 IL IL93252A patent/IL93252A0/xx not_active IP Right Cessation
- 1990-02-01 MX MX019348A patent/MX170706B/es unknown
- 1990-02-01 AU AU48977/90A patent/AU623217B2/en not_active Ceased
- 1990-02-01 CA CA002009074A patent/CA2009074C/fr not_active Expired - Fee Related
- 1990-02-02 CN CN90100487A patent/CN1043527C/zh not_active Expired - Fee Related
- 1990-02-02 IE IE900391A patent/IE900391L/xx unknown
- 1990-02-02 JP JP2025003A patent/JP2823631B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ZA90772B (en) | 1991-10-30 |
| PT93033B (pt) | 1996-03-29 |
| EP0381504A2 (fr) | 1990-08-08 |
| HUT53876A (en) | 1990-12-28 |
| HU900641D0 (en) | 1990-04-28 |
| KR100220989B1 (ko) | 1999-09-15 |
| CA2009074C (fr) | 1999-07-27 |
| AU623217B2 (en) | 1992-05-07 |
| AU4897790A (en) | 1990-08-09 |
| HU208959B (en) | 1994-02-28 |
| CN1043527C (zh) | 1999-06-02 |
| IE900391L (en) | 1990-08-03 |
| CN1044654A (zh) | 1990-08-15 |
| IL93252A0 (en) | 1990-11-29 |
| MX170706B (es) | 1993-09-08 |
| EP0381504A3 (fr) | 1991-09-04 |
| KR900012897A (ko) | 1990-09-03 |
| NZ232336A (en) | 1991-07-26 |
| JPH02235868A (ja) | 1990-09-18 |
| PT93033A (pt) | 1990-11-07 |
| JP2823631B2 (ja) | 1998-11-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |