CA2015671A1 - Derives de phosphonomethoxytetrahydrofuranyl-purine/pyrimidine - Google Patents

Derives de phosphonomethoxytetrahydrofuranyl-purine/pyrimidine

Info

Publication number: CA2015671A1
Authority: CA; Canada
Prior art keywords: purine; alkyl; hydrogen; different; same
Prior art date: 1989-05-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA2015671A

Other languages

English (en)

Other versions

CA2015671C (fr

Inventor

Choung U. Kim

John C. Martin

Bing Y. Luh

Peter F. Misco

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Stichting Rega VZW

Institute of Organic Chemistry and Biochemistry CAS

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-05-15

Filing date

1990-04-27

Publication date

1990-11-15

1990-04-27 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

1990-04-27 Priority to CA002297294A priority Critical patent/CA2297294C/fr

1990-11-15 Publication of CA2015671A1 publication Critical patent/CA2015671A1/fr

2000-04-25 Application granted granted Critical

2000-04-25 Publication of CA2015671C publication Critical patent/CA2015671C/fr

2010-04-27 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

BTRAURKQNWJCBW-UHFFFAOYSA-N [2-(oxolan-2-yl)-7H-purin-8-yl]oxymethylphosphonic acid Chemical class P(=O)(O)(O)COC1=NC2=NC(=NC=C2N1)C1OCCC1 BTRAURKQNWJCBW-UHFFFAOYSA-N 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 5
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000000561 purinyl group Chemical class N1=C(N=C2N=CNC2=C1)* 0.000 abstract 3
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
KDCGOANMDULRCW-UHFFFAOYSA-N Purine Natural products N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 abstract 2
CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical group C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 abstract 2
208000036142 Viral infection Diseases 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
230000000840 anti-viral effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
150000002118 epoxides Chemical class 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
230000009385 viral infection Effects 0.000 abstract 1

Landscapes

Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CA002015671A 1989-05-15 1990-04-27 Derives de phosphonomethoxytetrahydrofuranyl-purine/pyrimidine Expired - Lifetime CA2015671C (fr)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
CA002297294A CA2297294C (fr)	1989-05-15	1990-04-27	Derives de phosphonomethoxymethylpurine/pyrimidine

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US35230389A	1989-05-15	1989-05-15
US352,303		1989-05-15
US48165990A	1990-02-22	1990-02-22
US481,659		1990-02-22

Related Child Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002297294A Division CA2297294C (fr)	1989-05-15	1990-04-27	Derives de phosphonomethoxymethylpurine/pyrimidine

Publications (2)

Publication Number	Publication Date
CA2015671A1 true CA2015671A1 (fr)	1990-11-15
CA2015671C CA2015671C (fr)	2000-04-25

Family

ID=26997478

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002015671A Expired - Lifetime CA2015671C (fr)	1989-05-15	1990-04-27	Derives de phosphonomethoxytetrahydrofuranyl-purine/pyrimidine

Country Status (1)

Country	Link
CA (1)	CA2015671C (fr)

1990
- 1990-04-27 CA CA002015671A patent/CA2015671C/fr not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA2015671C (fr)	2000-04-25

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Legal Events

Date	Code	Title	Description
1990-07-19	EEER	Examination request
2010-04-27	MKEX	Expiry