CA2016551A1 - Derives de thieno-triazolo-diazepine, procede de preparation, et composes therapeutiques contenant lesdits derives - Google Patents

Derives de thieno-triazolo-diazepine, procede de preparation, et composes therapeutiques contenant lesdits derives

Info

Publication number
CA2016551A1
CA2016551A1 CA2016551A CA2016551A CA2016551A1 CA 2016551 A1 CA2016551 A1 CA 2016551A1 CA 2016551 A CA2016551 A CA 2016551A CA 2016551 A CA2016551 A CA 2016551A CA 2016551 A1 CA2016551 A1 CA 2016551A1
Authority
CA
Canada
Prior art keywords
thieno
triazolo
same
preparation process
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2016551A
Other languages
English (en)
Other versions
CA2016551C (fr
Inventor
Pierre Braquet
Andre Esanu
Jean-Pierre Laurent
Jacques Pommier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2016551A1 publication Critical patent/CA2016551A1/fr
Application granted granted Critical
Publication of CA2016551C publication Critical patent/CA2016551C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002016551A 1989-05-13 1990-05-11 Derives de thieno-triazolo-diazepine, procede de preparation, et composes therapeutiques contenant lesdits derives Expired - Fee Related CA2016551C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898911030A GB8911030D0 (en) 1989-05-13 1989-05-13 Hetrazepine derivatives
GB8911030.8 1989-05-13

Publications (2)

Publication Number Publication Date
CA2016551A1 true CA2016551A1 (fr) 1990-11-13
CA2016551C CA2016551C (fr) 1997-09-09

Family

ID=10656702

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002016551A Expired - Fee Related CA2016551C (fr) 1989-05-13 1990-05-11 Derives de thieno-triazolo-diazepine, procede de preparation, et composes therapeutiques contenant lesdits derives

Country Status (32)

Country Link
US (1) US5049559A (fr)
JP (1) JPH06104668B2 (fr)
KR (1) KR900018113A (fr)
AR (1) AR245725A1 (fr)
AT (1) AT399153B (fr)
AU (1) AU628171B2 (fr)
BE (1) BE1004122A3 (fr)
CA (1) CA2016551C (fr)
CH (1) CH681009A5 (fr)
DE (1) DE4015137C2 (fr)
DK (1) DK102990A (fr)
DZ (1) DZ1414A1 (fr)
ES (1) ES2019840A6 (fr)
FI (1) FI93119C (fr)
FR (2) FR2646774B1 (fr)
GB (2) GB8911030D0 (fr)
GR (1) GR1000295B (fr)
HK (1) HK94992A (fr)
IE (1) IE65246B1 (fr)
IN (1) IN174000B (fr)
IT (1) IT1240935B (fr)
LU (1) LU87733A1 (fr)
MA (1) MA21842A1 (fr)
NL (1) NL9001089A (fr)
NO (1) NO173607C (fr)
NZ (1) NZ233574A (fr)
OA (1) OA09209A (fr)
PT (1) PT94008B (fr)
SE (1) SE505407C2 (fr)
SG (1) SG91992G (fr)
TN (1) TNSN90061A1 (fr)
ZA (1) ZA903305B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5468740A (en) * 1988-10-31 1995-11-21 Eisai Co., Ltd. 1,4-diazepine derivative and its pharmaceutical use
US5221671A (en) * 1988-10-31 1993-06-22 Eisai Co., Ltd. Triazolo-1,4-diazepine derivatives and their use in pharmaceuticals
US5304553A (en) * 1988-10-31 1994-04-19 Eisai Co., Ltd. 1,4-diazepine derivative and its pharmaceutical use
FI95708C (fi) * 1988-10-31 1996-03-11 Eisai Co Ltd Analogiamenetelmä 1,4-diatsepiinijohdannaisen ja sen farmaseuttisesti sopivan suolan valmistamiseksi
US5382579A (en) * 1988-10-31 1995-01-17 Eisai Co., Ltd. Triazolo-1,4-diazepine derivatives and their use in pharmaceuticals
AT394563B (de) * 1990-05-09 1992-05-11 Scras Verfahren zur herstellung von thieno-triazolodiazepinderivaten
GB9207645D0 (en) * 1992-04-08 1992-05-27 Smithkline Beecham Corp Methods
ES2061406B1 (es) * 1993-05-07 1995-06-01 Uriach & Cia Sa J Nuevos derivados de la 2-(quinolina) con actividad farmacologica.
US6262044B1 (en) 1998-03-12 2001-07-17 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (PTPASES)
FR2779652B1 (fr) * 1998-06-15 2001-06-08 Sod Conseils Rech Applic Utilisation de diazepines pour la preparation de medicaments destines a traiter les etats pathologiques ou les maladies dans lesquels un des recepteurs de la somatostatine est implique
WO2001083440A2 (fr) * 2000-04-28 2001-11-08 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Synthese et utilisation de thienotriazolodiazepines
CN1812983A (zh) 2003-05-30 2006-08-02 兰贝克赛实验室有限公司 取代的吡咯衍生物及其作为hmg－co抑制剂的用途
SG166829A1 (en) 2005-11-08 2010-12-29 Ranbaxy Lab Ltd Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3435973A1 (de) * 1984-10-01 1986-04-10 Boehringer Ingelheim KG, 6507 Ingelheim Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
DE3724031A1 (de) * 1986-07-22 1988-01-28 Boehringer Ingelheim Kg Neue hetrazepine und verfahren zu ihrer herstellung
US5028603A (en) * 1987-06-08 1991-07-02 Yoshitomi Pharmaceutical Industries, Ltd. Ester-substituted thienotriazolodiazepine compounds and pharmaceutical uses thereof

Also Published As

Publication number Publication date
FI93119B (fi) 1994-11-15
BE1004122A3 (fr) 1992-09-29
SE9001670D0 (sv) 1990-05-09
NO901813D0 (no) 1990-04-24
FI93119C (fi) 1995-02-27
FR2646774B1 (fr) 1992-02-14
KR900018113A (ko) 1990-12-20
NO901813L (no) 1990-11-14
GB8911030D0 (en) 1989-06-28
FI902355A0 (fi) 1990-05-11
PT94008A (pt) 1991-01-08
AU5493190A (en) 1990-11-15
US5049559A (en) 1991-09-17
IE901583L (en) 1990-11-13
AR245725A1 (es) 1994-02-28
AU628171B2 (en) 1992-09-10
FR2646851B1 (fr) 1992-02-14
MA21842A1 (fr) 1990-12-31
NL9001089A (nl) 1990-12-03
IE65246B1 (en) 1995-10-04
DZ1414A1 (fr) 2004-09-13
ATA95690A (de) 1994-08-15
DE4015137A1 (de) 1990-11-15
FR2646774A1 (fr) 1990-11-16
DE4015137C2 (de) 2003-06-12
AT399153B (de) 1995-03-27
DK102990A (da) 1990-11-14
GB9010403D0 (en) 1990-06-27
PT94008B (pt) 1996-12-31
IT9020276A1 (it) 1991-11-11
IT1240935B (it) 1993-12-27
NO173607B (no) 1993-09-27
NO173607C (no) 1994-01-05
GR1000295B (el) 1992-05-12
OA09209A (fr) 1992-06-30
IT9020276A0 (it) 1990-05-11
NZ233574A (en) 1991-07-26
HK94992A (en) 1992-12-04
ES2019840A6 (es) 1991-07-01
CH681009A5 (en) 1992-12-31
SG91992G (en) 1992-12-04
TNSN90061A1 (fr) 1991-03-05
JPH06104668B2 (ja) 1994-12-21
ZA903305B (en) 1991-02-27
FR2646851A1 (fr) 1990-11-16
JPH035484A (ja) 1991-01-11
SE9001670L (fr)
IN174000B (fr) 1994-08-20
GR900100319A (en) 1991-10-10
CA2016551C (fr) 1997-09-09
GB2231330B (en) 1992-04-29
DK102990D0 (da) 1990-04-26
SE505407C2 (sv) 1997-08-25
LU87733A1 (fr) 1990-09-19
GB2231330A (en) 1990-11-14

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed