CA2017573A1 - Derives de 4-(hydroxydiphenylmethyl)-1-piperidylphenylalkane utilises comme antihistaminiques et methode de traitement d'une reaction allergique - Google Patents

Derives de 4-(hydroxydiphenylmethyl)-1-piperidylphenylalkane utilises comme antihistaminiques et methode de traitement d'une reaction allergique

Info

Publication number: CA2017573A1
Authority: CA; Canada
Prior art keywords: derivatives; hydroxydiphenylmethyl; antihistamines; treatment; allergic response
Prior art date: 1989-05-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA2017573A

Other languages

English (en)

Other versions

CA2017573C (fr

Inventor

Eckhardt Pein

Helmut Ritter

Reinhard Laven

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Schaper und Bruemmer GmbH and Co KG

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-05-26

Filing date

1990-05-25

Publication date

1990-11-26

1990-05-25 Application filed by Individual filed Critical Individual

1990-11-26 Publication of CA2017573A1 publication Critical patent/CA2017573A1/fr

1996-05-21 Application granted granted Critical

1996-05-21 Publication of CA2017573C publication Critical patent/CA2017573C/fr

2010-05-25 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

208000026935 allergic disease Diseases 0.000 title abstract 2
229940125715 antihistaminic agent Drugs 0.000 title abstract 2
239000000739 antihistaminic agent Substances 0.000 title abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical compound [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)

CA002017573A 1989-05-26 1990-05-25 Derives de 4-(hydroxydiphenylmethyl)-1-piperidylphenylalkane utilises comme antihistaminiques et methode de traitement d'une reaction allergique Expired - Fee Related CA2017573C (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DEP3917241.4		1989-05-26
DE3917241A DE3917241A1 (de)	1989-05-26	1989-05-26	4-(hydroxydiphenylmethyl)-1-piperidyl-phenylalkan-derivate

Publications (2)

Publication Number	Publication Date
CA2017573A1 true CA2017573A1 (fr)	1990-11-26
CA2017573C CA2017573C (fr)	1996-05-21

Family

ID=6381490

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002017573A Expired - Fee Related CA2017573C (fr)	1989-05-26	1990-05-25	Derives de 4-(hydroxydiphenylmethyl)-1-piperidylphenylalkane utilises comme antihistaminiques et methode de traitement d'une reaction allergique

Country Status (7)

Country	Link
US (1)	US5077301A (fr)
EP (1)	EP0399547B1 (fr)
JP (1)	JP2760633B2 (fr)
CA (1)	CA2017573C (fr)
DE (2)	DE3917241A1 (fr)
ES (1)	ES2036514T1 (fr)
HU (1)	HU00018A9 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1997022583A1 (fr) *	1995-12-20	1997-06-26	Eckhart Pein	Nouveaux derives de 1-phenylalkyl/alkylene-4-(.alpha.-hydroxydiphenylmethyl)-piperidine et leur utilisation comme antagonistes de la serotonine
USH1996H1 (en) *	1997-11-20	2001-10-02	Fmc Corporation	Insecticidal photostable acid salt derivatives of N-benzyl-4-benzhydrolpiperidines

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3014037A (en) *	1957-09-12	1961-12-19	Searle & Co	N-alkoxyphenalkyl-alpha, alpha-diphenyl-4-piperidinemethanols and processes
US3068237A (en) *	1961-03-17	1962-12-11	Searle & Co	N-[(chloro/nitro/amino)phenylalkyl]-alpha, alpha-diphenylpipidinemethanols
ZA728544B (en) *	1972-01-28	1974-02-27	Richardson Merrell Inc	Alpha-aryl-4-substituted piperidinoalkanol derivatives
US3806526A (en) *	1972-01-28	1974-04-23	Richardson Merrell Inc	1-aroylalkyl-4-diphenylmethyl piperidines
BE794596A (fr) *	1972-01-28	1973-05-16	Richardson Merrell Inc	Piperidinoalcanone-oximes substituees et leur procede de preparation
US3941795A (en) *	1974-02-08	1976-03-02	Richardson-Merrell Inc.	α-ARYL-4-SUBSTITUTED PIPERIDINOALKANOL DERIVATIVES
US3946022A (en) *	1974-03-04	1976-03-23	Richardson-Merrell Inc.	Piperidine derivatives
US4254130A (en) *	1979-04-10	1981-03-03	Richardson-Merrell Inc.	Piperidine derivatives
US4254129A (en) *	1979-04-10	1981-03-03	Richardson-Merrell Inc.	Piperidine derivatives

1989
- 1989-05-26 DE DE3917241A patent/DE3917241A1/de active Granted
1990
- 1990-05-25 ES ES199090109955T patent/ES2036514T1/es active Pending
- 1990-05-25 JP JP2136922A patent/JP2760633B2/ja not_active Expired - Lifetime
- 1990-05-25 US US07/528,966 patent/US5077301A/en not_active Expired - Fee Related
- 1990-05-25 DE DE9090109955T patent/DE59002266D1/de not_active Expired - Fee Related
- 1990-05-25 EP EP90109955A patent/EP0399547B1/fr not_active Expired - Lifetime
- 1990-05-25 CA CA002017573A patent/CA2017573C/fr not_active Expired - Fee Related
1994
- 1994-08-16 HU HU94P/P00018P patent/HU00018A9/hu unknown

Also Published As

Publication number	Publication date
ES2036514T1 (es)	1993-06-01
EP0399547A2 (fr)	1990-11-28
JPH03115221A (ja)	1991-05-16
JP2760633B2 (ja)	1998-06-04
DE3917241A1 (de)	1990-11-29
EP0399547A3 (fr)	1992-01-22
EP0399547B1 (fr)	1993-08-11
HU00018A9 (en)	1995-01-30
DE3917241C2 (fr)	1991-12-12
CA2017573C (fr)	1996-05-21
US5077301A (en)	1991-12-31
DE59002266D1 (de)	1993-09-16

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Legal Events

Date	Code	Title	Description
1992-03-02	EEER	Examination request
2003-05-26	MKLA	Lapsed