CA2021178C - Preparation d'anhydride n-formyl-l-aspartique - Google Patents

Preparation d'anhydride n-formyl-l-aspartique

Info

Publication number
CA2021178C
CA2021178C CA002021178A CA2021178A CA2021178C CA 2021178 C CA2021178 C CA 2021178C CA 002021178 A CA002021178 A CA 002021178A CA 2021178 A CA2021178 A CA 2021178A CA 2021178 C CA2021178 C CA 2021178C
Authority
CA
Canada
Prior art keywords
added
aspartic
acetic anhydride
anhydride
aspartic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002021178A
Other languages
English (en)
Other versions
CA2021178A1 (fr
Inventor
John B. Hill
Hugh L. Dryden, Jr.
Robert Erickson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nutrasweet Co
Original Assignee
Nutrasweet Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nutrasweet Co filed Critical Nutrasweet Co
Priority to CA002021178A priority Critical patent/CA2021178C/fr
Publication of CA2021178A1 publication Critical patent/CA2021178A1/fr
Application granted granted Critical
Publication of CA2021178C publication Critical patent/CA2021178C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

De l'anhydride N-formyl-L-aspartique est préparé à l'aide d'un excès minimum d'acide formique. L'anhydride acétique et un alcool secondaire en C3-C6 sont ajoutés au mélange réactionnel pour consommer l'excès d'acide formique. Le mélange réactionnel obtenu peut être utilisé tel quel dans d'autres réactions.
CA002021178A 1990-07-13 1990-07-13 Preparation d'anhydride n-formyl-l-aspartique Expired - Fee Related CA2021178C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002021178A CA2021178C (fr) 1990-07-13 1990-07-13 Preparation d'anhydride n-formyl-l-aspartique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002021178A CA2021178C (fr) 1990-07-13 1990-07-13 Preparation d'anhydride n-formyl-l-aspartique

Publications (2)

Publication Number Publication Date
CA2021178A1 CA2021178A1 (fr) 1992-01-14
CA2021178C true CA2021178C (fr) 1998-04-28

Family

ID=4145476

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002021178A Expired - Fee Related CA2021178C (fr) 1990-07-13 1990-07-13 Preparation d'anhydride n-formyl-l-aspartique

Country Status (1)

Country Link
CA (1) CA2021178C (fr)

Also Published As

Publication number Publication date
CA2021178A1 (fr) 1992-01-14

Similar Documents

Publication Publication Date Title
CA2021178C (fr) Preparation d'anhydride n-formyl-l-aspartique
AU649623B2 (en) Process for the preparation of N-formyl-L-aspartic anhydride
Wheeler et al. Synthesis of 1-aminocyclopropenecarboxylic acid: the unsaturated analog of ACC
US4801742A (en) N-formylation of amino carboxylates with alkyl formates
JP2609368B2 (ja) 単離したN―ホルミル―L―アスパラギン酸無水物を使用するα―L―アスパルチル―L―フェニルアラニンメチルエステル塩酸塩の製造方法
CA1268598A (fr) METHODE DE PREPARATION D'ESTER METHYLIQUE DE .alpha.-L-ASPARTYL-L-PHENYLALANINE ET DE SON CHLORHYDRATE
US4945172A (en) Preparation of N-formyl-L-aspartic anhydride
EP0307496B1 (fr) Procédé pour la production de la N-Formyl-aspartyl-phénylalanine et de son ester méthylique
JPH0680075B2 (ja) N―ホルミル―α―L―アスパルチル―L―フェニルアラニンメチルエステルの製造法
US4673744A (en) Method for conversion of β-aspartylphenylalanine derivatives to .alpha.
CA1244008A (fr) Synthese de l'aspartame
CZ282717B6 (cs) Způsob přípravy anhydridu N-formyl-L-asparagové kyseliny
US4789757A (en) N-formylation of amino carboxylic compounds with formamide
Nomura et al. Triphenylstibine oxide–phosphorus (V) sulfide as a novel condensation catalyst system: application to the synthesis of dipeptides
RO109449B1 (ro) Procedeu pentru prepararea anhidridei N-formil-L-aspartice
PL163892B1 (pl) Sposób wytwarzania bezwodnika kwasu N-formylo-L-asparaginowego
US4440950A (en) Process for preparation of aminobenzaldehydes and aminobenzylketones
CA1318459C (fr) Imides, procede pour leur production et procede pour la production de dipeptides
US5017690A (en) Deblocking N-formyl aspartame compounds
HRP921062A2 (en) Process for the preparation of calcium 2,5-dihydroxy-benzensulfonate
AU648291B2 (en) A one-pot process for the preparation of alpha-L-aspartyl-L-phenylalanine methyl ester hydrochloride
JP2598470B2 (ja) N−ベンジルオキシカルボニル―αーL―アスパルチル―L―フェニルアラニンメチルエステルの製造方法
JPH03153653A (ja) N―(1―アルコキシカルボニルスチリル)フマルアミド酸およびその製造方法
KR860001047B1 (ko) 아스팔틸-페닐알라닌 메틸에스테르의 제조방법
JP2647420B2 (ja) N−保護−α−L−アスパルチル−L−フェニルアラニンメチルエステルの製造方法

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed
MKLA Lapsed

Effective date: 20020715