CA2030237A1 - Methode de traitement de l'alcoolisme par inhibition du besoin de boire par administration percutanee d'un antagoniste des opiaces et dispositif permettant l'administration dudit antagoniste - Google Patents
Methode de traitement de l'alcoolisme par inhibition du besoin de boire par administration percutanee d'un antagoniste des opiaces et dispositif permettant l'administration dudit antagonisteInfo
- Publication number
- CA2030237A1 CA2030237A1 CA2030237A CA2030237A CA2030237A1 CA 2030237 A1 CA2030237 A1 CA 2030237A1 CA 2030237 A CA2030237 A CA 2030237A CA 2030237 A CA2030237 A CA 2030237A CA 2030237 A1 CA2030237 A1 CA 2030237A1
- Authority
- CA
- Canada
- Prior art keywords
- extinguishing
- alcohol
- opiate antagonist
- transdermally administered
- treating alcoholism
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US439,050 | 1989-11-20 | ||
| US07/439,050 US5096715A (en) | 1989-11-20 | 1989-11-20 | Method and means for treating alcoholism by extinguishing the alcohol-drinking response using a transdermally administered opiate antagonist |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2030237A1 true CA2030237A1 (fr) | 1991-05-21 |
| CA2030237C CA2030237C (fr) | 1997-12-30 |
Family
ID=23743078
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002030237A Expired - Lifetime CA2030237C (fr) | 1989-11-20 | 1990-11-19 | Methode de traitement de l'alcoolisme par inhibition du besoin de boire par administration percutanee d'un antagoniste des opiaces et dispositif permettant l'administration dudit antagoniste |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5096715A (fr) |
| EP (1) | EP0429039B1 (fr) |
| AT (1) | ATE119393T1 (fr) |
| AU (1) | AU639042B2 (fr) |
| CA (1) | CA2030237C (fr) |
| DE (1) | DE69017596T2 (fr) |
| DK (1) | DK0429039T3 (fr) |
| ES (1) | ES2074513T3 (fr) |
| FI (1) | FI905718L (fr) |
| NZ (2) | NZ247173A (fr) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5086058A (en) * | 1990-06-04 | 1992-02-04 | Alko Ltd. | Method for treating alcoholism with nalmefene |
| DE4223004A1 (de) * | 1992-07-13 | 1994-01-20 | Liedtke Pharmed Gmbh | Einzeldosierte halbfeste topische Arzneiform zur Transdermaltherapie |
| US6096756A (en) * | 1992-09-21 | 2000-08-01 | Albert Einstein College Of Medicine Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists |
| US5580876A (en) * | 1992-09-21 | 1996-12-03 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists |
| USRE36547E (en) * | 1992-09-21 | 2000-02-01 | Albert Einstein College Of Medicine Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by exogenous and endogenous opioid agonists |
| US5580574A (en) * | 1994-04-28 | 1996-12-03 | Hoffmann-La Roche Inc. | Pharmaceutical composition for transdermal delivery |
| US5552153A (en) * | 1994-04-28 | 1996-09-03 | Hoffman-La Roche Inc. | Pharmaceutical composition for transdermal delivery |
| DE4423850A1 (de) * | 1994-07-07 | 1996-01-11 | Labtec Gmbh | Transdermales therapeutisches System zur Applikation von Naloxon |
| US5587381A (en) * | 1995-03-27 | 1996-12-24 | Sinclair; John D. | Method for terminating methadone maintenance through extinction of the opiate-taking responses |
| US6375957B1 (en) | 1997-12-22 | 2002-04-23 | Euro-Celtique, S.A. | Opioid agonist/opioid antagonist/acetaminophen combinations |
| EP1041987B1 (fr) | 1997-12-22 | 2006-04-19 | Euro-Celtique S.A. | Formulation pharmaceutique pour administration orale comprenant en combinaison un agoniste des récepteurs opiacés et la naltrexone |
| EP1041988A4 (fr) | 1997-12-22 | 2002-03-13 | Euro Celtique Sa | Procede prevenant l'abus des doses orales d'opioides |
| ATE399565T1 (de) | 1998-07-07 | 2008-07-15 | Transdermal Technologies Inc | Zusammensetzungen für die schnelle und nicht- irritierende transdermale verabreichung von pharmazeutika and verfahren zur formuliering davon und ihren verabreichung |
| WO2001040269A2 (fr) * | 1999-11-30 | 2001-06-07 | Corixa Corporation | Compositions et methodes destinees au traitement et au diagnostic du cancer du sein |
| US6716449B2 (en) | 2000-02-08 | 2004-04-06 | Euro-Celtique S.A. | Controlled-release compositions containing opioid agonist and antagonist |
| EP2092936B1 (fr) | 2000-02-08 | 2013-03-20 | Euro-Celtique S.A. | Compositions orales inviolables comprenant des agonistes opioïdes |
| US20040024004A1 (en) * | 2001-05-04 | 2004-02-05 | Sherman Barry M. | Novel compositions and methods for enhancing potency or reducing adverse side effects of opioid agonists |
| US20060121103A1 (en) * | 2000-05-11 | 2006-06-08 | Kenneth Kirby | Transdermal delivery system |
| US6569449B1 (en) | 2000-11-13 | 2003-05-27 | University Of Kentucky Research Foundation | Transdermal delivery of opioid antagonist prodrugs |
| EP1387673B1 (fr) | 2001-05-11 | 2010-12-29 | Endo Pharmaceuticals Inc. | Forme posologique d'opioides a liberation prolongee empechant la consommation abusive |
| US7879211B2 (en) * | 2001-07-13 | 2011-02-01 | Arkray, Inc. | Analyzing instrument, lancet-integrated attachment for concentration measuring device provided with analyzing instrument, and body fluid sampling tool |
| SI1416842T1 (sl) * | 2001-07-18 | 2009-06-30 | Euro Celtique Sa | Farmacevtske kombinacije oksikodona in naloksona |
| IL160222A0 (en) | 2001-08-06 | 2004-07-25 | Euro Celtique Sa | Opioid agonist formulations with releasable and sequestered antagonist |
| US20030044458A1 (en) * | 2001-08-06 | 2003-03-06 | Curtis Wright | Oral dosage form comprising a therapeutic agent and an adverse-effect agent |
| US20030157168A1 (en) * | 2001-08-06 | 2003-08-21 | Christopher Breder | Sequestered antagonist formulations |
| RU2004107501A (ru) * | 2001-08-14 | 2005-02-20 | Байотай Терапис Корпорейшн (Fi) | Способ лечения алкоголизма или злоупотребления алкоголем |
| US20040033253A1 (en) * | 2002-02-19 | 2004-02-19 | Ihor Shevchuk | Acyl opioid antagonists |
| HUE032656T2 (en) | 2002-04-05 | 2017-10-30 | Euro Celtique Sa | Pharmaceutical composition containing oxicodone and naloxone |
| CN1703200B (zh) * | 2002-09-20 | 2012-02-29 | 奥尔制药公司 | 隔离亚单元和相关组合物及方法 |
| US20040202717A1 (en) | 2003-04-08 | 2004-10-14 | Mehta Atul M. | Abuse-resistant oral dosage forms and method of use thereof |
| AU2004229551A1 (en) * | 2003-04-14 | 2004-10-28 | Pain Therapeutics, Inc. | Methods for the treatment of pain comprising opioid antagonists |
| MY135852A (en) | 2003-04-21 | 2008-07-31 | Euro Celtique Sa | Pharmaceutical products |
| US20060009478A1 (en) * | 2003-10-15 | 2006-01-12 | Nadav Friedmann | Methods for the treatment of back pain |
| EP1604666A1 (fr) * | 2004-06-08 | 2005-12-14 | Euro-Celtique S.A. | Opioides pour le traitement de la bronchopneumopathie chronique obstructive |
| US20080045610A1 (en) * | 2004-09-23 | 2008-02-21 | Alexander Michalow | Methods for regulating neurotransmitter systems by inducing counteradaptations |
| CA2580694A1 (fr) * | 2004-09-23 | 2006-03-30 | Alexander Michalow | Methodes permettant de reguler les systemes de neurotransmetteurs en induisant des contre-adaptations |
| US7910599B2 (en) | 2005-01-10 | 2011-03-22 | John David Sinclair | Method for treating eating disorders by selective extinction with transdermal naloxone |
| EP1702558A1 (fr) * | 2005-02-28 | 2006-09-20 | Euro-Celtique S.A. | Procédé et dispositif pour évaluer la fonction de l'activité intestinale |
| US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
| SI2719378T1 (sl) * | 2006-06-19 | 2016-11-30 | Alpharma Pharmaceuticals Llc | Farmacevtski sestavki |
| EP2152315B1 (fr) | 2007-05-25 | 2016-01-06 | Indivior UK Limited | Formulations d'administration prolongée de composés de rispéridone |
| US20100151014A1 (en) * | 2008-12-16 | 2010-06-17 | Alpharma Pharmaceuticals, Llc | Pharmaceutical composition |
| AU2008346870A1 (en) * | 2007-12-17 | 2009-07-16 | Alpharma Pharmaceuticals, Llc | Pharmaceutical composition |
| US8623418B2 (en) * | 2007-12-17 | 2014-01-07 | Alpharma Pharmaceuticals Llc | Pharmaceutical composition |
| EP2259780A2 (fr) | 2008-02-28 | 2010-12-15 | Syntropharma Limited | Composition pharmaceutique comprenant de la naltrexone |
| EP2317991B1 (fr) * | 2008-07-07 | 2017-05-03 | Euro-Celtique S.A. | Utilisation d'antagonistes opioïdes pour le traitement d'une rétention urinaire |
| SG174286A1 (en) | 2009-03-10 | 2011-10-28 | Euro Celtique Sa | Immediate release pharmaceutical compositions comprising oxycodone and naloxone |
| WO2011064769A1 (fr) | 2009-11-24 | 2011-06-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Procédés et compositions pharmaceutiques pour le traitement des bouffées de chaleur |
| GB2481017B (en) | 2010-06-08 | 2015-01-07 | Rb Pharmaceuticals Ltd | Microparticle buprenorphine suspension |
| US9272044B2 (en) | 2010-06-08 | 2016-03-01 | Indivior Uk Limited | Injectable flowable composition buprenorphine |
| US8939943B2 (en) | 2011-01-26 | 2015-01-27 | Kaleo, Inc. | Medicament delivery device for administration of opioid antagonists including formulations for naloxone |
| US8627816B2 (en) | 2011-02-28 | 2014-01-14 | Intelliject, Inc. | Medicament delivery device for administration of opioid antagonists including formulations for naloxone |
| JP2016525138A (ja) | 2013-07-23 | 2016-08-22 | ユーロ−セルティーク エス.エイ. | 疼痛および腸内ディスバイオシスをもたらす疾患および/または腸内細菌移行に対するリスクを高める疾患に罹患している患者における痛みの治療への使用のためのオキシコドンおよびナロキソンの組み合わせ |
| GB201404139D0 (en) | 2014-03-10 | 2014-04-23 | Rb Pharmaceuticals Ltd | Sustained release buprenorphine solution formulations |
| US11607026B2 (en) * | 2014-05-30 | 2023-03-21 | Johnson & Johnson Consumer Inc. | Device for delivery of skin care composition |
| US9517307B2 (en) | 2014-07-18 | 2016-12-13 | Kaleo, Inc. | Devices and methods for delivering opioid antagonists including formulations for naloxone |
| CN111447927A (zh) * | 2017-12-08 | 2020-07-24 | 帝国制药美国公司 | 纳洛酮经皮给药装置及其使用方法 |
| US12364692B2 (en) | 2020-02-14 | 2025-07-22 | Teikoku Pharma Usa, Inc. | Topical naloxone compositions and methods for using the same |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2837881A (en) * | 1952-12-13 | 1958-06-10 | Lawrence A Schneider | Encapsulated product and method and apparatus for making same |
| US3249109A (en) * | 1963-11-01 | 1966-05-03 | Maeth Harry | Topical dressing |
| US4351337A (en) * | 1973-05-17 | 1982-09-28 | Arthur D. Little, Inc. | Biodegradable, implantable drug delivery device, and process for preparing and using the same |
| IE49783B1 (en) * | 1979-05-18 | 1985-12-11 | Efamol Ltd | Pharmaceutical and dietary composition comprising epsilon-linolenic acids |
| US4629539A (en) * | 1982-07-08 | 1986-12-16 | Tdk Corporation | Metal layer patterning method |
| AU8952282A (en) * | 1982-08-25 | 1984-03-29 | Joel E. Bernstein | Method of treating pruritis and composition therefor |
| US4626539A (en) * | 1984-08-10 | 1986-12-02 | E. I. Dupont De Nemours And Company | Trandermal delivery of opioids |
| US4573995A (en) * | 1984-10-09 | 1986-03-04 | Alza Corporation | Transdermal therapeutic systems for the administration of naloxone, naltrexone and nalbuphine |
| US4818540A (en) * | 1985-02-25 | 1989-04-04 | Rutgers, The State University Of New Jersey | Transdermal fertility control system and process |
| US4806341A (en) * | 1985-02-25 | 1989-02-21 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit for narcotic analgesics and antagonists and process for administration |
| US4680172A (en) * | 1985-03-05 | 1987-07-14 | Ciba-Geigy Corporation | Devices and methods for treating memory impairment |
| US4645502A (en) * | 1985-05-03 | 1987-02-24 | Alza Corporation | Transdermal delivery of highly ionized fat insoluble drugs |
| DE3545926A1 (de) * | 1985-12-23 | 1987-07-02 | Allan Gerhard Fruehauf | Tuch oder dgl. mit darin integrierten, einen wirkstoff enthaltenden kapseln |
| ES2042527T3 (es) * | 1986-11-14 | 1993-12-16 | Theratech Inc | Un metodo para preparar una composicion farmaceutica aumentadora de la penetracion para la aplicacion topica. |
| EP0282156B1 (fr) * | 1987-03-09 | 1991-04-17 | Alza Corporation | Composition pour la prévention d'une allergie de contact par co-administration d'un corticostéroide avec un médicament sensibilisant |
| US4882335A (en) * | 1988-06-13 | 1989-11-21 | Alko Limited | Method for treating alcohol-drinking response |
-
1989
- 1989-11-20 US US07/439,050 patent/US5096715A/en not_active Expired - Lifetime
-
1990
- 1990-11-14 AU AU66650/90A patent/AU639042B2/en not_active Expired
- 1990-11-16 NZ NZ247173A patent/NZ247173A/en unknown
- 1990-11-16 NZ NZ236104A patent/NZ236104A/xx unknown
- 1990-11-19 EP EP90122076A patent/EP0429039B1/fr not_active Expired - Lifetime
- 1990-11-19 AT AT90122076T patent/ATE119393T1/de not_active IP Right Cessation
- 1990-11-19 CA CA002030237A patent/CA2030237C/fr not_active Expired - Lifetime
- 1990-11-19 DK DK90122076.4T patent/DK0429039T3/da active
- 1990-11-19 DE DE69017596T patent/DE69017596T2/de not_active Expired - Lifetime
- 1990-11-19 ES ES90122076T patent/ES2074513T3/es not_active Expired - Lifetime
- 1990-11-20 FI FI905718A patent/FI905718L/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DK0429039T3 (da) | 1995-03-27 |
| US5096715A (en) | 1992-03-17 |
| AU639042B2 (en) | 1993-07-15 |
| EP0429039B1 (fr) | 1995-03-08 |
| AU6665090A (en) | 1991-05-23 |
| CA2030237C (fr) | 1997-12-30 |
| DE69017596T2 (de) | 1995-07-06 |
| ES2074513T3 (es) | 1995-09-16 |
| FI905718A7 (fi) | 1991-05-21 |
| FI905718L (fi) | 1991-05-21 |
| DE69017596D1 (de) | 1995-04-13 |
| EP0429039A2 (fr) | 1991-05-29 |
| ATE119393T1 (de) | 1995-03-15 |
| NZ247173A (en) | 1997-07-27 |
| EP0429039A3 (en) | 1991-10-16 |
| NZ236104A (en) | 1993-04-28 |
| FI905718A0 (fi) | 1990-11-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |