CA2039021C - Dna sequence comprising a structural gene coding for xylose reductase and/or xylitol dehydrogenase - Google Patents

Dna sequence comprising a structural gene coding for xylose reductase and/or xylitol dehydrogenase Download PDF

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Publication number
CA2039021C
CA2039021C CA002039021A CA2039021A CA2039021C CA 2039021 C CA2039021 C CA 2039021C CA 002039021 A CA002039021 A CA 002039021A CA 2039021 A CA2039021 A CA 2039021A CA 2039021 C CA2039021 C CA 2039021C
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CA
Canada
Prior art keywords
microorganism
dna sequence
dna
xylose
xylitol dehydrogenase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002039021A
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English (en)
French (fr)
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CA2039021A1 (en
Inventor
Alexander W.M. Strasser
Michael Von Ciriacy-Wantrup
Cornelis P. Hollenberg
Peter Kotter
Rene Amore
Michael Piontek
Jutta Hagedorn
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Artes Biotechnology GmbH
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Artes Biotechnology GmbH
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Publication date
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Publication of CA2039021A1 publication Critical patent/CA2039021A1/en
Application granted granted Critical
Publication of CA2039021C publication Critical patent/CA2039021C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
CA002039021A 1990-03-26 1991-03-25 Dna sequence comprising a structural gene coding for xylose reductase and/or xylitol dehydrogenase Expired - Lifetime CA2039021C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4009676A DE4009676A1 (de) 1990-03-26 1990-03-26 Dna-sequenz, umfassend ein fuer xylosereduktase und/oder xylitoldehydrogenase codierendes strukturgen
DEP4009676.9 1990-03-26

Publications (2)

Publication Number Publication Date
CA2039021A1 CA2039021A1 (en) 1991-09-27
CA2039021C true CA2039021C (en) 2006-09-12

Family

ID=6403083

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002039021A Expired - Lifetime CA2039021C (en) 1990-03-26 1991-03-25 Dna sequence comprising a structural gene coding for xylose reductase and/or xylitol dehydrogenase

Country Status (8)

Country Link
EP (1) EP0450430B1 (2)
JP (3) JP3122153B2 (2)
AT (1) ATE154829T1 (2)
CA (1) CA2039021C (2)
DE (2) DE4009676A1 (2)
DK (1) DK0450430T3 (2)
ES (1) ES2104626T3 (2)
GR (1) GR3024409T3 (2)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
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US5866382A (en) * 1990-04-06 1999-02-02 Xyrofin Oy Xylose utilization by recombinant yeasts
FI901771A7 (fi) * 1990-04-06 1991-10-07 Valtion Teknillinen Anvaendning av xylos hos hybridjaest.
FI913197A0 (fi) * 1991-07-01 1991-07-01 Xyrofin Oy Nya jaeststammar med reducerad foermaoga att metabolisera xylitol, foerfarande foer bildande av dessa och deras anvaendning vid framstaellning av xylitol.
KR950704503A (ko) * 1992-11-05 1995-11-20 필립 프랑켄호이저, 주하 쿠르키넨 크실리톨을 제조하기 위한 재조합 방법 및 숙주(Recombinant method and host for manufacture of xylitol)
US7226761B2 (en) 1992-11-05 2007-06-05 Danisco Sweeteners Oy Manufacture of five-carbon sugars and sugar alcohols
US6723540B1 (en) 1992-11-05 2004-04-20 Xyrofin Oy Manufacture of xylitol using recombinant microbial hosts
EP0672161B1 (en) * 1992-11-05 1999-09-22 Xyrofin Oy Recombinant method and host for manufacture of xylitol
JP3574682B2 (ja) * 1993-09-24 2004-10-06 ダイセル化学工業株式会社 新規な酵素、該酵素を製造する方法、該酵素をコードするｄｎａ、該ｄｎａを含む形質転換体、該酵素による光学活性アルコール等の製造方法
US5712114A (en) * 1995-06-06 1998-01-27 Basf Aktiengesellschaft Compositions for expression of proteins in host cells using a preprocollagen signal sequence
IN191596B (2) 1996-05-06 2003-12-06 Purdue Research Foundation
DE69928656D1 (de) * 1998-04-20 2006-01-05 Forskarpatent I Syd Ab Lund Gentechnisch hergestellte hefestämme und deren mutanten zur fermentierung von lignocellulosehydrolysate
JP2000295994A (ja) * 1999-02-09 2000-10-24 Ajinomoto Co Inc キシリトールの製造法
FI20010308A0 (fi) * 2001-02-16 2001-02-16 Valtion Teknillinen Sienen käsitteleminen geneettisesti siten, että se pystyy käyttämään L-arabinoosia
US7309602B2 (en) 2006-04-13 2007-12-18 Ambrozea, Inc. Compositions and methods for producing fermentation products and residuals
BRPI0709946A2 (pt) * 2006-04-13 2011-08-02 Ambrozea Inc composições e métodos para produzir produtos e resìduos de fermentação
ES2797383T3 (es) * 2006-08-01 2020-12-02 Vwp Waste Proc Limited Reciclaje de residuos domésticos
BRPI0807237A2 (pt) 2007-02-02 2014-04-29 Kirin Holdings Kk Dna que codifica xilitol desidrogenase, construção de ácido nucléico, vetores, microorganismos e métodos para produzir xilitol desigrogenase e etanol
WO2008144012A2 (en) * 2007-05-14 2008-11-27 The Regents Of The University Of California Xylose- and arabinose- metabolizing enzyme -encoding nucleotide sequences with refined translational kinetics and methods of making same
US8940510B2 (en) 2007-11-16 2015-01-27 University Of Iowa Research Foundation Spray dried microbes and methods of preparation and use
JP5219074B2 (ja) * 2008-01-24 2013-06-26 独立行政法人産業技術総合研究所 キシロース発酵能が優れた六炭糖・五炭糖同時発酵酵母およびそれを用いたエタノールの高効率生産方法
JPWO2010095750A1 (ja) * 2009-02-23 2012-08-30 キリンホールディングス株式会社 キシロースを炭素源として使用しうる、キャンディダ・ユティリスによる物質の製造法
WO2011079388A1 (en) 2009-12-30 2011-07-07 Iogen Energy Corporation Modified yeast strains exhibiting enhanced fermentation of lignocellulosic hydrolysates
WO2011099657A1 (ko) * 2010-02-10 2011-08-18 건국대학교 산학협력단 신규 자일리톨 탈수소화효소 및 이를 이용한 ｌ-자일룰로즈의 생산방법
ES2623288T3 (es) 2010-08-20 2017-07-10 Codexis, Inc. Uso de proteínas de la familia de glicólido hidrolasa 61 en el procesamiento de celulosa
JP5881300B2 (ja) * 2011-03-04 2016-03-09 サントリーホールディングス株式会社 リグノセルロース系バイオマスからのエタノール醗酵微生物
DK2748317T3 (en) 2011-08-22 2017-07-17 Codexis Inc GH61 glycoside hydrolase protein variants and cofactors that enhance GH61 activity
US10619173B2 (en) 2014-07-22 2020-04-14 Iogen Corporation Process for using biogenic carbon dioxide derived from non-fossil organic material
CA2953162C (en) 2014-07-22 2023-01-31 Iogen Corporation Process for using biogenic carbon dioxide derived from non-fossil organic material
US11434509B2 (en) 2014-12-08 2022-09-06 Iogen Corporation Process for using biogenic carbon dioxide derived from non-fossil organic material
WO2017049394A1 (en) 2015-09-24 2017-03-30 Iogen Corporation Wet oxidation of biomass
CA3002682C (en) 2015-11-25 2022-06-21 Iogen Energy Corporation System and method for cooling pretreated biomass
US10662455B2 (en) 2015-12-18 2020-05-26 Iogen Corporation Sulfur dioxide and/or sulfurous acid pretreatment
WO2017136915A1 (en) 2016-02-10 2017-08-17 Iogen Corporation Pretreatment of lignocellulosic biomass with sulfur dioxide and/or sulfurous acid
CA3047841A1 (en) 2016-12-21 2018-06-28 Creatus Biosciences Inc. Xylitol producing metschnikowia species
CA3078833A1 (en) 2017-11-09 2019-05-16 Iogen Corporation Low temperature pretreatment with sulfur dioxide
CA3078822A1 (en) 2017-11-09 2019-05-16 Iogen Corporation Low temperature sulfur dioxide pretreatment
US11312977B2 (en) 2018-04-06 2022-04-26 Iogen Corporation Pretreatment with lignosulfonic acid

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2151635B (en) * 1983-12-08 1988-01-13 Ici Plc Production of single cell protein and sucrose
US4840903A (en) * 1985-08-08 1989-06-20 The United States Of America As Represented By The United States Department Of Energy Process for producing ethanol from plant biomass using the fungus paecilomyces sp.
DK122686D0 (da) * 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner

Also Published As

Publication number Publication date
JP2000139486A (ja) 2000-05-23
GR3024409T3 (en) 1997-11-28
DE4009676C2 (2) 1993-09-09
ATE154829T1 (de) 1997-07-15
DE69126632T2 (de) 1997-10-23
JPH06339383A (ja) 1994-12-13
JP2001103988A (ja) 2001-04-17
JP3122153B2 (ja) 2001-01-09
CA2039021A1 (en) 1991-09-27
JP3193917B2 (ja) 2001-07-30
DE69126632D1 (de) 1997-07-31
DK0450430T3 (da) 1998-01-19
ES2104626T3 (es) 1997-10-16
EP0450430A2 (en) 1991-10-09
EP0450430A3 (en) 1992-01-02
EP0450430B1 (en) 1997-06-25
DE4009676A1 (de) 1991-10-02

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