CA2040077A1 - Minigenes d'app recombinant pour l'expression de souris transgeniques comme modeles de la maladie d'alzheimer - Google Patents

Minigenes d'app recombinant pour l'expression de souris transgeniques comme modeles de la maladie d'alzheimer

Info

Publication number: CA2040077A1
Authority: CA; Canada
Prior art keywords: app; pmti; gene; expression; fragment
Prior art date: 1990-04-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA 2040077

Other languages

English (en)

Inventor

Dana O. Wirak

Richard Bayney

Triprayar V. Ramabhadran

Axel Unterbeck

Peter Rae

George Scangos

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bayer Corp

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-04-10

Filing date

1991-04-09

Publication date

1991-10-11

1991-04-09 Application filed by Individual filed Critical Individual

1991-10-11 Publication of CA2040077A1 publication Critical patent/CA2040077A1/fr

Status Abandoned legal-status Critical Current

Links

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Micro-Organisms Or Cultivation Processes Thereof (AREA)

CA 2040077 1990-04-10 1991-04-09 Minigenes d'app recombinant pour l'expression de souris transgeniques comme modeles de la maladie d'alzheimer Abandoned CA2040077A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US50770590A	1990-04-10	1990-04-10
US507,705		1990-04-10

Publications (1)

Publication Number	Publication Date
CA2040077A1 true CA2040077A1 (fr)	1991-10-11

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Application Number	Title	Priority Date	Filing Date
CA 2040077 Abandoned CA2040077A1 (fr)	1990-04-10	1991-04-09	Minigenes d'app recombinant pour l'expression de souris transgeniques comme modeles de la maladie d'alzheimer

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CA (1)	CA2040077A1 (fr)

1991
- 1991-04-09 CA CA 2040077 patent/CA2040077A1/fr not_active Abandoned

Legal Events

Date	Code	Title	Description
1997-04-09	FZDE	Dead

Publication	Publication Date	Title
EP0451700A1 (fr)	1991-10-16	Minigènes APP recombinants pour l'expression dans des souris transgéniques comme modèles de la maladie d'Alzheimer
US6211428B1 (en)	2001-04-03	Transgenic mouse expressing a familial form of human amyloid precursor protein
US5877015A (en)	1999-03-02	APP770 mutant in alzheimer's disease
US6037521A (en)	2000-03-14	Transgenic mouse expressing an β-Amyloid transgene
AU671093B2 (en)	1996-08-15	Transgenic animal models for alzheimer's disease
AU702293B2 (en)	1999-02-18	Transgenic animals harboring APP allele having Swedish mutation
WO1996040895A1 (fr)	1996-12-19	Procede d'identification de therapies de la maladie d'alzheimer a l'aide de modeles animaux transgeniques
US5843652A (en)	1998-12-01	Isolation and characterization of Agouti: a diabetes/obesity related gene
EP0833901A1 (fr)	1998-04-08	Procede pour identifier une therapeutique de la maladie d'alzheimer a l'aide de modeles animaux transgeniques
US5604131A (en)	1997-02-18	cDNA-genomic DNA hybrid sequence encoding APP770 containing a genomic DNA insert of the KI and OX-2 regions
AU718473B2 (en)	2000-04-13	Transgenic animal model for alzheimer disease
WO1996013513A1 (fr)	1996-05-09	Peptide d'alzheimer
US7663018B2 (en)	2010-02-16	Tau hyperphosphorylation in transgenic mice expressing the APP double mutation
JP2003535605A (ja)	2003-12-02	神経変性性障害のトランスジェニック動物モデル
JP5046413B2 (ja)	2012-10-10	ヒトｆａｄプレセニリン突然変異をもつ標的遺伝子組換え非ヒト哺乳動物および生殖による子孫
WO1994024266A1 (fr)	1994-10-27	Modeles animaux transgeniques pour la maladie d'alzheimer
AU2001276995A1 (en)	2002-05-02	Gene-targeted non-human mammal with human fad presenilin mutation and generational offspring