CA2058948A1 - Methodes de recuperation de chymosine produite par voie naturelle - Google Patents

Methodes de recuperation de chymosine produite par voie naturelle

Info

Publication number: CA2058948A1
Authority: CA; Canada
Prior art keywords: recovery; processes; naturally produced; chymosin; produced chymosin
Prior art date: 1989-06-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA2058948A

Other languages

English (en)

Other versions

CA2058948C (fr

Inventor

Henry G. Heinsohn

Jeffrey D. Lorch

Kirk J. Hayenga

Raymond E. Arnold

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Chr Hansen AS

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-13

Filing date

1990-06-13

Publication date

1990-12-14

1990-06-13 Application filed by Individual filed Critical Individual

1990-12-14 Publication of CA2058948A1 publication Critical patent/CA2058948A1/fr

1995-05-02 Application granted granted Critical

1995-05-02 Publication of CA2058948C publication Critical patent/CA2058948C/fr

2010-06-13 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

108090000746 Chymosin Proteins 0.000 title abstract 4
229940080701 chymosin Drugs 0.000 title abstract 4
GNOLWGAJQVLBSM-UHFFFAOYSA-N n,n,5,7-tetramethyl-1,2,3,4-tetrahydronaphthalen-1-amine Chemical compound C1=C(C)C=C2C(N(C)C)CCCC2=C1C GNOLWGAJQVLBSM-UHFFFAOYSA-N 0.000 title abstract 4
238000000034 method Methods 0.000 title abstract 3
238000011084 recovery Methods 0.000 title abstract 3
238000000746 purification Methods 0.000 abstract 2
108090000284 Pepsin A Proteins 0.000 abstract 1
102000057297 Pepsin A Human genes 0.000 abstract 1
239000007864 aqueous solution Substances 0.000 abstract 1
239000000356 contaminant Substances 0.000 abstract 1
229940111202 pepsin Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6478—Aspartic endopeptidases (3.4.23)
- C12N9/6481—Pepsins (3.4.23.1; 3.4.23.2; 3.4.23.3)

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Wood Science & Technology (AREA)
Biomedical Technology (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Peptides Or Proteins (AREA)
Enzymes And Modification Thereof (AREA)
Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CA002058948A 1989-06-13 1990-06-13 Methodes de recuperation de chymosine produite par voie naturelle Expired - Fee Related CA2058948C (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US36593789A	1989-06-13	1989-06-13
US365,937		1989-06-13

Publications (2)

Publication Number	Publication Date
CA2058948A1 true CA2058948A1 (fr)	1990-12-14
CA2058948C CA2058948C (fr)	1995-05-02

Family

ID=23441010

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
CA002058934A Expired - Fee Related CA2058934C (fr)	1989-06-13	1990-06-13	Procedes de recuperation de chymosine produite par voie microbienne
CA002058948A Expired - Fee Related CA2058948C (fr)	1989-06-13	1990-06-13	Methodes de recuperation de chymosine produite par voie naturelle

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
CA002058934A Expired - Fee Related CA2058934C (fr)	1989-06-13	1990-06-13	Procedes de recuperation de chymosine produite par voie microbienne

Country Status (12)

Country	Link
EP (2)	EP0477285B1 (fr)
JP (2)	JP2534587B2 (fr)
AT (2)	ATE146525T1 (fr)
AU (2)	AU624968B2 (fr)
CA (2)	CA2058934C (fr)
DE (2)	DE69029471D1 (fr)
DK (1)	DK0477284T3 (fr)
ES (2)	ES2078345T3 (fr)
FI (2)	FI98643C (fr)
NO (2)	NO914885L (fr)
NZ (1)	NZ234060A (fr)
WO (2)	WO1990015864A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ234058A (en) *	1989-06-13	1992-07-28	Genencor Int	Method of purifying chymosin using phenyl-sepharose resin
EP0477285B1 (fr) *	1989-06-13	1996-12-18	Genencor International, Inc.	Procede pour la recuperation de chymosine obtenue de fa on microbienne
US5328841A (en) *	1990-10-05	1994-07-12	Genencor International, Inc.	Methods for isolating EG III cellulase component and EG III cellulase in polyethylene glycol using inorganic salt and polyethylene glycol
CA2093422C (fr) *	1990-10-05	2001-04-03	Genencor International, Inc.	Compositions detergentes contenant des compositions de type cellulase a faible teneur en cbh i
US5290474A (en) *	1990-10-05	1994-03-01	Genencor International, Inc.	Detergent composition for treating cotton-containing fabrics containing a surfactant and a cellulase composition containing endolucanase III from trichoderma ssp
US5371198A (en) *	1991-12-16	1994-12-06	Novo Nordisk A/S	Method for protection of proteolysis-susceptible protein during protein production in a fluid medium
DK0758380T3 (da) *	1994-05-03	2005-05-30	Hansens Lab	Proces til separering af mælkekoagulationsenzymer
AU701254B2 (en) *	1994-05-03	1999-01-21	Chr. Hansen A/S	A process for separating milk clotting enzymes, and stable rennet compositions
US7390936B1 (en)	1999-08-23	2008-06-24	Sembiosys Genetics Inc.	Commercial production of chymosin in plants
US20020160445A1 (en)	2001-02-09	2002-10-31	Marianne Harboe	Method of providing polypeptide preparations with reduced enzymatic side activities
JP5043654B2 (ja) *	2004-06-29	2012-10-10	アレストレーディングソシエテアノニム	Ｉｌ−１８結合タンパク質の精製のための方法
WO2012127005A1 (fr) *	2011-03-22	2012-09-27	Dsm Ip Assets B.V.	Formulation de chymosine
ES2685402T3 (es) *	2013-07-18	2018-10-08	Chr. Hansen A/S	Composición de enzima proteasa aspártica para coagulación de leche

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2639129C3 (de) *	1976-08-31	1979-10-04	Gesellschaft Fuer Biotechnologische Forschung Mbh (Gbf), 3300 Braunschweig	Verfahren zur Abtrennung von Enzymen
GB1589581A (en) *	1976-04-14	1981-05-13	Biotechnolog Forschung Gmbh	Process for the separation of enzymes
US4743551A (en) *	1984-11-05	1988-05-10	Miles Inc.	Purification of microbial rennet from Mucor miehei
KR890003943B1 (ko) *	1985-09-04	1989-10-13	마일스 레버라토리스, 인코포레이티드	전발효 맥주로부터 세포의 효소의 회수방법
US4728613A (en) *	1985-09-04	1988-03-01	Miles Laboratories, Inc.	Method for the recovery of extracellular enzymes from whole fermentation beer
US4745063A (en) *	1986-10-01	1988-05-17	Sanofi Bio Ingredients, Inc.	Method for separating rennet components
EP0477285B1 (fr) *	1989-06-13	1996-12-18	Genencor International, Inc.	Procede pour la recuperation de chymosine obtenue de fa on microbienne

1990
- 1990-06-13 EP EP90910045A patent/EP0477285B1/fr not_active Expired - Lifetime
- 1990-06-13 DK DK90910042.2T patent/DK0477284T3/da active
- 1990-06-13 CA CA002058934A patent/CA2058934C/fr not_active Expired - Fee Related
- 1990-06-13 WO PCT/US1990/003376 patent/WO1990015864A1/fr not_active Ceased
- 1990-06-13 ES ES90910042T patent/ES2078345T3/es not_active Expired - Lifetime
- 1990-06-13 NZ NZ234060A patent/NZ234060A/en unknown
- 1990-06-13 JP JP2509119A patent/JP2534587B2/ja not_active Expired - Lifetime
- 1990-06-13 JP JP2509120A patent/JP2578384B2/ja not_active Expired - Lifetime
- 1990-06-13 AT AT90910045T patent/ATE146525T1/de not_active IP Right Cessation
- 1990-06-13 EP EP90910042A patent/EP0477284B1/fr not_active Expired - Lifetime
- 1990-06-13 AU AU58421/90A patent/AU624968B2/en not_active Ceased
- 1990-06-13 CA CA002058948A patent/CA2058948C/fr not_active Expired - Fee Related
- 1990-06-13 DE DE69029471T patent/DE69029471D1/de not_active Expired - Lifetime
- 1990-06-13 ES ES90910045T patent/ES2099097T3/es not_active Expired - Lifetime
- 1990-06-13 WO PCT/US1990/003378 patent/WO1990015866A1/fr not_active Ceased
- 1990-06-13 AU AU58427/90A patent/AU624969B2/en not_active Ceased
- 1990-06-13 DE DE69021729T patent/DE69021729T2/de not_active Expired - Fee Related
- 1990-06-13 AT AT90910042T patent/ATE126531T1/de not_active IP Right Cessation
1991
- 1991-12-10 FI FI915813A patent/FI98643C/fi not_active IP Right Cessation
- 1991-12-10 FI FI915811A patent/FI98642C/fi active
- 1991-12-12 NO NO91914885A patent/NO914885L/no unknown
- 1991-12-12 NO NO91914887A patent/NO914887L/no unknown

Also Published As

Publication number	Publication date
FI98642C (fi)	1997-07-25
DE69021729T2 (de)	1996-03-21
ATE146525T1 (de)	1997-01-15
CA2058948C (fr)	1995-05-02
FI98642B (fi)	1997-04-15
JP2578384B2 (ja)	1997-02-05
AU5842190A (en)	1991-01-08
EP0477285B1 (fr)	1996-12-18
DK0477284T3 (da)	1996-01-02
AU624968B2 (en)	1992-06-25
NO914887D0 (no)	1991-12-12
NO914887L (no)	1992-02-12
CA2058934A1 (fr)	1990-12-14
FI98643C (fi)	1997-07-25
JP2534587B2 (ja)	1996-09-18
WO1990015866A1 (fr)	1990-12-27
NO914885D0 (no)	1991-12-12
JPH05500603A (ja)	1993-02-12
EP0477285A4 (en)	1992-05-20
DE69029471D1 (de)	1997-01-30
AU624969B2 (en)	1992-06-25
AU5842790A (en)	1991-01-08
FI915813A0 (fi)	1991-12-10
EP0477284A1 (fr)	1992-04-01
EP0477285A1 (fr)	1992-04-01
FI915811A0 (fi)	1991-12-10
NZ234060A (en)	1992-02-25
EP0477284A4 (en)	1992-05-20
CA2058934C (fr)	1996-05-07
FI98643B (fi)	1997-04-15
ES2078345T3 (es)	1995-12-16
EP0477284B1 (fr)	1995-08-16
ES2099097T3 (es)	1997-05-16
JPH05500602A (ja)	1993-02-12
DE69021729D1 (de)	1995-09-21
NO914885L (no)	1991-12-12
ATE126531T1 (de)	1995-09-15
WO1990015864A1 (fr)	1990-12-27

Legal Events

Date	Code	Title	Description
1992-05-21	EEER	Examination request
1999-06-14	MKLA	Lapsed

Publication	Publication Date	Title
AU7369487A (en)	1987-12-03	Multifocal, multisurface contact lens and method
ZA946871B (en)	1995-04-24	Cell for the recovery of metals from dilute solutions.
EP0684706A4 (fr)	1996-11-20	Procede de demodulation adaptative produisant des repliques et demodulateur l'utilisant.
AU7636191A (en)	1991-11-07	Catalysts and processes useful in producing 1,3-diols and/or 3-hydroxyaldehydes
EP0657403A4 (fr)	1997-05-14	Ceramique poreuse et son procede de fabrication.
CA2058948A1 (fr)	1990-12-14	Methodes de recuperation de chymosine produite par voie naturelle
IL124645A0 (en)	1998-12-06	Process for the production of 1, 2-bis (acyloxylates)
CA2017851A1 (fr)	1990-11-30	Particules biodegradables micronisees; methode de preparation et utilisation
EP0510673A3 (en)	1993-06-23	Alkaline protease, method for producing the same, use thereof and microorganism producing the same
PL304861A1 (en)	1995-03-20	Butadiene-1,3 hydroformylation process
EP0608778A3 (fr)	1997-01-22	(co)Polycarbonate et procédé pour sa préparation.
EP0413440A3 (en)	1991-09-04	Peptidyl prolyl-cis.trans-isomerase
AU6092290A (en)	1991-04-11	Process for the recovery of gold
GR3021203T3 (en)	1996-12-31	Process for the preparation of 1,1,1,2-tetrafluoro-2-chloroethan and pentafluorethane.
EP0674939A3 (fr)	1996-02-14	Membrane pour la séparation de gaz et procédé pour sa fabrication.
EP0622450A3 (fr)	1997-02-19	Compositions détergentes et méthodes pour leur fabrication.
AU7517694A (en)	1995-02-28	Synthesis of 4,10-dinitro-2,6,8,12-tetraoxa-4,10-diazatetracyclo(5.5.0.05 ,9-03,11-)dodecane
EP1258486A3 (fr)	2004-01-07	Procédé de préparation de 2,2-difluorokétène silyl o,s-acetales et des O,S esters de l'acide alpha,alpha-difluoro-beta-silyloxy-1,3-dioxolane-4-propanoique
HUT75184A (en)	1997-04-28	Plastisol, process for producing thereof and uses thereof
GR3025168T3 (en)	1998-02-27	Process for the purification of 1,1,1,2-Tetrafluorethane.
AU5436594A (en)	1994-05-24	Method for continuous recovery of, for example, rubber and plant for the performance of the method
EP0636604A3 (fr)	1996-04-10	Procédé pour la préparation de solutions aqueuses de Bis-aminooxy-alcane pratiquement dépourvues de sels.
AU6502494A (en)	1994-12-12	Process for conditioning data, especially coded voice signal parameters
AU7072594A (en)	1995-01-17	Surfactant, process for its production and use
GR3022119T3 (en)	1997-03-31	Process for the hydroxycarbonylation of lactones.