CA2067237A1 - Plasmid and microbial cell for production of an inhibitory protein for phospholipase a2 from inflammatory sites, and the production and use of said protein - Google Patents

Plasmid and microbial cell for production of an inhibitory protein for phospholipase a2 from inflammatory sites, and the production and use of said protein

Info

Publication number: CA2067237A1
Authority: CA; Canada
Prior art keywords: dna; protein; plasmid; accordance; sequence
Prior art date: 1990-08-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002067237A

Other languages

English (en)

French (fr)

Inventor

Yorimasa Suwa

Atsushi Imaizumi

Masahiro Okada

Yoji Suzuki

Ichiro Kudo

Keizo Inoue

Chieko Azuma

Makoto Murakami

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Teijin Ltd

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-03

Filing date

1991-08-03

Publication date

1992-02-04

1991-08-03 Application filed by Individual filed Critical Individual

1992-02-04 Publication of CA2067237A1 publication Critical patent/CA2067237A1/en

Status Abandoned legal-status Critical Current

Links

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OBAMASZCXDIXSS-SZMVWBNQSA-N Trp-Glu-Lys Chemical compound C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)O)N OBAMASZCXDIXSS-SZMVWBNQSA-N 0.000 description 1
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CPGJELLYDQEDRK-NAKRPEOUSA-N Val-Ile-Ala Chemical compound CC[C@H](C)[C@H](NC(=O)[C@@H](N)C(C)C)C(=O)N[C@@H](C)C(O)=O CPGJELLYDQEDRK-NAKRPEOUSA-N 0.000 description 1
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UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Zoology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

CA002067237A 1990-08-03 1991-08-03 Plasmid and microbial cell for production of an inhibitory protein for phospholipase a2 from inflammatory sites, and the production and use of said protein Abandoned CA2067237A1 (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP2-205,164		1990-08-03
JP20516490		1990-08-03
JP41159490		1990-12-19
JP2-411,594		1990-12-19

Publications (1)

Publication Number	Publication Date
CA2067237A1 true CA2067237A1 (en)	1992-02-04

Family

ID=26514886

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002067237A Abandoned CA2067237A1 (en)	1990-08-03	1991-08-03	Plasmid and microbial cell for production of an inhibitory protein for phospholipase a2 from inflammatory sites, and the production and use of said protein

Country Status (4)

Country	Link
EP (1)	EP0495995A1 (2)
KR (1)	KR920702418A (2)
CA (1)	CA2067237A1 (2)
WO (1)	WO1992002619A1 (2)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TWI248820B (en) *	1999-03-03	2006-02-11	Nitto Denko Corp	Oral adhesive sheet and oral adhesive preparation
US7125678B2 (en)	2001-11-23	2006-10-24	Nanogen, Inc.	Protein biopolymer markers predictive of type II diabetes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1991001999A1 (fr) *	1989-08-03	1991-02-21	Teijin Limited	Proteine d'inhibition de la phospholipase a2 naissant dans une region inflammee, sa production et gene prevu a cet effet

1991
- 1991-08-03 CA CA002067237A patent/CA2067237A1/en not_active Abandoned
- 1991-08-03 KR KR1019920700763A patent/KR920702418A/ko not_active Ceased
- 1991-08-03 WO PCT/JP1991/001040 patent/WO1992002619A1/ja not_active Ceased
- 1991-08-03 EP EP91913830A patent/EP0495995A1/en not_active Withdrawn

Also Published As

Publication number	Publication date
EP0495995A4 (2)	1994-04-13
WO1992002619A1 (en)	1992-02-20
EP0495995A1 (en)	1992-07-29
KR920702418A (ko)	1992-09-04

Legal Events

Date	Code	Title	Description
1995-02-03	FZDE	Discontinued
2023-05-26	FZDE	Discontinued	Effective date: 19950203

Publication	Publication Date	Title
Waśniowska et al.	1977	The amino acids of M and N blood group glycopeptides are different
Oppenheim et al.	1986	The primary structure and functional characterization of the neutral histidine-rich polypeptide from human parotid secretion.
Simons et al.	1978	Membrane-bound and secreted forms of penicillinase from Bacillus licheniformis
Harwig et al.	1993	Purification of cysteine-rich bioactive peptides from leukocytes by continuous acid-urea-polyacrylamide gel electrophoresis
AU623180B2 (en)	1992-05-07	Biologicaly active lipoprotein and its use
JPS6222799A (ja)	1987-01-30	血液凝固阻害作用を有する新規ポリペプチド
US5013720A (en)	1991-05-07	SAP-6-Val proteins and methods
US5045462A (en)	1991-09-03	Basic protein called phospholipase A2 isolated from the venom of a snake of the family elapidae and its amino acid sequence
Niewiarowski et al.	1980	Identification and separation of secreted platelet proteins by isoelectric focusing. Evidence that low-affinity platelet factor 4 is converted to beta-thromboglobulin by limited proteolysis
CA2178894A1 (en)	1996-12-16	Parathyroid hormone derivatives and their use
EP0317053B1 (en)	1993-12-08	Trigramin- a platelet aggregation inhibiting polypeptide
JP2980334B2 (ja)	1999-11-22	ラットの顎下腺から導出したペプチド及びポリペプチド、対応するポリクローナル及びモノクローナル抗体、対応するハイブリドーマ並びに診断、検出及び治療目的でのこれらの生成物の使用
US5185431A (en)	1993-02-09	Recombinant natural killer cell activator
Klip et al.	1980	Alignment of the major tryptic fragments of the adenosine triphosphatase from sarcoplasmic reticulum.
EP0273916A1 (en)	1988-07-13	Pulmonary hydrophobic surfactant-associated protein of 6,000 daltons molecular weight and multimers thereof
HEW et al.	1986	Biosynthesis of antifreeze polypeptides in the winter flounder: characterization and seasonal occurrence of precursor polypeptides
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