CA2079934A1 - Enrobages permettant de masquer le gout de comprimes pharmaceutiques machables - Google Patents

Enrobages permettant de masquer le gout de comprimes pharmaceutiques machables

Info

Publication number: CA2079934A1
Authority: CA; Canada
Prior art keywords: rotogranules; pharmaceutical tablets; taste mask; chewable pharmaceutical; medicament
Prior art date: 1991-10-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA 2079934

Other languages

English (en)

Other versions

CA2079934C (fr

Inventor

Edward J. Roche

Susan M. Papile

Eleanor M. Freeman

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Kenvue Brands LLC

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-10-15

Filing date

1992-10-06

Publication date

1993-04-16

1992-10-06 Application filed by Individual filed Critical Individual

1993-04-16 Publication of CA2079934A1 publication Critical patent/CA2079934A1/fr

2002-09-03 Application granted granted Critical

2002-09-03 Publication of CA2079934C publication Critical patent/CA2079934C/fr

2012-10-06 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

238000000576 coating method Methods 0.000 title 1
239000003814 drug Substances 0.000 abstract 4
238000000034 method Methods 0.000 abstract 2
229920002153 Hydroxypropyl cellulose Polymers 0.000 abstract 1
GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
239000011230 binding agent Substances 0.000 abstract 1
229920002301 cellulose acetate Polymers 0.000 abstract 1
229920006217 cellulose acetate butyrate Polymers 0.000 abstract 1
XUFQPHANEAPEMJ-UHFFFAOYSA-N famotidine Chemical compound NC(N)=NC1=NC(CSCCC(N)=NS(N)(=O)=O)=CS1 XUFQPHANEAPEMJ-UHFFFAOYSA-N 0.000 abstract 1
229960001596 famotidine Drugs 0.000 abstract 1
238000005469 granulation Methods 0.000 abstract 1
230000003179 granulation Effects 0.000 abstract 1
239000001863 hydroxypropyl cellulose Substances 0.000 abstract 1
235000010977 hydroxypropyl cellulose Nutrition 0.000 abstract 1
229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
239000008101 lactose Substances 0.000 abstract 1
230000000873 masking effect Effects 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Nutrition Science (AREA)
Physiology (AREA)
Medicinal Preparation (AREA)

CA 2079934 1991-10-15 1992-10-06 Enrobages permettant de masquer le gout de comprimes pharmaceutiques machables Expired - Lifetime CA2079934C (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US777,872		1977-03-15
US77787291A	1991-10-15	1991-10-15

Publications (2)

Publication Number	Publication Date
CA2079934A1 true CA2079934A1 (fr)	1993-04-16
CA2079934C CA2079934C (fr)	2002-09-03

Family

ID=25111568

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA 2079934 Expired - Lifetime CA2079934C (fr)	1991-10-15	1992-10-06	Enrobages permettant de masquer le gout de comprimes pharmaceutiques machables

Country Status (5)

Country	Link
EP (1)	EP0538034B1 (fr)
CA (1)	CA2079934C (fr)
DE (1)	DE69209764T2 (fr)
ES (1)	ES2088550T3 (fr)
GR (1)	GR1002100B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9221414D0 (en) *	1992-10-13	1992-11-25	Glaxo Group Ltd	Pharmaceutical compositions
US5529783A (en) *	1994-12-19	1996-06-25	Mcneil-Ppc, Inc.	Rotor granulation and coating of acetaminophen, pseudoephedrine, chlorpheniramine, and, optionally dextromethorphan
US8071128B2 (en)	1996-06-14	2011-12-06	Kyowa Hakko Kirin Co., Ltd.	Intrabuccally rapidly disintegrating tablet and a production method of the tablets
US9358214B2 (en)	2001-10-04	2016-06-07	Adare Pharmaceuticals, Inc.	Timed, sustained release systems for propranolol
US8367111B2 (en)	2002-12-31	2013-02-05	Aptalis Pharmatech, Inc.	Extended release dosage forms of propranolol hydrochloride
US8545881B2 (en)	2004-04-19	2013-10-01	Eurand Pharmaceuticals, Ltd.	Orally disintegrating tablets and methods of manufacture
US8747895B2 (en)	2004-09-13	2014-06-10	Aptalis Pharmatech, Inc.	Orally disintegrating tablets of atomoxetine
US9884014B2 (en)	2004-10-12	2018-02-06	Adare Pharmaceuticals, Inc.	Taste-masked pharmaceutical compositions
AU2005299490C1 (en)	2004-10-21	2012-01-19	Adare Pharmaceuticals, Inc.	Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US9161918B2 (en)	2005-05-02	2015-10-20	Adare Pharmaceuticals, Inc.	Timed, pulsatile release systems
KR101765357B1 (ko)	2009-12-02	2017-08-04	아데어 파마수티컬스 에스.알.엘.	펙소페나딘 마이크로캡슐 및 그것을 함유하는 조성물
WO2017091166A1 (fr)	2015-11-26	2017-06-01	Pharmacti̇ve İlaç San. Ve Ti̇c. A.Ş.	Compositions pharmaceutiques stables et leur procédé de préparation
AU2022244333A1 (en)	2021-03-24	2023-11-09	Kenvue Brands Llc	A pharmaceutical composition comprising famotidine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4801461A (en) *	1987-01-28	1989-01-31	Alza Corporation	Pseudoephedrine dosage form
JPH0774166B2 (ja) *	1987-02-06	1995-08-09	信越化学工業株式会社	徐放性被覆薬剤の製造方法
NZ234587A (en) *	1989-08-04	1991-11-26	Mcneil Ppc Inc	A chewable pharmaceutical tablet of compressed coated granules
US5075114A (en) *	1990-05-23	1991-12-24	Mcneil-Ppc, Inc.	Taste masking and sustained release coatings for pharmaceuticals
CA2052679C (fr) *	1990-08-30	1997-12-02	Edward J. Roche	Rotogranulations et enrobages masquant les saveurs dans la preparation de comprimes pharmaceutiques a croquer

1992
- 1992-10-06 CA CA 2079934 patent/CA2079934C/fr not_active Expired - Lifetime
- 1992-10-12 GR GR920100438A patent/GR1002100B/el not_active IP Right Cessation
- 1992-10-15 DE DE1992609764 patent/DE69209764T2/de not_active Expired - Lifetime
- 1992-10-15 ES ES92309413T patent/ES2088550T3/es not_active Expired - Lifetime
- 1992-10-15 EP EP19920309413 patent/EP0538034B1/fr not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA2079934C (fr)	2002-09-03
GR1002100B (en)	1995-12-29
ES2088550T3 (es)	1996-08-16
DE69209764D1 (de)	1996-05-15
GR920100438A (el)	1993-06-30
EP0538034B1 (fr)	1996-04-10
EP0538034A1 (fr)	1993-04-21
DE69209764T2 (de)	1996-09-05

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Legal Events

Date	Code	Title	Description
1999-05-31	EEER	Examination request
2012-10-09	MKEX	Expiry