CA2091360A1 - Fuorate de mometasone monohydrate, son procede de fabrication et ses compositions pharmaceutiques - Google Patents

Fuorate de mometasone monohydrate, son procede de fabrication et ses compositions pharmaceutiques

Info

Publication number: CA2091360A1
Authority: CA; Canada
Prior art keywords: mometasone furoate; pharmaceutical compositions; making same; furoate monohydrate; monohydrate
Prior art date: 1990-09-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA2091360A

Other languages

English (en)

Other versions

CA2091360C (fr

Inventor

Pui-Ho Yuen

Charles Eckhart

Teresa Etlinger

Nancy Levine

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merck Sharp and Dohme LLC

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-09-10

Filing date

1991-09-06

Publication date

1992-03-11

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24320279&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2091360(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1991-09-06 Application filed by Individual filed Critical Individual

1992-03-11 Publication of CA2091360A1 publication Critical patent/CA2091360A1/fr

1997-04-08 Application granted granted Critical

1997-04-08 Publication of CA2091360C publication Critical patent/CA2091360C/fr

2011-09-06 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

CA002091360A 1990-09-10 1991-09-06 Fuorate de mometasone monohydrate, son procede de fabrication et ses compositions pharmaceutiques Expired - Lifetime CA2091360C (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US58023990A	1990-09-10	1990-09-10
US580,239		1990-09-10

Publications (2)

Publication Number	Publication Date
CA2091360A1 true CA2091360A1 (fr)	1992-03-11
CA2091360C CA2091360C (fr)	1997-04-08

Family

ID=24320279

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002091360A Expired - Lifetime CA2091360C (fr)	1990-09-10	1991-09-06	Fuorate de mometasone monohydrate, son procede de fabrication et ses compositions pharmaceutiques

Country Status (35)

Country	Link
US (1)	US6180781B1 (fr)
EP (1)	EP0548114B1 (fr)
JP (1)	JPH0725789B2 (fr)
KR (1)	KR960013445B1 (fr)
CN (1)	CN1030920C (fr)
AT (1)	ATE113604T1 (fr)
AU (1)	AU663471B2 (fr)
BG (1)	BG60755B2 (fr)
CA (1)	CA2091360C (fr)
CZ (1)	CZ281318B6 (fr)
DE (2)	DE69104991T2 (fr)
DK (1)	DK0548114T5 (fr)
EE (1)	EE02962B1 (fr)
ES (1)	ES2065701T3 (fr)
FI (1)	FI111078B (fr)
HK (1)	HK185996A (fr)
HR (1)	HRP920383B1 (fr)
HU (1)	HU213401B (fr)
IE (1)	IE67056B1 (fr)
IL (1)	IL99437A (fr)
LU (1)	LU90366I2 (fr)
MX (2)	MX9203396A (fr)
MY (1)	MY106644A (fr)
NL (1)	NL980012I2 (fr)
NO (1)	NO300548B1 (fr)
NZ (1)	NZ239711A (fr)
OA (1)	OA09772A (fr)
PH (1)	PH30443A (fr)
PL (1)	PL165803B1 (fr)
PT (1)	PT98905B (fr)
SI (1)	SI9111497A (fr)
TW (2)	TW272195B (fr)
WO (1)	WO1992004365A1 (fr)
YU (1)	YU48666B (fr)
ZA (1)	ZA917148B (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL165803B1 (pl) *	1990-09-10	1995-02-28	Schering Corp	Sposób wytwarzania nowego monohydratu 9a, 21-dichloro-16-a metylo-1,4-pregnadieno-11 ß , 17a-diolo-3,20-diono-17-(2’furanokarboksylanu) PL PL PL PL
PE44995A1 (es) *	1994-01-27	1995-12-18	Schering Corp	Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias
US5837699A (en)	1994-01-27	1998-11-17	Schering Corporation	Use of mometasone furoate for treating upper airway passage diseases
US5886200A (en) *	1996-07-01	1999-03-23	Schering Corporation	Process for the preparation of 17-esters of 9 α, 21-dihalo-pregnane-11 β, 17 α-diol-20-ones
US5976573A (en)	1996-07-03	1999-11-02	Rorer Pharmaceutical Products Inc.	Aqueous-based pharmaceutical composition
CN1059476C (zh) *	1996-08-21	2000-12-13	邓维鹏	金黄色铝合金硒盐电解着色方法
DE69804998T2 (de) *	1997-10-09	2002-12-12	Schering Corp., Kenilworth	Mometasonfuroat-suspensionen zum zerstäuben
US6187765B1 (en) *	1997-10-09	2001-02-13	Schering Corporation	Mometasone furoate suspensions for nebulization
MY133181A (en) *	1998-09-10	2007-10-31	Schering Corp	Methods and compositions for treating sinusitis, otitis media and other related disorders using antihistamines
CZ20013912A3 (cs)	1999-05-04	2002-05-15	Strakan Limited	Androgen glykosid, sloučenina, testosteron-ß-D-glukosid, 5 alfa-Dihydrotestosteron- 17ß-D-glukosid, farmaceutický prostředek a pouľití sloučeniny
GB0207906D0 (en) *	2002-04-05	2002-05-15	3M Innovative Properties Co	Formoterol and mometasone aerosol formulations
US9808471B2 (en)	2003-04-16	2017-11-07	Mylan Specialty Lp	Nasal pharmaceutical formulations and methods of using the same
US8912174B2 (en)	2003-04-16	2014-12-16	Mylan Pharmaceuticals Inc.	Formulations and methods for treating rhinosinusitis
US7811606B2 (en)	2003-04-16	2010-10-12	Dey, L.P.	Nasal pharmaceutical formulations and methods of using the same
US7825147B2 (en) *	2003-08-29	2010-11-02	Ranbaxy Laboratories Limited	Inhibitors of phosphodiesterase type-IV
US20070259874A1 (en) *	2003-11-26	2007-11-08	Palle Venkata P	Phosphodiesterase Inhibitors
US7491725B2 (en)	2004-02-06	2009-02-17	Bristol-Myers Squibb Company	Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
US7915286B2 (en)	2005-09-16	2011-03-29	Ranbaxy Laboratories Limited	Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors
US20070099883A1 (en) *	2005-10-07	2007-05-03	Cheryl Lynn Calis	Anhydrous mometasone furoate formulation
WO2007045979A1 (fr)	2005-10-19	2007-04-26	Ranbaxy Laboratories Limited	Compositions pharmaceutiques d'antagonistes du recepteur muscarinique
CA2626628A1 (fr) *	2005-10-19	2007-04-26	Ranbaxy Laboratories Limited	Compositions d'inhibiteurs de la phosphodiesterase de type iv
CN100436473C (zh) *	2005-12-09	2008-11-26	天津药业集团有限公司	糠酸莫美他松中间体21-酯及制法
CN100389121C (zh) *	2005-12-09	2008-05-21	天津药业集团有限公司	糠酸莫美他松中间体21-羟的制备方法
DE102006034883A1 (de) *	2006-07-25	2008-01-31	Hermal Kurt Herrmann Gmbh & Co. Ohg	Pharmazeutische Zusammensetzung enthaltend Mometasonfuroat
MX2009003100A (es) *	2006-09-22	2009-05-11	Ranbaxy Lab Ltd	Inhibidores de fosfodiesterasa tipo iv.
US20100029728A1 (en) *	2006-09-22	2010-02-04	Ranbaxy Laboratories Limited	Phosphodiesterase inhibitors
US20080207659A1 (en) *	2007-02-15	2008-08-28	Asit Kumar Chakraborti	Inhibitors of phosphodiesterase type 4
US20110130403A1 (en) *	2007-03-14	2011-06-02	Ranbaxy Laboratories Limited	Pyrazolo [3, 4-b] pyridine derivatives as phosphodiesterase inhibitors
PT2124944E (pt) *	2007-03-14	2012-05-17	Ranbaxy Lab Ltd	Derivados de pirazolo[3,4-b]piridina como inibidores de fosfodiesterase
EP2111861A1 (fr)	2008-04-21	2009-10-28	Ranbaxy Laboratories Limited	Compositions d'inhibiteurs de type IV de la phosphodiestérase
AU2010253770B9 (en)	2009-05-29	2015-02-12	Pearl Therapeutics, Inc.	Compositions for respiratory delivery of active agents and associated methods and systems
US8815258B2 (en) *	2009-05-29	2014-08-26	Pearl Therapeutics, Inc.	Compositions, methods and systems for respiratory delivery of two or more active agents
PT105058B (pt)	2010-04-21	2013-04-17	Hovione Farmaciencia S A	Processo para processamento de partículas de ingredientes activos farmacêuticos
US20140275517A1 (en)	2013-03-15	2014-09-18	Pearl Therapeutics, Inc.	Methods and systems for conditioning of particulate crystalline materials
CN107260671B (zh) *	2016-04-08	2021-03-26	天津金耀集团有限公司	一种糠酸莫米松混悬鼻喷剂组合物
CN107266518B (zh) *	2016-04-08	2021-03-30	天津金耀集团有限公司	一种糠酸莫米松晶型及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CY1359A (en) *	1981-02-02	1987-08-07	Schering Corp	Aromatic heterocyclic esters of steroids, their preparation and pharmaceutical compositions containing them
US4783444A (en)	1984-09-17	1988-11-08	Schering Corporation	Antiglaucoma compositions and methods
US4808610A (en) *	1986-10-02	1989-02-28	Schering Corporation	Mometasone furoate anti-inflammatory cream composition using hexylene glycol
US4775529A (en) *	1987-05-21	1988-10-04	Schering Corporation	Steroid lotion
PL165803B1 (pl) *	1990-09-10	1995-02-28	Schering Corp	Sposób wytwarzania nowego monohydratu 9a, 21-dichloro-16-a metylo-1,4-pregnadieno-11 ß , 17a-diolo-3,20-diono-17-(2’furanokarboksylanu) PL PL PL PL

1991
- 1991-09-06 PL PL91298223A patent/PL165803B1/pl unknown
- 1991-09-06 IL IL9943791A patent/IL99437A/en not_active IP Right Cessation
- 1991-09-06 AT AT91915453T patent/ATE113604T1/de active
- 1991-09-06 ES ES91915453T patent/ES2065701T3/es not_active Expired - Lifetime
- 1991-09-06 CA CA002091360A patent/CA2091360C/fr not_active Expired - Lifetime
- 1991-09-06 MX MX9203396A patent/MX9203396A/es unknown
- 1991-09-06 EP EP91915453A patent/EP0548114B1/fr not_active Expired - Lifetime
- 1991-09-06 AU AU84974/91A patent/AU663471B2/en not_active Expired
- 1991-09-06 DE DE69104991T patent/DE69104991T2/de not_active Expired - Lifetime
- 1991-09-06 CZ CZ93383A patent/CZ281318B6/cs not_active IP Right Cessation
- 1991-09-06 DE DE1991604991 patent/DE19875032I2/de active Active
- 1991-09-06 DK DK91915453.4T patent/DK0548114T5/da active
- 1991-09-06 HU HU9300685A patent/HU213401B/hu unknown
- 1991-09-06 WO PCT/US1991/006249 patent/WO1992004365A1/fr not_active Ceased
- 1991-09-06 KR KR1019930700702A patent/KR960013445B1/ko not_active Expired - Lifetime
- 1991-09-06 JP JP3514768A patent/JPH0725789B2/ja not_active Expired - Lifetime
- 1991-09-09 TW TW083106101A patent/TW272195B/zh not_active IP Right Cessation
- 1991-09-09 IE IE315591A patent/IE67056B1/en not_active IP Right Cessation
- 1991-09-09 ZA ZA917148A patent/ZA917148B/xx unknown
- 1991-09-09 YU YU149791A patent/YU48666B/sh unknown
- 1991-09-09 PT PT98905A patent/PT98905B/pt not_active IP Right Cessation
- 1991-09-09 PH PH43072A patent/PH30443A/en unknown
- 1991-09-09 SI SI9111497A patent/SI9111497A/sl unknown
- 1991-09-09 TW TW080107102A patent/TW229208B/zh not_active IP Right Cessation
- 1991-09-09 MY MYPI91001630A patent/MY106644A/en unknown
- 1991-09-09 NZ NZ239711A patent/NZ239711A/en not_active IP Right Cessation
- 1991-09-09 MX MX9100990A patent/MX9100990A/es unknown
- 1991-09-10 CN CN91108910A patent/CN1030920C/zh not_active Expired - Lifetime
1992
- 1992-09-21 HR HRP-1497/91A patent/HRP920383B1/xx not_active IP Right Cessation
1993
- 1993-02-26 NO NO930693A patent/NO300548B1/no not_active IP Right Cessation
- 1993-03-09 OA OA60348A patent/OA09772A/en unknown
- 1993-03-09 FI FI931031A patent/FI111078B/fi not_active IP Right Cessation
1994
- 1994-02-24 BG BG098564A patent/BG60755B2/bg unknown
- 1994-11-21 EE EE9400388A patent/EE02962B1/xx unknown
1995
- 1995-04-17 US US08/422,479 patent/US6180781B1/en not_active Expired - Lifetime
1996
- 1996-10-03 HK HK185996A patent/HK185996A/en not_active IP Right Cessation
1998
- 1998-03-12 NL NL980012C patent/NL980012I2/nl unknown
1999
- 1999-03-05 LU LU90366C patent/LU90366I2/fr unknown

Also Published As

Publication number	Publication date
MX9100990A (es)	1992-05-04
YU149791A (sh)	1994-01-20
DK0548114T5 (da)	1995-01-30
AU8497491A (en)	1992-03-30
HK185996A (en)	1996-10-11
NL980012I1 (nl)	1998-05-06
HRP920383B1 (en)	2000-04-30
SI9111497A (sl)	1998-04-30
MX9203396A (es)	1992-07-31
OA09772A (en)	1993-11-30
TW272195B (fr)	1996-03-11
IL99437A0 (en)	1992-08-18
HRP920383A2 (en)	1998-06-30
CZ281318B6 (cs)	1996-08-14
HUT64361A (en)	1993-12-28
NO930693D0 (no)	1993-02-26
BG60755B2 (bg)	1996-02-29
CZ38393A3 (en)	1994-01-19
IE913155A1 (en)	1992-03-11
HU9300685D0 (en)	1993-06-28
ATE113604T1 (de)	1994-11-15
HU213401B (en)	1997-06-30
EE02962B1 (et)	1997-02-17
LU90366I2 (fr)	1999-05-05
ES2065701T3 (es)	1995-02-16
AU663471B2 (en)	1995-10-12
NO930693L (no)	1993-02-26
PL165803B1 (pl)	1995-02-28
EP0548114A1 (fr)	1993-06-30
MY106644A (en)	1995-07-31
JPH05506667A (ja)	1993-09-30
FI931031A0 (fi)	1993-03-09
ZA917148B (en)	1992-08-26
DE19875032I2 (de)	2007-04-19
IE67056B1 (en)	1996-02-21
FI111078B (fi)	2003-05-30
CA2091360C (fr)	1997-04-08
NL980012I2 (nl)	2004-11-01
NZ239711A (en)	1992-09-25
CN1030920C (zh)	1996-02-07
IL99437A (en)	1995-05-29
PH30443A (en)	1997-05-09
TW229208B (fr)	1994-09-01
NO300548B1 (no)	1997-06-16
EP0548114B1 (fr)	1994-11-02
US6180781B1 (en)	2001-01-30
YU48666B (sh)	1999-06-15
DE69104991T2 (de)	1995-04-20
KR960013445B1 (ko)	1996-10-05
DE69104991D1 (de)	1994-12-08
PT98905B (pt)	1998-08-31
CN1059911A (zh)	1992-04-01
FI931031L (fi)	1993-03-09
PT98905A (pt)	1992-09-30
WO1992004365A1 (fr)	1992-03-19
JPH0725789B2 (ja)	1995-03-22

Legal Events

Date	Code	Title	Description
1993-03-09	EEER	Examination request
2011-09-06	MKEX	Expiry

Publication	Publication Date	Title
TW229208B (fr)	1994-09-01
IL100899A0 (en)	1992-11-15	Beta-amino-alpha-hydroxycarboxylic acid derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
CA2150251A1 (fr)	1994-11-10	Lyospheres contenant de la gonadotropine
CA2172616A1 (fr)	1995-02-16	Tropyl 7-azaindol-3-ylcarboxamides, antitussifs
CA2163837A1 (fr)	1996-06-14	Hydrates de paclitaxel cristallises
IL105348A0 (en)	1993-08-18	Azabicyclo derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL92425A0 (en)	1990-07-26	Alpha-d-glucofuranose derivatives,pharmaceutical compositions containing the same and processes for the preparation thereof
CA2152771A1 (fr)	1996-01-29	Derives 7-o-ether de taxane
IL107358A0 (en)	1994-01-25	a-Phosphonosulfonate derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same
IL102116A0 (en)	1993-01-14	Hetaryloxy-beta-carboline derivatives,processes for the preparation thereof,and pharmaceutical compositions containing the same
IL98196A0 (en)	1992-06-21	Cephalosporin derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL99551A0 (en)	1992-08-18	Tricyclic compounds,processes for the preparation thereof and pharmaceutical compositions containing the same
HRP940315A2 (en)	1996-08-31	Process for the preparation of pharmaceutical compositions containinbg active ingredient
IL99389A0 (en)	1992-08-18	Amino acid derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL101566A0 (en)	1992-12-30	Isoxazolylimidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL90191A0 (en)	1989-12-15	3-pyrrolidinylthio-1-azabicyclo-(3.2.0)hept-2-ene-2-carboxylic acid derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL107359A0 (en)	1994-01-25	Cephem derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
AU3101593A (en)	1993-07-08	New pyridylsulphonylurea compound, processes for the preparation thereof, and pharmaceutical compositions containing it
AU6991291A (en)	1991-07-25	3-l-(5-thioxo-l-prolyl) thiazolidine-4-carboxylic acid and derivatives therefrom, processes for the preparation thereof and pharmaceutical compositions containing them
ZA912180B (en)	1992-10-28	Novel compounds.cephalosporins,process for their preparation and pharmaceutical compositions containing them
AU3695393A (en)	1993-10-21	New arylpiperidine derivative, process for the preparation thereof and pharmaceutical compositions containing it
AU5695594A (en)	1994-07-04	Thio- and oxo-azasteroids, processes for the preparation thereof, use thereof as antiandrogens and pharmaceutical compositions containing them
ZA914046B (en)	1992-03-25	New berbane derivatives,pharmaceutical compositions containing these compounds and process for the preparation of same
IL98314A0 (en)	1992-06-21	New berbane derivatives,pharmaceutical compositions containing these compounds and process for the preparation of same