CA2093361C - Derive porphyrine - Google Patents

Derive porphyrine Download PDF

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Publication number
CA2093361C
CA2093361C CA002093361A CA2093361A CA2093361C CA 2093361 C CA2093361 C CA 2093361C CA 002093361 A CA002093361 A CA 002093361A CA 2093361 A CA2093361 A CA 2093361A CA 2093361 C CA2093361 C CA 2093361C
Authority
CA
Canada
Prior art keywords
hpix
methanamide
ether
hydroxymethyl
mpix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002093361A
Other languages
English (en)
Other versions
CA2093361A1 (fr
Inventor
Michel Ringuet
Roy H. Pottier
James C. Kennedy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Queens University at Kingston
Original Assignee
Queens University at Kingston
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Queens University at Kingston filed Critical Queens University at Kingston
Publication of CA2093361A1 publication Critical patent/CA2093361A1/fr
Application granted granted Critical
Publication of CA2093361C publication Critical patent/CA2093361C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA002093361A 1990-10-05 1991-10-01 Derive porphyrine Expired - Fee Related CA2093361C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US59386790A 1990-10-05 1990-10-05
US593,867 1990-10-05
PCT/CA1991/000346 WO1992006097A1 (fr) 1990-10-05 1991-10-01 Derives de prophyrine

Publications (2)

Publication Number Publication Date
CA2093361A1 CA2093361A1 (fr) 1992-04-06
CA2093361C true CA2093361C (fr) 2002-04-23

Family

ID=24376530

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002093361A Expired - Fee Related CA2093361C (fr) 1990-10-05 1991-10-01 Derive porphyrine

Country Status (6)

Country Link
EP (1) EP0553116A1 (fr)
AU (1) AU655942B2 (fr)
CA (1) CA2093361C (fr)
MX (1) MX9101448A (fr)
NZ (1) NZ240057A (fr)
WO (1) WO1992006097A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5493017A (en) * 1992-08-14 1996-02-20 The Trustees Of The University Of Pennsylvania Ring-metalated porphyrins
US5599924A (en) * 1992-08-14 1997-02-04 Trustees Of The University Of Pennsylvania Electron-deficient porphyrins and processes and intermediates for preparing same
US5371199B1 (en) * 1992-08-14 1995-12-26 Univ Pennsylvania Substituted porphyrins porphyrin-containing polymers and synthetic methods therefor
US5817830A (en) * 1992-08-14 1998-10-06 Trustees Of The University Of Pennsylvania Pyrrolic compounds
EP0758907A1 (fr) * 1994-05-11 1997-02-26 Schering Aktiengesellschaft Utilisation de composes a base d'un complexe de porphyrine ou d'un complexe de porphyrine etendue comme preparation diagnostique pour la localisation d'un infarctus
US6013241A (en) * 1995-01-23 2000-01-11 Schering Aktiengesellschaft Use of porphyrin-complex or expanded porphyrin-complex compounds as an infarction localization diagnosticum
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
HU225148B1 (en) * 1995-03-10 2006-07-28 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy or diagnosis, products and kits comprising thereof and method of in vitro diagnosis by their using
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
GB9700396D0 (en) 1997-01-10 1997-02-26 Photocure As Photochemotherapeutic compositions
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
JP4307070B2 (ja) 2000-11-17 2009-08-05 バイオモーダ・インコーポレーテツド ５，１０，１５，２０−テトラキス（カルボキシフェニル）ポルフィンを使用する、細胞および組織サンプルにおける前がん症状を検出するための組成物および方法
CA2448570A1 (fr) 2001-05-31 2002-12-05 Miravant Pharmaceuticals, Inc. Derives porphyrine et azaporphyrine substitues et utilisation en therapie photodynamique, radioimagerie, et diagnostic par irm
CN103168234B (zh) 2009-07-17 2015-11-25 保爱菲技术公司 用于分析被5，10，15，20四(4-羧基苯基)卟吩(tcpp)标记的样品的系统和方法
EP3471774A4 (fr) 2016-06-16 2020-04-15 Oncoselect Therapeutics, LLC Composés de porphyrine et compositions utiles pour le traitement du cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675338A (en) * 1984-07-18 1987-06-23 Nippon Petrochemicals Co., Ltd. Tetrapyrrole therapeutic agents
US4693885A (en) * 1984-07-18 1987-09-15 Nippon Petrochemicals Co., Ltd. Tetrapyrrole therapeutic agents
WO1986001720A1 (fr) * 1984-09-13 1986-03-27 Cytogen Corporation Conjugues d'agents therapeutiques-anticorps
US4656186A (en) * 1985-04-30 1987-04-07 Nippon Petrochemicals Co., Ltd. Tetrapyrrole therapeutic agents
US4886484A (en) * 1989-06-02 1989-12-12 Litens Automotive Partnership Torsional spring tensioner with stabilizer

Also Published As

Publication number Publication date
EP0553116A1 (fr) 1993-08-04
NZ240057A (en) 1994-07-26
CA2093361A1 (fr) 1992-04-06
AU655942B2 (en) 1995-01-19
MX9101448A (es) 1992-06-05
AU8612291A (en) 1992-04-28
WO1992006097A1 (fr) 1992-04-16

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