CA2101241C - Ciprofloxacine encapsulee dans des liposomes - Google Patents

Ciprofloxacine encapsulee dans des liposomes

Info

Publication number
CA2101241C
CA2101241C CA 2101241 CA2101241A CA2101241C CA 2101241 C CA2101241 C CA 2101241C CA 2101241 CA2101241 CA 2101241 CA 2101241 A CA2101241 A CA 2101241A CA 2101241 C CA2101241 C CA 2101241C
Authority
CA
Canada
Prior art keywords
ciprofloxacin
mice
liposomes
lipids
antibiotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA 2101241
Other languages
English (en)
Other versions
CA2101241A1 (fr
Inventor
Jonathan P. Wong
Vincent L. Dininno
John W. Cherwonogrodzky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Department of National Defence
Original Assignee
Department of National Defence
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Department of National Defence filed Critical Department of National Defence
Priority to CA 2101241 priority Critical patent/CA2101241C/fr
Priority to EP94305331A priority patent/EP0652008A1/fr
Publication of CA2101241A1 publication Critical patent/CA2101241A1/fr
Application granted granted Critical
Publication of CA2101241C publication Critical patent/CA2101241C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA 2101241 1993-07-23 1993-07-23 Ciprofloxacine encapsulee dans des liposomes Expired - Lifetime CA2101241C (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA 2101241 CA2101241C (fr) 1993-07-23 1993-07-23 Ciprofloxacine encapsulee dans des liposomes
EP94305331A EP0652008A1 (fr) 1993-07-23 1994-07-20 Ciprofloxacin encapsulé en liposômes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA 2101241 CA2101241C (fr) 1993-07-23 1993-07-23 Ciprofloxacine encapsulee dans des liposomes

Publications (2)

Publication Number Publication Date
CA2101241A1 CA2101241A1 (fr) 1995-01-24
CA2101241C true CA2101241C (fr) 1998-12-22

Family

ID=4151982

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2101241 Expired - Lifetime CA2101241C (fr) 1993-07-23 1993-07-23 Ciprofloxacine encapsulee dans des liposomes

Country Status (2)

Country Link
EP (1) EP0652008A1 (fr)
CA (1) CA2101241C (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9402845B2 (en) 2005-12-08 2016-08-02 Insmed Incorporated Lipid-based compositions of antiinfectives for treating pulmonary infections and methods of use thereof
US9987227B2 (en) 2013-10-22 2018-06-05 Aradigm Corporation Inhaled surfactant-modified liposomal formulations providing both an immediate and sustained release profile
US10064882B2 (en) 2007-05-07 2018-09-04 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US10124066B2 (en) 2012-11-29 2018-11-13 Insmed Incorporated Stabilized vancomycin formulations
US10238675B2 (en) 2014-05-15 2019-03-26 Insmed Incorporated Methods for treating pulmonary non-tuberculous mycobacterial infections
US11571386B2 (en) 2018-03-30 2023-02-07 Insmed Incorporated Methods for continuous manufacture of liposomal drug products
US12521345B1 (en) 2018-05-02 2026-01-13 Insmed Incorporated Large-scale manufacturing methods for aminoglycosides

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972379A (en) * 1995-02-14 1999-10-26 Sequus Pharmaceuticals, Inc. Liposome composition and method for administering a quinolone
US6221386B1 (en) 1996-03-08 2001-04-24 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence Use of virulence factors of pathogens to improve liposomal delivery of therapeutic agents
ES2130056B1 (es) * 1997-01-16 2000-02-01 Lipotec Sa Un nuevo preparado farmaceutico para mejorar la biodisponibilidad oral de drogas de dificil absorcion.
US6565882B2 (en) 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
US6667042B2 (en) * 2000-02-24 2003-12-23 Advancis Pharmaceutical Corp. Fluroquinilone antibiotic product, use and formulation thereof
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6991807B2 (en) 2000-02-24 2006-01-31 Advancis Pharmaceutical, Corp. Antibiotic composition
US6541014B2 (en) 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20020197314A1 (en) 2001-02-23 2002-12-26 Rudnic Edward M. Anti-fungal composition
CA2533178C (fr) 2003-07-21 2014-03-11 Advancis Pharmaceutical Corporation Produit antibiotique, son utilisation et sa formulation
JP2006528185A (ja) 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
JP2006528190A (ja) 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
WO2005016311A1 (fr) 2003-08-11 2005-02-24 Advancis Pharmaceutical Corporation Pastille robuste
AU2004264356B2 (en) 2003-08-12 2011-01-27 Shionogi, Inc. Antibiotic product, use and formulation thereof
JP5686494B2 (ja) 2003-08-29 2015-03-18 シオノギ インコーポレイテッド 抗生物質製剤、その使用法及び作成方法
EP1663169A4 (fr) 2003-09-15 2010-11-24 Middlebrook Pharmaceuticals In Antibiotique, son utilisation et sa formulation
ES2254027B1 (es) * 2004-11-26 2007-07-01 Italfarmaco, S.A. Formulaciones liposomales.
US20070224255A1 (en) * 2004-04-02 2007-09-27 Italfarmaco, S.A. Liposomal Formulations
WO2006014427A1 (fr) 2004-07-02 2006-02-09 Advancis Pharmaceutical Corporation Comprimé pour distribution par impulsion
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
US8119156B2 (en) 2006-10-24 2012-02-21 Aradigm Corporation Dual action, inhaled formulations providing both an immediate and sustained release profile
US8268347B1 (en) 2006-10-24 2012-09-18 Aradigm Corporation Dual action, inhaled formulations providing both an immediate and sustained release profile
US8071127B2 (en) 2006-10-24 2011-12-06 Aradigm Corporation Dual action, inhaled formulations providing both an immediate and sustained release profile
RU2016143591A (ru) 2014-04-08 2018-05-08 Арадайм Корпорейшн Липосомы, в которых образуются нанокристаллы лекарственного вещества после замораживания-оттаивания
CN116115576A (zh) * 2022-12-30 2023-05-16 成都市妇女儿童中心医院 一种功能化的载双药脂质体纳米粒子及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201010A (en) * 1981-06-19 1986-02-21 Ciba Geigy Ag The treatment of inflammation diseases using desferrioxamine
WO1991009616A1 (fr) * 1989-12-22 1991-07-11 Yale University Antibiotiques a la quinolone encapsules dans des vesicules de lipides

Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10328071B2 (en) 2005-12-08 2019-06-25 Insmed Incorporated Lipid-based compositions of antiinfectives for treating pulmonary infections and methods of use thereof
US9511082B2 (en) 2005-12-08 2016-12-06 Insmed Incorporated Lipid-based compositions of antiinfectives for treating pulmonary infections and methods of use thereof
US9549925B2 (en) 2005-12-08 2017-01-24 Insmed Incorporated Lipid-based compositions of antiinfectives for treating pulmonary infections and methods of use thereof
US9549939B2 (en) 2005-12-08 2017-01-24 Insmed Incorporated Lipid-based compositions of antiinfectives for treating pulmonary infections and methods of use thereof
US9402845B2 (en) 2005-12-08 2016-08-02 Insmed Incorporated Lipid-based compositions of antiinfectives for treating pulmonary infections and methods of use thereof
US10064882B2 (en) 2007-05-07 2018-09-04 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US10124066B2 (en) 2012-11-29 2018-11-13 Insmed Incorporated Stabilized vancomycin formulations
US10471149B2 (en) 2012-11-29 2019-11-12 Insmed Incorporated Stabilized vancomycin formulations
US9987227B2 (en) 2013-10-22 2018-06-05 Aradigm Corporation Inhaled surfactant-modified liposomal formulations providing both an immediate and sustained release profile
US10588918B2 (en) 2014-05-15 2020-03-17 Insmed Incorporated Methods for treating pulmonary non-tuberculous mycobacterial infections
US11446318B2 (en) 2014-05-15 2022-09-20 Insmed Incorporated Methods for treating pulmonary non-tuberculous mycobacterial infections
US10251900B2 (en) 2014-05-15 2019-04-09 Insmed Incorporated Methods for treating pulmonary non-tuberculous mycobacterial infections
US10238675B2 (en) 2014-05-15 2019-03-26 Insmed Incorporated Methods for treating pulmonary non-tuberculous mycobacterial infections
US10751355B2 (en) 2014-05-15 2020-08-25 Insmed Incorporated Methods for treating pulmonary non-tuberculous mycobacterial infections
US10828314B2 (en) 2014-05-15 2020-11-10 Insmed Incorporated Methods for treating pulmonary non-tuberculous mycobacterial infections
US11395830B2 (en) 2014-05-15 2022-07-26 Insmed Incorporated Methods for treating pulmonary non-tuberculous mycobacterial infections
US10398719B2 (en) 2014-05-15 2019-09-03 Insmed Incorporated Methods for treating pulmonary non-tuberculous mycobacterial infections
US12616708B2 (en) 2014-05-15 2026-05-05 Insmed Incorporated Methods for treating pulmonary non-tuberculous mycobacterial infections
US12016873B2 (en) 2014-05-15 2024-06-25 Insmed Incorporated Methods for treating pulmonary non-tuberculous mycobacterial infections
US12168021B2 (en) 2014-05-15 2024-12-17 Insmed Incorporated Methods for treating pulmonary non-tuberculous mycobacterial infections
US12168022B2 (en) 2014-05-15 2024-12-17 Insmed Incorporated Methods for treating pulmonary non-tuberculous mycobacterial infections
US12377114B2 (en) 2014-05-15 2025-08-05 Insmed Incorporated Methods for treating pulmonary non-tuberculous mycobacterial infections
US12290600B2 (en) 2018-03-30 2025-05-06 Insmed Incorporated Methods for continuous manufacture of liposomal drug products
US11571386B2 (en) 2018-03-30 2023-02-07 Insmed Incorporated Methods for continuous manufacture of liposomal drug products
US12521345B1 (en) 2018-05-02 2026-01-13 Insmed Incorporated Large-scale manufacturing methods for aminoglycosides

Also Published As

Publication number Publication date
CA2101241A1 (fr) 1995-01-24
EP0652008A1 (fr) 1995-05-10

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