CA2108113C - Sequence d'adn codant pour des enzymes de la synthese de l'acide clavulanique - Google Patents

Sequence d'adn codant pour des enzymes de la synthese de l'acide clavulanique Download PDF

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Publication number
CA2108113C
CA2108113C CA 2108113 CA2108113A CA2108113C CA 2108113 C CA2108113 C CA 2108113C CA 2108113 CA2108113 CA 2108113 CA 2108113 A CA2108113 A CA 2108113A CA 2108113 C CA2108113 C CA 2108113C
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CA
Canada
Prior art keywords
dna molecule
amino acid
acid sequence
isolated
nucleotide sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA 2108113
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English (en)
Other versions
CA2108113A1 (fr
Inventor
Susan E. Jensen
Kwamena A. Aidoo
Ashish S. Paradkar
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University of Alberta
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University of Alberta
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Application filed by University of Alberta filed Critical University of Alberta
Priority to CA 2108113 priority Critical patent/CA2108113C/fr
Publication of CA2108113A1 publication Critical patent/CA2108113A1/fr
Application granted granted Critical
Publication of CA2108113C publication Critical patent/CA2108113C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms

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  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA 2108113 1993-10-08 1993-10-08 Sequence d'adn codant pour des enzymes de la synthese de l'acide clavulanique Expired - Fee Related CA2108113C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA 2108113 CA2108113C (fr) 1993-10-08 1993-10-08 Sequence d'adn codant pour des enzymes de la synthese de l'acide clavulanique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA 2108113 CA2108113C (fr) 1993-10-08 1993-10-08 Sequence d'adn codant pour des enzymes de la synthese de l'acide clavulanique

Publications (2)

Publication Number Publication Date
CA2108113A1 CA2108113A1 (fr) 1995-04-09
CA2108113C true CA2108113C (fr) 2006-12-05

Family

ID=4152430

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2108113 Expired - Fee Related CA2108113C (fr) 1993-10-08 1993-10-08 Sequence d'adn codant pour des enzymes de la synthese de l'acide clavulanique

Country Status (1)

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CA (1) CA2108113C (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9702218D0 (en) * 1997-02-04 1997-03-26 Smithkline Beecham Plc Novel product
ES2131001B1 (es) * 1997-06-16 2000-04-01 Antibioticos Sau Procedimiento para incrementar la produccion de acido clavulanico mediante la expresion de genes reguladores y biosinteticos de streptomyces clavuligerus.
GB9815666D0 (en) 1998-07-17 1998-09-16 Smithkline Beecham Plc Novel compounds
HK1047957A1 (zh) * 1999-09-16 2003-03-14 The Johns-Hopkins University 克拉伏拉尼克酸产量的提高
EP1442123A2 (fr) * 2001-11-07 2004-08-04 Smithkline Beecham Plc Polynucleotides et polypeptides intervenant dans la biosynthese de l'acide clavulinique et leur utilisation
GB0130351D0 (en) * 2001-12-19 2002-02-06 Isis Innovation Cyclisation process
GB0308696D0 (en) 2003-04-15 2003-05-21 Glaxo Group Ltd New process

Also Published As

Publication number Publication date
CA2108113A1 (fr) 1995-04-09

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