CA2108265A1 - Methodes et compositions pour l'isolement de taxanes - Google Patents

Methodes et compositions pour l'isolement de taxanes

Info

Publication number: CA2108265A1
Authority: CA; Canada
Prior art keywords: taxanes; methods; disclosed; compositions; taxol
Prior art date: 1991-04-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA002108265A

Other languages

English (en)

Other versions

CA2108265C (fr

Inventor

Hala N. Eisohly

Edward M. Croom, Jr.

Mahmoud A. Eisohly

James D. Mcchesney

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

University of Mississippi

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-04-19

Filing date

1992-04-14

Publication date

1992-10-20

1992-04-14 Application filed by Individual filed Critical Individual

1992-04-14 Priority claimed from PCT/US1992/003088 external-priority patent/WO1992018492A1/fr

1992-10-20 Publication of CA2108265A1 publication Critical patent/CA2108265A1/fr

2006-12-05 Application granted granted Critical

2006-12-05 Publication of CA2108265C publication Critical patent/CA2108265C/fr

2012-04-14 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

229940123237 Taxane Drugs 0.000 title abstract 6
238000000034 method Methods 0.000 title abstract 4
239000000203 mixture Substances 0.000 title abstract 2
229930012538 Paclitaxel Natural products 0.000 abstract 2
229960001592 paclitaxel Drugs 0.000 abstract 2
RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 2
239000003125 aqueous solvent Substances 0.000 abstract 1
238000004587 chromatography analysis Methods 0.000 abstract 1
238000001035 drying Methods 0.000 abstract 1
238000000605 extraction Methods 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
238000000746 purification Methods 0.000 abstract 1
DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Epoxy Compounds (AREA)
Medicines Containing Plant Substances (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CA002108265A 1991-04-19 1992-04-14 Methodes et compositions pour l'isolement de taxanes Expired - Fee Related CA2108265C (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US69080591A	1991-04-19	1991-04-19
US07/690,805		1991-04-19
PCT/US1992/003088 WO1992018492A1 (fr)	1991-04-19	1992-04-14	Procede et compositions servant a l'isolation de taxanes

Publications (2)

Publication Number	Publication Date
CA2108265A1 true CA2108265A1 (fr)	1992-10-20
CA2108265C CA2108265C (fr)	2006-12-05

Family

ID=37558502

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002108265A Expired - Fee Related CA2108265C (fr)	1991-04-19	1992-04-14	Methodes et compositions pour l'isolement de taxanes

Country Status (1)

Country	Link
CA (1)	CA2108265C (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6878832B2 (en)	2000-11-13	2005-04-12	Lahu Saiji	Isolation of taxanes
WO2007045093A1 (fr) *	2005-10-21	2007-04-26	Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Natural Resources Canada, Canadian Forest Service	Preparation de taxanes

1992
- 1992-04-14 CA CA002108265A patent/CA2108265C/fr not_active Expired - Fee Related

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6878832B2 (en)	2000-11-13	2005-04-12	Lahu Saiji	Isolation of taxanes
WO2007045093A1 (fr) *	2005-10-21	2007-04-26	Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Natural Resources Canada, Canadian Forest Service	Preparation de taxanes

Also Published As

Publication number	Publication date
CA2108265C (fr)	2006-12-05

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Legal Events

Date	Code	Title	Description
1999-03-29	EEER	Examination request
2010-04-14	MKLA	Lapsed