CA2115346A1 - Anticorps chimerique anti-cea - Google Patents
Anticorps chimerique anti-ceaInfo
- Publication number
- CA2115346A1 CA2115346A1 CA002115346A CA2115346A CA2115346A1 CA 2115346 A1 CA2115346 A1 CA 2115346A1 CA 002115346 A CA002115346 A CA 002115346A CA 2115346 A CA2115346 A CA 2115346A CA 2115346 A1 CA2115346 A1 CA 2115346A1
- Authority
- CA
- Canada
- Prior art keywords
- sequence
- seq
- human
- ser
- none
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3007—Carcino-embryonic Antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90407492A | 1992-06-15 | 1992-06-15 | |
| US07/904,074 | 1992-06-15 | ||
| PCT/US1993/005709 WO1993025237A1 (fr) | 1992-06-15 | 1993-06-15 | Anticorps chimerique anti antigene carcino-embryonnaire |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2115346A1 true CA2115346A1 (fr) | 1993-12-23 |
Family
ID=25418496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002115346A Abandoned CA2115346A1 (fr) | 1992-06-15 | 1993-06-15 | Anticorps chimerique anti-cea |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0606430A1 (fr) |
| JP (1) | JPH06509947A (fr) |
| AU (1) | AU4536693A (fr) |
| CA (1) | CA2115346A1 (fr) |
| WO (1) | WO1993025237A1 (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6335160B1 (en) | 1995-02-17 | 2002-01-01 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
| US5837458A (en) | 1994-02-17 | 1998-11-17 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
| US6309883B1 (en) | 1994-02-17 | 2001-10-30 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
| US6165793A (en) * | 1996-03-25 | 2000-12-26 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
| US20060257890A1 (en) * | 1996-05-20 | 2006-11-16 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| US6117679A (en) | 1994-02-17 | 2000-09-12 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
| US6995017B1 (en) | 1994-02-17 | 2006-02-07 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
| US6153410A (en) * | 1997-03-25 | 2000-11-28 | California Institute Of Technology | Recombination of polynucleotide sequences using random or defined primers |
| GB9712512D0 (en) | 1997-06-16 | 1997-08-20 | Bioinvent Int Ab | A method for in vitro molecular evolution of protein function |
| US6537746B2 (en) | 1997-12-08 | 2003-03-25 | Maxygen, Inc. | Method for creating polynucleotide and polypeptide sequences |
| US6958213B2 (en) | 2000-12-12 | 2005-10-25 | Alligator Bioscience Ab | Method for in vitro molecular evolution of protein function |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4921690A (en) * | 1986-12-29 | 1990-05-01 | City Of Hope | Method of enhancing the biodistribution of antibody for localization in lesions |
| US5081235A (en) * | 1989-07-26 | 1992-01-14 | City Of Hope | Chimeric anti-cea antibody |
-
1993
- 1993-06-15 EP EP93915354A patent/EP0606430A1/fr not_active Withdrawn
- 1993-06-15 CA CA002115346A patent/CA2115346A1/fr not_active Abandoned
- 1993-06-15 WO PCT/US1993/005709 patent/WO1993025237A1/fr not_active Ceased
- 1993-06-15 AU AU45366/93A patent/AU4536693A/en not_active Abandoned
- 1993-06-15 JP JP6501788A patent/JPH06509947A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU4536693A (en) | 1994-01-04 |
| JPH06509947A (ja) | 1994-11-10 |
| WO1993025237A1 (fr) | 1993-12-23 |
| EP0606430A1 (fr) | 1994-07-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2070659C (fr) | Preparation d'anticorps | |
| Neumaier et al. | Cloning of the genes for T84. 66, an antibody that has a high specificity and affinity for carcinoembryonic antigen, and expression of chimeric human/mouse T84. 66 genes in myeloma and Chinese hamster ovary cells | |
| US5968509A (en) | Antibodies with binding affinity for the CD3 antigen | |
| AU606320B2 (en) | Modular assembly of antibody genes, antibodies prepared thereby and use | |
| Fell et al. | Homologous recombination in hybridoma cells: heavy chain chimeric antibody produced by gene targeting. | |
| AU629401B2 (en) | Chimeric anti-cea antibody | |
| AU651984B2 (en) | CDR grafted anti-CEA antibodies and their production | |
| AU632462B2 (en) | Modular assembly of antibody genes, antibodies prepared thereby and use | |
| CA2155934A1 (fr) | Nouvelle famille d'anticorps chimeriques diriges contre les antigenes carcinoembryonnaires | |
| GB2276169A (en) | Antibodies specific for carcinoembryonic antigen | |
| ZA200100478B (en) | Hybrid human/rodent igg antibody to cd3, and methods of its construction. | |
| JPH06319548A (ja) | 二特異的融合タンパク質をコードする発現ベクター及び哺乳動物細胞における生物学的に活性な二特異的融合タンパク質の生産方法 | |
| HU215383B (hu) | Humanizált antitest és eljárás előállítására | |
| CA2115346A1 (fr) | Anticorps chimerique anti-cea | |
| US5075431A (en) | Chimeric anti-CEA antibody | |
| US6232123B1 (en) | Monoclonal antibodies against leucocyte-specific G protein-coupled receptors | |
| AU652923B2 (en) | Specific binding agents | |
| US5674994A (en) | Polynucleotides encoding the anti-PEM antibody BW835 variable domains and expression vectors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |