CA2126757A1 - Utilisation de composes trioxolane et diperoxyde en medecine - Google Patents
Utilisation de composes trioxolane et diperoxyde en medecineInfo
- Publication number
- CA2126757A1 CA2126757A1 CA002126757A CA2126757A CA2126757A1 CA 2126757 A1 CA2126757 A1 CA 2126757A1 CA 002126757 A CA002126757 A CA 002126757A CA 2126757 A CA2126757 A CA 2126757A CA 2126757 A1 CA2126757 A1 CA 2126757A1
- Authority
- CA
- Canada
- Prior art keywords
- mammal
- trioxolane
- diperoxide
- unsaturated hydrocarbon
- terpene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 239000001788 mono and diglycerides of fatty acids Substances 0.000 description 1
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- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- MWYYLZRWWNBROW-BDZRSQQBSA-N ophiobolin A Chemical compound C[C@H]1C[C@H](C=C(C)C)O[C@]11[C@@H]2C\C=C(C=O)/[C@@H](C(=O)C[C@@]3(C)O)[C@@H]3C[C@@]2(C)CC1 MWYYLZRWWNBROW-BDZRSQQBSA-N 0.000 description 1
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- ONVABDHFQKWOSV-NDLGOLERSA-N phyllocladene Chemical compound C1C[C@@H](C2)C(=C)C[C@]32CC[C@@H]2C(C)(C)CCC[C@@]2(C)[C@@H]31 ONVABDHFQKWOSV-NDLGOLERSA-N 0.000 description 1
- BOTWFXYSPFMFNR-PYDDKJGSSA-N phytol Chemical compound CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC\C(C)=C\CO BOTWFXYSPFMFNR-PYDDKJGSSA-N 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
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- 239000003755 preservative agent Substances 0.000 description 1
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- 210000004761 scalp Anatomy 0.000 description 1
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- 235000011803 sesame oil Nutrition 0.000 description 1
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- 231100000475 skin irritation Toxicity 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
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- 229940031439 squalene Drugs 0.000 description 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 description 1
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- 239000000516 sunscreening agent Substances 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
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- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 230000036575 thermal burns Effects 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- 206010044008 tonsillitis Diseases 0.000 description 1
- 229940100611 topical cream Drugs 0.000 description 1
- CRDAMVZIKSXKFV-UHFFFAOYSA-N trans-Farnesol Natural products CC(C)=CCCC(C)=CCCC(C)=CCO CRDAMVZIKSXKFV-UHFFFAOYSA-N 0.000 description 1
- XJPBRODHZKDRCB-UHFFFAOYSA-N trans-alpha-ocimene Natural products CC(=C)CCC=C(C)C=C XJPBRODHZKDRCB-UHFFFAOYSA-N 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- UYPYRKYUKCHHIB-UHFFFAOYSA-N trimethylamine N-oxide Chemical class C[N+](C)(C)[O-] UYPYRKYUKCHHIB-UHFFFAOYSA-N 0.000 description 1
- PHYFQTYBJUILEZ-IUPFWZBJSA-N triolein Chemical class CCCCCCCC\C=C/CCCCCCCC(=O)OCC(OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCCCC PHYFQTYBJUILEZ-IUPFWZBJSA-N 0.000 description 1
- 241001148471 unidentified anaerobic bacterium Species 0.000 description 1
- 208000019206 urinary tract infection Diseases 0.000 description 1
- OOTXFYSZXCPMPG-BMYLZFHVSA-N ursane Chemical compound C1CCC(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C)CC[C@@H](C)[C@H](C)[C@H]5[C@H]4CC[C@@H]3[C@]21C OOTXFYSZXCPMPG-BMYLZFHVSA-N 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
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- 230000009278 visceral effect Effects 0.000 description 1
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
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- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Dental Preparations (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81396291A | 1991-12-24 | 1991-12-24 | |
| US07/840,388 US5270344A (en) | 1988-06-24 | 1992-02-24 | Method of treating a systemic disorder using trioxolane and diperoxide compounds |
| US840,388 | 1992-02-24 | ||
| US813,962 | 1992-02-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2126757A1 true CA2126757A1 (fr) | 1993-07-08 |
Family
ID=27123798
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002126757A Abandoned CA2126757A1 (fr) | 1991-12-24 | 1992-12-17 | Utilisation de composes trioxolane et diperoxyde en medecine |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0644716A4 (fr) |
| JP (1) | JPH08502018A (fr) |
| AU (1) | AU3328293A (fr) |
| CA (1) | CA2126757A1 (fr) |
| MX (1) | MX9207493A (fr) |
| WO (1) | WO1993012654A1 (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPN115095A0 (en) * | 1995-02-15 | 1995-03-09 | Butt, Henry Lawrence | Analysis of and compositions and methods for the treatment of disease |
| JP3056730B1 (ja) * | 1999-03-31 | 2000-06-26 | 株式会社バイオ技研 | 二形性真菌であるカンジダ属に対する形態転換制御活性機能剤 |
| EP1750690A1 (fr) * | 2004-05-10 | 2007-02-14 | Robert F. Hofmann | Utilisation d'une formulation therapeutique oxydative ciblee dans le traitement du cancer |
| WO2006002287A1 (fr) * | 2004-06-23 | 2006-01-05 | Hofmann Robert F | Utilisation de preparation therapeutique oxydative ciblee dans un traitement endodontique |
| CN101473009A (zh) * | 2006-06-28 | 2009-07-01 | 株式会社Erc科技 | 臭氧化表面活性剂 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1210949A (en) * | 1914-07-30 | 1917-01-02 | Gen Res Lab | Medicinal compound. |
| US2083572A (en) * | 1928-04-25 | 1937-06-15 | Susan M Mckee | Process of treating oil |
| US2356062A (en) * | 1942-02-03 | 1944-08-15 | Latimer Lab Inc | Therapeutic composition |
| US4591602A (en) * | 1982-04-16 | 1986-05-27 | James H. Brown | Ozonide esters and topical compositions containing same |
| US4451480A (en) * | 1982-04-16 | 1984-05-29 | James Howard Brown | Method of treating acne using ozonized materials |
| US5086076A (en) * | 1988-06-24 | 1992-02-04 | Stephen Herman | Antiviral pharmaceutical compositions comprising a terpene ozonide |
| US4983637A (en) * | 1988-06-24 | 1991-01-08 | Stephen Herman | Method for treating viral infection of HIV |
-
1992
- 1992-12-17 CA CA002126757A patent/CA2126757A1/fr not_active Abandoned
- 1992-12-17 JP JP5511772A patent/JPH08502018A/ja active Pending
- 1992-12-17 EP EP93901179A patent/EP0644716A4/en not_active Withdrawn
- 1992-12-17 AU AU33282/93A patent/AU3328293A/en not_active Abandoned
- 1992-12-17 WO PCT/US1992/010979 patent/WO1993012654A1/fr not_active Ceased
- 1992-12-22 MX MX9207493A patent/MX9207493A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX9207493A (es) | 1994-03-31 |
| AU3328293A (en) | 1993-07-28 |
| EP0644716A1 (fr) | 1995-03-29 |
| EP0644716A4 (en) | 1995-04-19 |
| WO1993012654A1 (fr) | 1993-07-08 |
| JPH08502018A (ja) | 1996-03-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Dead |