CA2139116A1 - 1-aryl (o-alcoxyphenyl-4 piperazinyl-1)-2, -3 ou -4 alcanols, leur procede de preparation et leur utilisation pour la preparation de medicaments - Google Patents

1-aryl (o-alcoxyphenyl-4 piperazinyl-1)-2, -3 ou -4 alcanols, leur procede de preparation et leur utilisation pour la preparation de medicaments

Info

Publication number
CA2139116A1
CA2139116A1 CA002139116A CA2139116A CA2139116A1 CA 2139116 A1 CA2139116 A1 CA 2139116A1 CA 002139116 A CA002139116 A CA 002139116A CA 2139116 A CA2139116 A CA 2139116A CA 2139116 A1 CA2139116 A1 CA 2139116A1
Authority
CA
Canada
Prior art keywords
hydrogen atom
chosen
formula
hydroxy group
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002139116A
Other languages
English (en)
French (fr)
Inventor
Patrick Houziaux
Jean-Pierre Riffaud
Patrick Saur
Bernard Danree
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut de Recherches Chimiques et Biologiques Appliquees SARL IRCEBA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2139116A1 publication Critical patent/CA2139116A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002139116A 1992-06-24 1993-06-24 1-aryl (o-alcoxyphenyl-4 piperazinyl-1)-2, -3 ou -4 alcanols, leur procede de preparation et leur utilisation pour la preparation de medicaments Abandoned CA2139116A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9207750A FR2692894B1 (fr) 1992-06-24 1992-06-24 Aryl-1-(o-alcoxy-phényl-4-pipérazinyl-1)-2, 3- ou 4-alcanols, leur procédé de préparation et leur utilisation pour la préparation de médicaments.
FR92/07750 1992-06-24

Publications (1)

Publication Number Publication Date
CA2139116A1 true CA2139116A1 (fr) 1994-01-06

Family

ID=9431140

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002139116A Abandoned CA2139116A1 (fr) 1992-06-24 1993-06-24 1-aryl (o-alcoxyphenyl-4 piperazinyl-1)-2, -3 ou -4 alcanols, leur procede de preparation et leur utilisation pour la preparation de medicaments

Country Status (5)

Country Link
EP (1) EP0647221A1 (de)
JP (1) JPH07508728A (de)
CA (1) CA2139116A1 (de)
FR (1) FR2692894B1 (de)
WO (1) WO1994000442A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4189867B2 (ja) * 1997-05-12 2008-12-03 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 良性前立腺肥大症の治療で有用なアリール置換ピペラジン類
KR100698400B1 (ko) 2004-04-14 2007-03-23 이은주 탈모증 및 전립선비대증 치료를 위한 약제학적 조성물
AU2005232511B2 (en) * 2004-04-14 2008-07-03 Eun-Joo Lee Pharmaceutical composition for treating hair loss and benign prostatic hyperplasia

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1458905A (fr) * 1959-03-26 1966-04-29 Procédé de préparation de 1-aralcoyl-4-arylpipérazines
US2997474A (en) * 1959-10-12 1961-08-22 Paul A J Janssen 1-aryl-omega-(4-arylpiperazine) alkanols
FR1332560A (fr) * 1961-03-20 1963-07-19 Ciba Geigy Procédé de préparation de diaza-cyclo-alcanes, entre autres de la 1-[3-éthoxy-3-(4-méthyl-phényl)-propyl]-3-méthyl-4-phényl-pipérazine et de ses sels
FR1483416A (fr) * 1965-06-16 1967-06-02 Science Union Et Compagnie Procédé de préparation de nouveaux dérivés du pipérazino-phényléthanol
BE758380A (fr) * 1969-11-04 1971-04-16 Sumitomo Chemical Co Procede de preparation de derives d'aryl-cetones
KR0173310B1 (ko) * 1989-04-22 1999-02-01 폴 에이 리쳐 피페라진 유도체
HU221315B1 (en) * 1989-04-22 2002-09-28 Wyeth John & Brother Ltd Alkyl-substituted piperazine derivatives, pharmaceutical compositions containing them, and process for producing them
GB9021453D0 (en) * 1990-10-03 1990-11-14 Wyeth John & Brother Ltd Piperazine derivatives

Also Published As

Publication number Publication date
WO1994000442A1 (fr) 1994-01-06
FR2692894A1 (fr) 1993-12-31
JPH07508728A (ja) 1995-09-28
EP0647221A1 (de) 1995-04-12
FR2692894B1 (fr) 1994-10-14

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Legal Events

Date Code Title Description
FZDE Dead