CA2155666A1 - Nouveaux derives de l'acide 3-hydroxyanthranilique; methodes et produits intermediaires pour leur preparation; nouvelles compositions pharmaceutiques et leur utilisation - Google Patents

Nouveaux derives de l'acide 3-hydroxyanthranilique; methodes et produits intermediaires pour leur preparation; nouvelles compositions pharmaceutiques et leur utilisation

Info

Publication number: CA2155666A1
Authority: CA; Canada
Prior art keywords: novel; intermediates; preparation; methods; pharmaceutical compositions
Prior art date: 1993-02-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA002155666A

Other languages

English (en)

Other versions

CA2155666C (fr

Inventor

Susanna Karin Maria Bjork

Barry K. Carpenter

Kristina Brigitta Gotthammar

Mat Torbjorn Linderberg

Per Johan Luthman

Kerstin Margareta Irma Persson

Robert Schwarcz

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Cornell Research Foundation Inc

University of Maryland College Park

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-02-26

Filing date

1994-02-24

Publication date

1994-09-01

1993-02-26 Priority claimed from SE9300658A external-priority patent/SE9300658D0/xx

1994-02-24 Application filed by Individual filed Critical Individual

1994-09-01 Publication of CA2155666A1 publication Critical patent/CA2155666A1/fr

2006-04-18 Application granted granted Critical

2006-04-18 Publication of CA2155666C publication Critical patent/CA2155666C/fr

2014-02-24 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

WJXSWCUQABXPFS-UHFFFAOYSA-N 3-hydroxyanthranilic acid Chemical class NC1=C(O)C=CC=C1C(O)=O WJXSWCUQABXPFS-UHFFFAOYSA-N 0.000 title abstract 2
239000000543 intermediate Substances 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
108010072768 3-hydroxyanthranilate 3,4-dioxygenase Proteins 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
102100029016 3-hydroxyanthranilate 3,4-dioxygenase Human genes 0.000 abstract 1
101710138657 Neurotoxin Proteins 0.000 abstract 1
-1 OSO2CH3 Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004414 alkyl thio group Chemical group 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000005110 aryl thio group Chemical group 0.000 abstract 1
125000004104 aryloxy group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
125000003709 fluoroalkyl group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000002581 neurotoxin Substances 0.000 abstract 1
231100000618 neurotoxin Toxicity 0.000 abstract 1
GJAWHXHKYYXBSV-UHFFFAOYSA-N quinolinic acid Chemical compound OC(=O)C1=CC=CN=C1C(O)=O GJAWHXHKYYXBSV-UHFFFAOYSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000002827 triflate group Chemical group FC(S(=O)(=O)O*)(F)F 0.000 abstract 1
125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1

Landscapes

Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

CA002155666A 1993-02-26 1994-02-24 Nouveaux derives de l'acide 3-hydroxyanthranilique; methodes et produits intermediaires pour leur preparation; nouvelles compositions pharmaceutiques et leur utilisation Expired - Lifetime CA2155666C (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
SE9300658-3		1993-02-26
SE9300658A SE9300658D0 (sv)	1993-02-26	1993-02-26	New compounds
PCT/SE1994/000153 WO1994019316A1 (fr)	1993-02-26	1994-02-24	Nouveaux composes

Publications (2)

Publication Number	Publication Date
CA2155666A1 true CA2155666A1 (fr)	1994-09-01
CA2155666C CA2155666C (fr)	2006-04-18

Family

ID=36250860

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002155666A Expired - Lifetime CA2155666C (fr)	1993-02-26	1994-02-24	Nouveaux derives de l'acide 3-hydroxyanthranilique; methodes et produits intermediaires pour leur preparation; nouvelles compositions pharmaceutiques et leur utilisation

Country Status (1)

Country	Link
CA (1)	CA2155666C (fr)

1994
- 1994-02-24 CA CA002155666A patent/CA2155666C/fr not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA2155666C (fr)	2006-04-18

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Legal Events

Date	Code	Title	Description
2001-01-12	EEER	Examination request
2014-04-28	MKEX	Expiry	Effective date: 20140224