CA2180726A1 - Adhesines bacteriennes specifiques de recepteurs et leur utilisation - Google Patents

Adhesines bacteriennes specifiques de recepteurs et leur utilisation

Info

Publication number
CA2180726A1
CA2180726A1 CA 2180726 CA2180726A CA2180726A1 CA 2180726 A1 CA2180726 A1 CA 2180726A1 CA 2180726 CA2180726 CA 2180726 CA 2180726 A CA2180726 A CA 2180726A CA 2180726 A1 CA2180726 A1 CA 2180726A1
Authority
CA
Canada
Prior art keywords
adhesin
thr
gly
ser
val
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2180726
Other languages
English (en)
Inventor
Evgeni Veniaminovic Sokurenko
David Long Hasty
Per Klemm
Lars Pallesen
Sýren Molin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
GX BioSystems AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GX BioSystems AS filed Critical GX BioSystems AS
Publication of CA2180726A1 publication Critical patent/CA2180726A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne des adhésines bactériennes sélectionnées ou recombinées pour présenter la capacité de se fixer spécifiquement à des récepteurs inanimés ou animés prédéterminés et sélectionnés. L'invention concerne également l'utilisation de telles adhésines ou de bactéries exprimant ces adhésines pour cibler des composés et/ou des bactéries utiles à des cellules et des surfaces sélectionnées.
CA 2180726 1994-01-27 1995-01-27 Adhesines bacteriennes specifiques de recepteurs et leur utilisation Abandoned CA2180726A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18716694A 1994-01-27 1994-01-27
US08/187,166 1994-01-27

Publications (1)

Publication Number Publication Date
CA2180726A1 true CA2180726A1 (fr) 1995-08-03

Family

ID=22687857

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2180726 Abandoned CA2180726A1 (fr) 1994-01-27 1995-01-27 Adhesines bacteriennes specifiques de recepteurs et leur utilisation

Country Status (4)

Country Link
EP (1) EP0738325A1 (fr)
AU (1) AU1532795A (fr)
CA (1) CA2180726A1 (fr)
WO (1) WO1995020657A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2252438C (fr) * 1996-04-19 2011-03-29 Henry M. Jackson Foundation For The Advancement Of Military Medicine Intimine marquee a l'histidine et procedes d'utilisation de l'intimine pour stimuler une reaction immunitaire et en tant que porteur d'antigene a capacite de ciblage
WO1999057276A1 (fr) * 1998-04-30 1999-11-11 Gyre Ltd. Proteines d'adhesine multifonctionnelles et affichage de ces proteines dans des cellules microbiennes
GB9819484D0 (en) * 1998-09-07 1998-10-28 Univ Bristol Therapeutic agents
DE19850718C1 (de) * 1998-11-03 2000-05-18 Hildt Eberhardt Zellpermeabilität-vermittelndes Polypeptid
EP1194563A1 (fr) * 1999-07-15 2002-04-10 Medimmune, Inc. Vaccins a base d'adhesine fimh
AU2001271907A1 (en) * 2000-07-07 2002-01-21 Medimmune, Inc. FimH adhesin proteins and methods of use
WO2002059156A2 (fr) 2000-12-22 2002-08-01 Medimmune, Inc. Composes therapeutiques lies structuralement a des polypeptides bacteriens
US20040067544A1 (en) * 2002-06-27 2004-04-08 Viola Vogel Use of adhesion molecules as bond stress-enhanced nanoscale binding switches
EP2897638A1 (fr) 2012-09-24 2015-07-29 Montana State University-Bozeman Lactococcus lactis recombinant exprimant l'antigène 1 du facteur de colonisation d'escherichia coli (cfa/i) de type pilus et procédés d'utilisation correspondants
BR112022014555A2 (pt) 2020-02-23 2022-09-20 Pfizer Composições de escherichia coli e métodos das mesmas.
PE20231934A1 (es) * 2020-10-27 2023-12-01 Pfizer Composiciones de escherichia coli y metodos de las mismas
US12138302B2 (en) 2020-10-27 2024-11-12 Pfizer Inc. Escherichia coli compositions and methods thereof
US12357681B2 (en) 2020-12-23 2025-07-15 Pfizer Inc. E. coli FimH mutants and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990000614A1 (fr) * 1988-07-13 1990-01-25 Baylor College Of Medicine Proteines specifiques de recepteurs et utilisation de telles proteines dans l'identification du type de recepteur
US5202113A (en) * 1990-04-30 1993-04-13 The United States Of America As Represented By The Department Of Health And Human Services Plaque-inhibiting protein from bacteroides loeschei and methods for using the same
ZA934199B (en) * 1992-06-18 1994-01-10 Akzo Nv Carrier system against gnrh

Also Published As

Publication number Publication date
AU1532795A (en) 1995-08-15
EP0738325A1 (fr) 1996-10-23
WO1995020657A1 (fr) 1995-08-03

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