CA2181351C - Process and intermediates for preparing naphthyridonecarboxylic acid salts - Google Patents

Process and intermediates for preparing naphthyridonecarboxylic acid salts

Info

Publication number: CA2181351C
Authority: CA; Canada
Prior art keywords: formula; compound; acid; alkyl; treating
Prior art date: 1994-01-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

CA002181351A

Other languages

English (en)

French (fr)

Other versions

CA2181351A1 (en

Inventor

Tamim F. Braish

Darrell E. Fox

Timothy Norris

Peter R. Rose

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Inc

Original Assignee

Pfizer Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-01-18

Filing date

1994-12-12

Publication date

1999-09-28

1994-12-12 Application filed by Pfizer Inc filed Critical Pfizer Inc

1995-07-20 Publication of CA2181351A1 publication Critical patent/CA2181351A1/en

1999-09-28 Application granted granted Critical

1999-09-28 Publication of CA2181351C publication Critical patent/CA2181351C/en

2014-12-12 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

CA002181351A 1994-01-18 1994-12-12 Process and intermediates for preparing naphthyridonecarboxylic acid salts Expired - Fee Related CA2181351C (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US18194294A	1994-01-18	1994-01-18
US08/181,942		1994-01-18
PCT/IB1994/000410 WO1995019361A1 (en)	1994-01-18	1994-12-12	Process and intermediates for preparing naphthyridonecarboxylic acid salts

Publications (2)

Publication Number	Publication Date
CA2181351A1 CA2181351A1 (en)	1995-07-20
CA2181351C true CA2181351C (en)	1999-09-28

Family

ID=22666458

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002181351A Expired - Fee Related CA2181351C (en)	1994-01-18	1994-12-12	Process and intermediates for preparing naphthyridonecarboxylic acid salts

Country Status (19)

Country	Link
EP (1)	EP0740667A1 (pl)
JP (1)	JP2891543B2 (pl)
KR (1)	KR100221386B1 (pl)
CN (1)	CN1141634A (pl)
AU (1)	AU694149B2 (pl)
BR (1)	BR9408490A (pl)
CA (1)	CA2181351C (pl)
CZ (1)	CZ286896B6 (pl)
FI (1)	FI962880A0 (pl)
HU (1)	HUT74883A (pl)
IL (1)	IL112323A (pl)
MY (1)	MY130510A (pl)
NO (1)	NO305838B1 (pl)
NZ (1)	NZ276478A (pl)
PL (1)	PL179996B1 (pl)
RU (1)	RU2147303C1 (pl)
TW (1)	TW414791B (pl)
WO (1)	WO1995019361A1 (pl)
ZA (1)	ZA95340B (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5763454A (en) *	1995-06-06	1998-06-09	Pfizer, Inc.	Crystal form of anhydrous 7-( 1α,5α,6α!-6-amino-3-azabicyclo 3.1.0!hex-3-yl)-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1,8 naphthyridine-3-carboxylic acid, methanessulfonic acid salt
ES2095809B1 (es) *	1995-07-27	1997-12-16	Sint Quimica Sa	Procedimiento para la preparacion de acidos naftiridin carboxilicos y sus sales.
GB9524466D0 (en) *	1995-11-30	1996-01-31	Pfizer Ltd	Process
JPH1087617A (ja) *	1996-07-09	1998-04-07	Pfizer Inc	キノリン系抗生物質の合成に有用な中間体の製法
GB9614422D0 (en) *	1996-07-09	1996-09-04	Pfizer Ltd	Novel process
HN1998000106A (es)	1997-08-01	1999-01-08	Pfizer Prod Inc	Composiciones parenterales de alatroflaxacino
US6114531A (en) *	1998-07-28	2000-09-05	Pfizer Inc.	Process for preparing quinolone and naphthyridone carboxylic acids
HN1999000141A (es) *	1998-09-03	2000-06-19	Pfizer Prod Inc	Procedimiento para preparar sales de trovafloxacina de adicion de acidos.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5164402A (en) *	1989-08-16	1992-11-17	Pfizer Inc	Azabicyclo quinolone and naphthyridinone carboxylic acids
US5256791A (en)	1992-03-02	1993-10-26	Pfizer Inc.	Preparation of intermediates in the synthesis of quinoline antibiotics

1994
- 1994-12-12 CZ CZ19962111A patent/CZ286896B6/cs not_active IP Right Cessation
- 1994-12-12 BR BR9408490A patent/BR9408490A/pt not_active Application Discontinuation
- 1994-12-12 RU RU96115919A patent/RU2147303C1/ru active
- 1994-12-12 AU AU10754/95A patent/AU694149B2/en not_active Ceased
- 1994-12-12 EP EP95901569A patent/EP0740667A1/en not_active Withdrawn
- 1994-12-12 NZ NZ276478A patent/NZ276478A/en unknown
- 1994-12-12 KR KR1019960703846A patent/KR100221386B1/ko not_active Expired - Fee Related
- 1994-12-12 CN CN94194842A patent/CN1141634A/zh active Pending
- 1994-12-12 HU HU9601957A patent/HUT74883A/hu unknown
- 1994-12-12 PL PL94317043A patent/PL179996B1/pl unknown
- 1994-12-12 WO PCT/IB1994/000410 patent/WO1995019361A1/en not_active Ceased
- 1994-12-12 CA CA002181351A patent/CA2181351C/en not_active Expired - Fee Related
- 1994-12-12 JP JP7518931A patent/JP2891543B2/ja not_active Expired - Lifetime
- 1994-12-17 TW TW083111804A patent/TW414791B/zh not_active IP Right Cessation
1995
- 1995-01-12 IL IL11232395A patent/IL112323A/en not_active IP Right Cessation
- 1995-01-17 MY MYPI95000103A patent/MY130510A/en unknown
- 1995-01-17 ZA ZA95340A patent/ZA95340B/xx unknown
1996
- 1996-07-17 NO NO962990A patent/NO305838B1/no not_active IP Right Cessation
- 1996-07-17 FI FI962880A patent/FI962880A0/fi unknown

Also Published As

Publication number	Publication date
NO305838B1 (no)	1999-08-02
EP0740667A1 (en)	1996-11-06
CZ286896B6 (en)	2000-07-12
AU694149B2 (en)	1998-07-16
ZA95340B (en)	1996-07-17
AU1075495A (en)	1995-08-01
HU9601957D0 (en)	1996-09-30
BR9408490A (pt)	1997-08-26
IL112323A0 (en)	1995-03-30
RU2147303C1 (ru)	2000-04-10
MY130510A (en)	2007-06-29
IL112323A (en)	2001-03-19
TW414791B (en)	2000-12-11
FI962880A7 (fi)	1996-07-17
HUT74883A (en)	1997-02-28
KR100221386B1 (ko)	1999-09-15
CN1141634A (zh)	1997-01-29
PL179996B1 (en)	2000-11-30
WO1995019361A1 (en)	1995-07-20
JPH09501182A (ja)	1997-02-04
CA2181351A1 (en)	1995-07-20
NO962990D0 (no)	1996-07-17
CZ211196A3 (en)	1997-01-15
NZ276478A (en)	1998-05-27
NO962990L (no)	1996-07-17
JP2891543B2 (ja)	1999-05-17
PL317043A1 (en)	1997-03-03
FI962880A0 (fi)	1996-07-17

Legal Events

Date	Code	Title	Description
1996-07-16	EEER	Examination request
2002-12-12	MKLA	Lapsed

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Hubschwerlen et al.	1992	Pyrimido [1, 6-a] benzimidazoles: a new class of DNA gyrase inhibitors
US4929614A (en)	1990-05-29	Benzodiazepines, process and intermediates for the preparation thereof and their application in therapy
US6184380B1 (en)	2001-02-06	Process for preparing naphthyridones and intermediates
EP0297858A2 (en)	1989-01-04	Bridged-diazabicycloalkyl quinolone carboxylic acids and esters
CA2181351C (en)	1999-09-28	Process and intermediates for preparing naphthyridonecarboxylic acid salts
US20050070548A1 (en)	2005-03-31	Hexa-and octahydro-pyrido[1,2-a]pyrazine derivatives with NK1 antagonistic activity
RU2049778C1 (ru)	1995-12-10	Способ получения производного 8-хлорхинолона
CA2305342A1 (en)	1999-04-15	Novel heterocyclic derivatives useful in treating central nervous system disorders
US5929240A (en)	1999-07-27	Process and intermediates for preparing naphthyridonecarboxylic acid salts
KR100236818B1 (ko)	2000-03-15	나프티리돈카복실산 염의 중간체 및 그의 제조방법
EP0930297B1 (en)	2003-04-23	A process for preparing naphthyridones and intermediates
AU703541B2 (en)	1999-03-25	An intermediate for preparing naphthyridonecarboxylic acid salts
US7019142B2 (en)	2006-03-28	Process for preparing naphthyridones and intermediates
CA2281244C (en)	2003-05-20	Process for preparing trovafloxacin acid salts
RU2314296C2 (ru)	2008-01-10	Способ получения имидазолильных соединений
CN103012198A (zh)	2013-04-03	光学活性环状化合物的制备方法
MXPA99008100A (en)	2000-06-05	Procedure for preparing aci additional trovafloxacin salts
CZ11999A3 (cs)	2000-02-16	Způsob výroby naftyridonů a meziprodukty