CA2185568C - Vaccins contre les infections a chlamydiae et leur procede - Google Patents

Vaccins contre les infections a chlamydiae et leur procede Download PDF

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Publication number
CA2185568C
CA2185568C CA002185568A CA2185568A CA2185568C CA 2185568 C CA2185568 C CA 2185568C CA 002185568 A CA002185568 A CA 002185568A CA 2185568 A CA2185568 A CA 2185568A CA 2185568 C CA2185568 C CA 2185568C
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CA
Canada
Prior art keywords
glxa
monoclonal
igg
antibody
vaccine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002185568A
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English (en)
Other versions
CA2185568A1 (fr
Inventor
Alex Bruce Macdonald
Judith A. Whittum-Hudson
William Mark Saltzman
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Individual
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Individual
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Publication date
Application filed by Individual filed Critical Individual
Publication of CA2185568A1 publication Critical patent/CA2185568A1/fr
Application granted granted Critical
Publication of CA2185568C publication Critical patent/CA2185568C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4233—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-bacterial Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne un vaccin administré par voie orale ou par injection, qui est spécifique du gendre Chlamydia. Ce vaccin contient un anticorps anti-idiotype ou le fragment Fab de celui-ci enfermé dans des microsphères formées par un polymère acceptable sur le plan pharmacologique et il est capable de produire chez un animal une réponse immunitaire avec production d'un anticorps anti-anti-idiotype (anticorps sérique, anticorps sécrétoire ou réponse de lymphocytes T) qui reconnaît un exoantigène glycolipidique (GLXA) des Chlamydiae. Le vaccin administré par voie orale ou par injection est produit à partir d'un anticorps idiotype vis-à-vis du GLXA, qui, à son tour, est utilisé pour produire un anticorps anti-idiotype.
CA002185568A 1994-03-16 1995-02-28 Vaccins contre les infections a chlamydiae et leur procede Expired - Fee Related CA2185568C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21386394A 1994-03-16 1994-03-16
US08/213,863 1994-03-16
PCT/US1995/002459 WO1995024922A1 (fr) 1994-03-16 1995-02-28 Vaccins contre les infections a chlamydiae et leur procede

Publications (2)

Publication Number Publication Date
CA2185568A1 CA2185568A1 (fr) 1995-09-21
CA2185568C true CA2185568C (fr) 2001-07-03

Family

ID=22796809

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002185568A Expired - Fee Related CA2185568C (fr) 1994-03-16 1995-02-28 Vaccins contre les infections a chlamydiae et leur procede

Country Status (2)

Country Link
CA (1) CA2185568C (fr)
WO (1) WO1995024922A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8637040B2 (en) 2008-09-21 2014-01-28 National Institute of Health (NIH), U.S. Dept. of Health and Human Services (DHHS) Genus-wide chlamydial peptide vaccine antigens

Also Published As

Publication number Publication date
WO1995024922A1 (fr) 1995-09-21
CA2185568A1 (fr) 1995-09-21

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Legal Events

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