CA2186873A1 - Peptides haptines et leurs utilisations - Google Patents

Peptides haptines et leurs utilisations

Info

Publication number
CA2186873A1
CA2186873A1 CA 2186873 CA2186873A CA2186873A1 CA 2186873 A1 CA2186873 A1 CA 2186873A1 CA 2186873 CA2186873 CA 2186873 CA 2186873 A CA2186873 A CA 2186873A CA 2186873 A1 CA2186873 A1 CA 2186873A1
Authority
CA
Canada
Prior art keywords
seq
peptide
ala
pdc
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2186873
Other languages
English (en)
Inventor
Charles J. Hackett
Julia L. Greenstein
Malcolm L. Gefter
Kurt Jeff Wilson
Cohava Gelber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Immulogic Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immulogic Pharmaceutical Corp filed Critical Immulogic Pharmaceutical Corp
Publication of CA2186873A1 publication Critical patent/CA2186873A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/605—MHC molecules or ligands thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne des peptides transporteurs se liant à l'antigène MHC, ces peptides présentant des liaisons avec des dérivés de la catéchine et étant reconnus par les lymphocytes T spécifiques de l'urushiol. Les composés sont utilisables pour les compositions et procédés thérapeutiques de désensibilisation des individus contre les sensibilisations par contacts avec l'haptine, tels que le sumac vénéneux ou le chêne vénéneux.
CA 2186873 1994-04-01 1995-03-30 Peptides haptines et leurs utilisations Abandoned CA2186873A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US22220694A 1994-04-01 1994-04-01
US08/222,206 1994-04-01
US38364595A 1995-02-06 1995-02-06
US08/383,645 1995-02-06

Publications (1)

Publication Number Publication Date
CA2186873A1 true CA2186873A1 (fr) 1995-10-12

Family

ID=26916551

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2186873 Abandoned CA2186873A1 (fr) 1994-04-01 1995-03-30 Peptides haptines et leurs utilisations

Country Status (3)

Country Link
AU (1) AU2238395A (fr)
CA (1) CA2186873A1 (fr)
WO (1) WO1995026980A2 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2210812C (fr) * 1995-01-16 2009-09-01 Nicholas Manolios Nouveau peptide
GB9702377D0 (en) * 1996-02-23 1997-03-26 Zeneca Ltd Peptide derivatives
WO1997035193A1 (fr) 1996-03-21 1997-09-25 Imperial College Of Science, Technology And Medicine Peptides cryptiques et leur procede d'identification
KR100451522B1 (ko) 1996-06-07 2004-12-08 아스트라제네카 유케이 리미티드 펩티드유도체
CA2257973C (fr) * 1996-06-11 2010-02-02 Northern Sydney Area Health Services Peptides recepteurs d'antigene des cellules t
GB9621836D0 (en) 1996-10-19 1996-12-11 Zeneca Ltd Peptide compounds
GB9624562D0 (en) 1996-11-27 1997-01-15 Zeneca Ltd Peptide derivatives
EP1044019A1 (fr) * 1998-01-09 2000-10-18 Circassia Limited Procedes et compositions de desensibilisation
CA2336238A1 (fr) 1998-07-23 2000-02-03 The President And Fellows Of Harvard College Peptides synthetiques et procedes d'utilisation de ceux-ci dans des therapies de maladies auto-immunes
CA2337688C (fr) 1998-07-23 2016-04-05 Yeda Research And Development Co., Ltd. Traitement de maladies auto-immunes a l'aide du copolymere 1 et copolymeres associes
ES2527760T3 (es) 1998-07-23 2015-01-29 Yeda Research And Development Co., Ltd. Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos
US6800287B2 (en) 1998-09-25 2004-10-05 Yeda Research And Development Co., Ltd. Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
AU775073C (en) * 1998-11-12 2007-05-03 Yeda Research And Development Co. Ltd. Pharmaceutical compositions comprising synthetic peptide copolymers and methods for preventing and treating GVHD and HVGD
US7053043B1 (en) 1999-07-23 2006-05-30 Yeda Research And Development Co.Ltd. Pharmaceutical compositions comprising synthetic peptide copolymers and methods for preventing and treating GVHD and HVGD
ZA200206457B (en) 2000-02-18 2003-08-13 Yeda Res & Dev Oral, nasal and pulmonary dosage formulations of copolymer 1.
US20020077278A1 (en) 2000-06-05 2002-06-20 Yong V. Wee Use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders
WO2002076503A1 (fr) 2000-06-20 2002-10-03 Mayo Foundation For Medical Education And Research Traitement de maladies du systeme nerveux central au moyen d'anticorps diriges contre l'acetate de glatiramere
NZ533327A (en) 2001-12-04 2006-11-30 Teva Pharma Processes for the measurement of the potency of glatiramer acetate
EP1453539B1 (fr) * 2001-12-05 2008-11-19 Circassia Limited Procedes et systemes immunotherapeutiques
GB2440529B (en) * 2006-08-03 2009-05-13 Proimmune Ltd MHC Oligomer, Components Therof, And Methods Of Making The Same
CN110801013B (zh) * 2019-11-19 2023-03-31 西北农林科技大学 一种生物化学法制备非过敏生漆或漆酚的方法及其产品

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4428965A (en) * 1979-05-31 1984-01-31 The University Of Mississippi Tolerizing and desensitizing compounds, compositions and methods of treatment against dermatological conditions caused by allergens from plants and trees of the Anacardiaceae and Ginkgoaceae families
WO1992007952A1 (fr) * 1990-10-30 1992-05-14 Immulogic Pharmaceutical Corporation Methodes de dosage faisant appel a une liaison competitive entre un peptide et des antigenes de complexe majeur d'histocompatibilite
WO1992011859A1 (fr) * 1991-01-08 1992-07-23 Immulogic Pharmaceutical Corporation Hyposensibilisation induite par un peptide de la reponse des lymphocytes t humains a des dermatophagoides (dermatophagoides pteronyssimus)

Also Published As

Publication number Publication date
AU2238395A (en) 1995-10-23
WO1995026980A2 (fr) 1995-10-12
WO1995026980A3 (fr) 1995-12-07

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Legal Events

Date Code Title Description
FZDE Dead