CA2188812A1 - New methods and compounds for the selective modulation of antigen-specific t-cell responsiveness - Google Patents

New methods and compounds for the selective modulation of antigen-specific t-cell responsiveness

Info

Publication number
CA2188812A1
CA2188812A1 CA002188812A CA2188812A CA2188812A1 CA 2188812 A1 CA2188812 A1 CA 2188812A1 CA 002188812 A CA002188812 A CA 002188812A CA 2188812 A CA2188812 A CA 2188812A CA 2188812 A1 CA2188812 A1 CA 2188812A1
Authority
CA
Canada
Prior art keywords
rii
bridging
gamma
cells
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002188812A
Other languages
English (en)
French (fr)
Inventor
Mark De Boer
Serge Barcy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujirebio Europe NV SA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2188812A1 publication Critical patent/CA2188812A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002188812A 1994-05-26 1995-05-26 New methods and compounds for the selective modulation of antigen-specific t-cell responsiveness Abandoned CA2188812A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94870088 1994-05-26
EP94870088.5 1994-05-26

Publications (1)

Publication Number Publication Date
CA2188812A1 true CA2188812A1 (en) 1995-12-07

Family

ID=8218641

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002188812A Abandoned CA2188812A1 (en) 1994-05-26 1995-05-26 New methods and compounds for the selective modulation of antigen-specific t-cell responsiveness

Country Status (4)

Country Link
EP (1) EP0759782A1 (de)
AU (1) AU2670995A (de)
CA (1) CA2188812A1 (de)
WO (1) WO1995032734A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08333262A (ja) * 1995-04-07 1996-12-17 Chugai Pharmaceut Co Ltd 免疫抑制剤
GB9516760D0 (en) * 1995-08-16 1995-10-18 Sandoz Ltd Organic compounds
US7235653B2 (en) 1996-12-31 2007-06-26 Isis Pharmaceuticals, Inc. Oligonucleotide compositions and methods for the modulation of the expression of B7 protein
US6077833A (en) * 1996-12-31 2000-06-20 Isis Pharmaceuticals, Inc. Oligonucleotide compositions and methods for the modulation of the expression of B7 protein
US6319906B1 (en) 1996-12-31 2001-11-20 Isis Pharmaceuticals Oligonucleotide compositions and methods for the modulation of the expression of B7 protein
EP1046651A1 (de) 1999-04-19 2000-10-25 Koninklijke Universiteit Nijmegen Zusammensetzungen und Verfahren zur Modulierung des interaktion zwischen dendritischer und T-zellen
AU8026800A (en) * 1999-10-15 2001-04-30 Baylor Research Institute Use of allogeneic cell lines to load antigen-presenting cells to elicit or eliminate immune responses
EP1118331A1 (de) * 2000-01-21 2001-07-25 I.D.M. Immuno-Designed Molecules Verfahren zur Verstärkung der Präsentation exogener Antigene durch menschlische Antigen-präsentierende Zellen und opsonisierte Mikropartikelkomplexe zur Anwendung dieser Methode
AU2003206264A1 (en) * 2002-02-07 2003-09-02 Vereniging Voor Christelijk Wetenschappelijk Onderwijs MODULATING TOLERANCE BY MODULATING FcGammaRIIB RECEPTOR SIGNALLING
GB0212701D0 (en) * 2002-05-31 2002-07-10 Imp College Innovations Ltd Immunoliposomes
US7691591B2 (en) 2002-09-20 2010-04-06 Stichting Katholieke Universiteit Methods of identifying and isolating cells expressing DC-sign
AU2003269389A1 (en) 2002-09-20 2004-04-08 Stichting Katholieke Universiteit Antigen uptake receptor for candida albicans on dendritic cells
EP1462111A1 (de) * 2003-03-28 2004-09-29 Universiteit Utrecht Holding B.V. Zubereitung zur Induktion von Immuntoleranz
US20040219143A1 (en) * 2003-04-30 2004-11-04 Bluth Martin Heath Methods for recombinant immunoglobulin treatment
US7960355B2 (en) 2003-05-23 2011-06-14 Isis Pharmaceuticals, Inc. Compositions and methods for the modulation of the expression of B7 protein
US7897582B2 (en) 2003-05-23 2011-03-01 Isis Pharmaceuticals, Inc. Oligonucleotide compositions and methods for the modulation of the expression of B7 protein
WO2005058244A2 (en) 2003-12-15 2005-06-30 Alexion Pharmaceuticals, Inc. Novel anti-dc-sign antibodies

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4579840A (en) * 1983-08-12 1986-04-01 Immunetech Pharmaceuticals Method of blocking immune complex binding to immunoglobulin Fc receptors
DE3711724A1 (de) * 1987-04-07 1988-10-20 Harro Boerner Medizinische Kom System zum einwirken auf, insbesondere zerstoeren von viren
GB9009106D0 (en) * 1990-04-23 1990-06-20 3I Res Expl Ltd Processes and intermediates for synthetic antibody derivatives
US5641875A (en) * 1993-09-30 1997-06-24 University Of Pennsylvania DNA encoding chimeric IgG Fc receptor

Also Published As

Publication number Publication date
EP0759782A1 (de) 1997-03-05
AU2670995A (en) 1995-12-21
WO1995032734A1 (en) 1995-12-07

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Legal Events

Date Code Title Description
FZDE Discontinued