CA2188931C - Remede pour le coeur droit - Google Patents

Remede pour le coeur droit Download PDF

Info

Publication number
CA2188931C
CA2188931C CA002188931A CA2188931A CA2188931C CA 2188931 C CA2188931 C CA 2188931C CA 002188931 A CA002188931 A CA 002188931A CA 2188931 A CA2188931 A CA 2188931A CA 2188931 C CA2188931 C CA 2188931C
Authority
CA
Canada
Prior art keywords
cor pulmonale
group
pharmacologically acceptable
agent
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002188931A
Other languages
English (en)
Other versions
CA2188931A1 (fr
Inventor
Reiji Kasukawa
Masayuki Miyata
Yuji Ueno
Hiroshi Koike
Hajimu Kurumatani
Shintaro Nishio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toray Industries Inc
Original Assignee
Toray Industries Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries Inc filed Critical Toray Industries Inc
Publication of CA2188931A1 publication Critical patent/CA2188931A1/fr
Application granted granted Critical
Publication of CA2188931C publication Critical patent/CA2188931C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A61K31/5585Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes having five-membered rings containing oxygen as the only ring hetero atom, e.g. prostacyclin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Seasonings (AREA)
  • Furan Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Un remède pour le coeur droit contient le dérivé de prostaglandine représenté par la formule structurale (A) ou bien un sel pharmacologiquement acceptable de celui-ci, en tant que principe actif, et présente une excellente efficacité administré par voie orale ou parentérale.
CA002188931A 1995-02-27 1996-02-27 Remede pour le coeur droit Expired - Fee Related CA2188931C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP7-38169 1995-02-27
JP3816995 1995-02-27
PCT/JP1996/000443 WO1996026721A1 (fr) 1995-02-27 1996-02-27 Remede pour le c×ur droit

Publications (2)

Publication Number Publication Date
CA2188931A1 CA2188931A1 (fr) 1996-09-06
CA2188931C true CA2188931C (fr) 2007-09-11

Family

ID=12517905

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002188931A Expired - Fee Related CA2188931C (fr) 1995-02-27 1996-02-27 Remede pour le coeur droit

Country Status (13)

Country Link
US (1) US6046233A (fr)
EP (1) EP0759297B1 (fr)
JP (1) JP4062743B2 (fr)
CN (1) CN1127336C (fr)
AT (1) ATE316788T1 (fr)
AU (1) AU4732096A (fr)
CA (1) CA2188931C (fr)
DE (1) DE69635775T2 (fr)
ES (1) ES2252751T3 (fr)
FI (1) FI964303A0 (fr)
NO (1) NO315496B1 (fr)
TW (1) TW419374B (fr)
WO (1) WO1996026721A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000065039A (ko) * 1997-02-27 2000-11-06 히라이 가쯔히꼬 폐순환 개선제
US20100048693A1 (en) * 2006-12-04 2010-02-25 The Regents Of The University Of Colorado, A Body Corporate Treatment of COPD
CN104761509A (zh) 2008-02-28 2015-07-08 日本新药株式会社 纤维化抑制剂
MX2011005482A (es) * 2008-12-05 2011-06-16 Intermed Discovery Gmbh Inhibidores de acumulacion de la proteina del factor 1 inducible por hipoxia.
ES2730410T3 (es) 2012-09-21 2019-11-11 Univ Osaka Material para el tratamiento de insuficiencia cardíaca avanzada como dispositivo de regeneración miocárdica/cardiovascular
EP2913047B1 (fr) 2012-10-29 2019-05-08 Cardio Incorporated Agent thérapeutique spécifique de maladie pulmonaire
US9968716B2 (en) 2013-10-15 2018-05-15 Ono Pharmaceutical Co., Ltd. Drug-eluting stent graft

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58124778A (ja) * 1982-01-20 1983-07-25 Toray Ind Inc 5,6,7−トリノル−4,8−インタ−m−フエニレンPGI↓2誘導体
GB8824187D0 (en) * 1988-10-14 1988-11-23 Wellcome Found Compounds for use in medicine
GB8814438D0 (en) * 1988-06-17 1988-07-20 Wellcome Found Compounds for use in medicine
KR0158870B1 (ko) * 1988-06-17 1998-12-01 마틴 에이. 로쓰블랫 폐순환 승압의 치료, 예방 또는 진단용 조성물
US5496850A (en) * 1991-04-11 1996-03-05 Toray Industries, Inc. Antimetastasis agent of malignant tumors
EP0583482B1 (fr) * 1992-02-07 1999-12-29 Kaken Pharmaceutical Co., Ltd. Remede destine aux blessures ou aux hemorroides
JP3102141B2 (ja) * 1992-05-29 2000-10-23 東レ株式会社 養毛育毛剤
DE69534075T2 (de) * 1994-06-07 2005-07-21 Chugai Seiyaku K.K. Vorbeugungs- und heilmittel für erkrankungen, die durch fibrin- oder thrombusbildung hervorgerufen werden

Also Published As

Publication number Publication date
EP0759297B1 (fr) 2006-02-01
EP0759297A4 (fr) 2003-11-12
FI964303L (fi) 1996-10-25
JP4062743B2 (ja) 2008-03-19
WO1996026721A1 (fr) 1996-09-06
AU4732096A (en) 1996-09-18
DE69635775D1 (de) 2006-04-13
NO315496B1 (no) 2003-09-15
FI964303A7 (fi) 1996-10-25
EP0759297A1 (fr) 1997-02-26
DE69635775T2 (de) 2006-08-10
NO964497D0 (no) 1996-10-23
CA2188931A1 (fr) 1996-09-06
ES2252751T3 (es) 2006-05-16
NO964497L (no) 1996-10-23
TW419374B (en) 2001-01-21
FI964303A0 (fi) 1996-10-25
US6046233A (en) 2000-04-04
ATE316788T1 (de) 2006-02-15
CN1147765A (zh) 1997-04-16
CN1127336C (zh) 2003-11-12

Similar Documents

Publication Publication Date Title
Piper et al. Stimulation of arachidonic acid metabolism and generation of thromboxane A2 by leukotrienes B4, C4 and D4 in guinea-pig lung in vitro
US5006526A (en) Method of treating a vertebrate animal to reduce plasma triglycerides and cholesterol levels and to alleviate and prevent atherosclerosis
HU199302B (en) Process for producing synergic pharmaceutical compositions having hypotensive activity
GB2113524A (en) Elemental diets for liver diseases
CA2188931C (fr) Remede pour le coeur droit
JP2002537258A5 (fr)
GB2170707A (en) An immuno-regulator
JPH0227970B2 (fr)
US4389415A (en) Method of treating hypertension
EP0425909A2 (fr) Méthode pour restaurer l'activité vasorelaxante des artères coronaires, amoindrie par l'athérosclérose ou l'hypercholestérolémie, en utilisant un inhibiteur de l'ACE
AU735975B2 (en) Remedy for pulmonary heart
RU2151597C1 (ru) Способ ингибирования пролиферации кератиноцитов
JPWO1996026721A1 (ja) 肺性心治療剤
US4086354A (en) Novel anti-hypertensive compositions
US3755599A (en) Methods for relieving bronchospasm with prostaglandin a compounds
JPH03118334A (ja) 肝障害抑制剤
JPWO1993005778A1 (ja) 血中脂質代謝改善剤
IL101708A (en) Anti-fattening drugs comprising amino acid derivatives
KR100457499B1 (ko) 폐성심질환치료제
JPS58164507A (ja) ジベンゾシクロヘプテニリデン類による免疫変化剤
JPH07126161A (ja) 心不全治療剤
JP2007238622A (ja) 肺性心治療剤
US4555510A (en) Therapeutic agent for hypertension
US3968145A (en) Methyl 2(1 chloronaphth-2-yloxy)propionate
EP0003353A1 (fr) Composition pharmaceutique pour administration par voie orale pour le traitement de l'hypertension

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed