CA2190732C - Procede et appareil pour recueillir, conserver et analyser en temps reelle sang ou un autre fluide du corps - Google Patents

Procede et appareil pour recueillir, conserver et analyser en temps reelle sang ou un autre fluide du corps Download PDF

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Publication number
CA2190732C
CA2190732C CA002190732A CA2190732A CA2190732C CA 2190732 C CA2190732 C CA 2190732C CA 002190732 A CA002190732 A CA 002190732A CA 2190732 A CA2190732 A CA 2190732A CA 2190732 C CA2190732 C CA 2190732C
Authority
CA
Canada
Prior art keywords
filter
absorbent matrix
blood
carbohydrate
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002190732A
Other languages
English (en)
Other versions
CA2190732A1 (fr
Inventor
Peggy Whitson
Vaughan Clift
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FIELDS EDEN E
TODD CHARLES H IV
TROELL MARTHA T
Original Assignee
FIELDS EDEN E
TODD CHARLES H IV
TROELL MARTHA T
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FIELDS EDEN E, TODD CHARLES H IV, TROELL MARTHA T filed Critical FIELDS EDEN E
Priority claimed from PCT/AU1995/000279 external-priority patent/WO1995031720A1/fr
Publication of CA2190732A1 publication Critical patent/CA2190732A1/fr
Application granted granted Critical
Publication of CA2190732C publication Critical patent/CA2190732C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5002—Partitioning blood components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Ecology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention concerne un appareil pour recueillir, séparer, analyser et conserver in situ de petites quantités de sang ou d'un autre fluide du corps. L'appareil comporte une chambre collectrice qui jouxte un filtre constitué d'une mince feuille d'un matériau fibreux dont les pores ont une taille moyenne inférieure à 3 microns. Le matériau fibreux a été traité par un mélange contenant 1-40 % en poids/volume d'hydrate de carbone et 0,1-15 % en poids/volume de protéine non spécifique. Un mélange préféré hdyrate de carbone/protéine est constitué par environ 10 % de mannitol et par environ 6 % d'albumine. Le sang ou autre fluide traverse la carte filtrante par effet de capillarité, aidé en cela par une matrice absorbante avec un facteur de Klemm élevé, jouxtant la carte filtrante. On peut traiter la matrice absorbante et/ou la carte filtrante avec différents réactifs de dosage/détection. La vitesse et l'efficacité du processus de séparation peuvent être modifiées (a) en changeant la concentration du mélange hydrate de carbone/protéine dans le mélange et/ou (b) en appliquant une pression sur un côté du filtre et/ou (c) en modifiant la densité relative et la taille des pores de la carte filtrante et de la matrice absorbante.
CA002190732A 1994-05-19 1995-05-15 Procede et appareil pour recueillir, conserver et analyser en temps reelle sang ou un autre fluide du corps Expired - Fee Related CA2190732C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24718794A 1994-05-19 1994-05-19
US08/247,187 1994-05-19
PCT/AU1995/000279 WO1995031720A1 (fr) 1994-05-15 1995-05-15 Procede et appareil pour recueillir, conserver et analyser en temps reel le sang ou un autre fluide du corps

Publications (2)

Publication Number Publication Date
CA2190732A1 CA2190732A1 (fr) 1995-11-23
CA2190732C true CA2190732C (fr) 2007-10-09

Family

ID=38596215

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002190732A Expired - Fee Related CA2190732C (fr) 1994-05-19 1995-05-15 Procede et appareil pour recueillir, conserver et analyser en temps reelle sang ou un autre fluide du corps

Country Status (1)

Country Link
CA (1) CA2190732C (fr)

Also Published As

Publication number Publication date
CA2190732A1 (fr) 1995-11-23

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