CA2191230C - Traitement d'affections intestinales inflammatoires faisant appel a une 2-halo-2'-desoxyadenosine - Google Patents
Traitement d'affections intestinales inflammatoires faisant appel a une 2-halo-2'-desoxyadenosine Download PDFInfo
- Publication number
- CA2191230C CA2191230C CA002191230A CA2191230A CA2191230C CA 2191230 C CA2191230 C CA 2191230C CA 002191230 A CA002191230 A CA 002191230A CA 2191230 A CA2191230 A CA 2191230A CA 2191230 C CA2191230 C CA 2191230C
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- 230000036642 wellbeing Effects 0.000 description 1
- -1 where Y is chloro Chemical compound 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
On décrit un traitement pour combattre les affections intestinales inflammatoires telles que la maladie de Crohn et la colite ulcéreuse. Ce traitement consiste à administrer à un humain ou à un mammifère atteint d'une telle affection une quantité, suffisante pour avoir un effet thérapeutique, d'une 2-halo-2'-désoxyadénosine.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1994/005971 WO1995032718A1 (fr) | 1994-05-26 | 1994-05-26 | Traitement d'affections intestinales inflammatoires faisant appel a une 2-halo-2'-desoxyadenosine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2191230A1 CA2191230A1 (fr) | 1995-12-07 |
| CA2191230C true CA2191230C (fr) | 2001-02-27 |
Family
ID=22242613
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002191230A Expired - Lifetime CA2191230C (fr) | 1994-05-26 | 1994-05-26 | Traitement d'affections intestinales inflammatoires faisant appel a une 2-halo-2'-desoxyadenosine |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPH10505323A (fr) |
| AU (1) | AU7470794A (fr) |
| CA (1) | CA2191230C (fr) |
| WO (1) | WO1995032718A1 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7528247B2 (en) | 2001-08-02 | 2009-05-05 | Genzyme Corporation | Process for preparing purine nucleosides |
| US7368423B1 (en) * | 2001-12-05 | 2008-05-06 | The Scripps Research Institute | Composition and method for treating chronic allograft rejection |
| EP1551386A4 (fr) * | 2002-09-27 | 2009-03-25 | Bioenvision Inc | Techniques et compositions destinees au traitement du lupus utilisant la clofarabine |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5310732A (en) * | 1986-02-03 | 1994-05-10 | The Scripps Research Institute | 2-halo-2'-deoxyadenosines in the treatment of rheumatoid arthritis |
| WO1989008658A1 (fr) * | 1988-03-16 | 1989-09-21 | Scripps Clinic And Research Foundation | Derives d'adenine substitues utiles en tant qu'agents therapeutiques |
-
1994
- 1994-05-26 AU AU74707/94A patent/AU7470794A/en not_active Abandoned
- 1994-05-26 WO PCT/US1994/005971 patent/WO1995032718A1/fr not_active Ceased
- 1994-05-26 JP JP8500782A patent/JPH10505323A/ja active Pending
- 1994-05-26 CA CA002191230A patent/CA2191230C/fr not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU7470794A (en) | 1995-12-21 |
| JPH10505323A (ja) | 1998-05-26 |
| CA2191230A1 (fr) | 1995-12-07 |
| WO1995032718A1 (fr) | 1995-12-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20140526 |