CA2193503C - Tensioactifs copolymeres blocs d'oxyde d'ethylene et d'oxyde de butylene utilises comme revetements stabilisants pour formulations nanocristallines - Google Patents

Tensioactifs copolymeres blocs d'oxyde d'ethylene et d'oxyde de butylene utilises comme revetements stabilisants pour formulations nanocristallines Download PDF

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Publication number
CA2193503C
CA2193503C CA002193503A CA2193503A CA2193503C CA 2193503 C CA2193503 C CA 2193503C CA 002193503 A CA002193503 A CA 002193503A CA 2193503 A CA2193503 A CA 2193503A CA 2193503 C CA2193503 C CA 2193503C
Authority
CA
Canada
Prior art keywords
ethylene oxide
surfactant
therapeutic
diagnostic
block copolymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002193503A
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English (en)
Other versions
CA2193503A1 (fr
Inventor
Sui Ming Wong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Perrigo Pharma International DAC
Original Assignee
Nanosystems LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/267,082 external-priority patent/US5587143A/en
Application filed by Nanosystems LLC filed Critical Nanosystems LLC
Publication of CA2193503A1 publication Critical patent/CA2193503A1/fr
Application granted granted Critical
Publication of CA2193503C publication Critical patent/CA2193503C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
CA002193503A 1994-06-28 1995-06-09 Tensioactifs copolymeres blocs d'oxyde d'ethylene et d'oxyde de butylene utilises comme revetements stabilisants pour formulations nanocristallines Expired - Fee Related CA2193503C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/267,082 1994-06-28
US08/267,082 US5587143A (en) 1994-06-28 1994-06-28 Butylene oxide-ethylene oxide block copolymer surfactants as stabilizer coatings for nanoparticle compositions
PCT/US1995/007406 WO1996000567A1 (fr) 1994-06-28 1995-06-09 Tensioactifs copolymeres blocs d'oxyde d'ethylene et d'oxyde de butylene utilises comme revetements stabilisants pour formulations nanocristallines

Publications (2)

Publication Number Publication Date
CA2193503A1 CA2193503A1 (fr) 1996-01-11
CA2193503C true CA2193503C (fr) 2006-08-08

Family

ID=36791727

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002193503A Expired - Fee Related CA2193503C (fr) 1994-06-28 1995-06-09 Tensioactifs copolymeres blocs d'oxyde d'ethylene et d'oxyde de butylene utilises comme revetements stabilisants pour formulations nanocristallines

Country Status (1)

Country Link
CA (1) CA2193503C (fr)

Also Published As

Publication number Publication date
CA2193503A1 (fr) 1996-01-11

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