CA2198667C - Composition contenant du 3-1-menthoxy propane 1, 2-diol, donnant une sensation rafraichissante - Google Patents

Composition contenant du 3-1-menthoxy propane 1, 2-diol, donnant une sensation rafraichissante Download PDF

Info

Publication number: CA2198667C
Authority: CA; Canada
Prior art keywords: composition; skin; diol; feet; cooling
Prior art date: 1996-02-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

CA 2198667

Other languages

English (en)

Other versions

CA2198667A1 (fr

Inventor

Atma Chaudhari

Erin Dunsmuir

Jennifer Smith

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Warner Lambert Co LLC

Original Assignee

Warner Lambert Co LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-02-28

Filing date

1997-02-27

Publication date

2006-01-10

1997-02-27 Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC

1997-08-28 Publication of CA2198667A1 publication Critical patent/CA2198667A1/fr

2006-01-10 Application granted granted Critical

2006-01-10 Publication of CA2198667C publication Critical patent/CA2198667C/fr

2017-02-27 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

239000000203 mixture Substances 0.000 title claims abstract description 78
MDVYIGJINBYKOM-UHFFFAOYSA-N 3-[[5-Methyl-2-(1-methylethyl)cyclohexyl]oxy]-1,2-propanediol Chemical compound CC(C)C1CCC(C)CC1OCC(O)CO MDVYIGJINBYKOM-UHFFFAOYSA-N 0.000 title claims abstract description 11
230000035597 cooling sensation Effects 0.000 title claims description 20
230000000699 topical effect Effects 0.000 claims abstract description 42
238000001816 cooling Methods 0.000 claims abstract description 13
239000004909 Moisturizer Substances 0.000 claims abstract description 8
238000000034 method Methods 0.000 claims abstract description 8
230000001333 moisturizer Effects 0.000 claims abstract description 8
239000003205 fragrance Substances 0.000 claims description 11
239000004615 ingredient Substances 0.000 claims description 5
NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims description 3
NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims description 3
239000001525 mentha piperita l. herb oil Substances 0.000 claims description 3
229940041616 menthol Drugs 0.000 claims description 3
235000019477 peppermint oil Nutrition 0.000 claims description 3
239000000341 volatile oil Substances 0.000 claims description 3
244000166124 Eucalyptus globulus Species 0.000 claims 1
206010033425 Pain in extremity Diseases 0.000 abstract description 4
SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-methylpentane-2,4-diol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 description 17
239000006210 lotion Substances 0.000 description 9
239000006071 cream Substances 0.000 description 8
239000000499 gel Substances 0.000 description 7
239000007788 liquid Substances 0.000 description 7
150000001875 compounds Chemical class 0.000 description 6
239000003906 humectant Substances 0.000 description 5
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
102000011782 Keratins Human genes 0.000 description 4
108010076876 Keratins Proteins 0.000 description 4
239000004902 Softening Agent Substances 0.000 description 4
239000003795 chemical substances by application Substances 0.000 description 4
239000003995 emulsifying agent Substances 0.000 description 4
BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 4
GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 4
QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 4
239000003381 stabilizer Substances 0.000 description 4
VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 3
239000004166 Lanolin Substances 0.000 description 3
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
235000021355 Stearic acid Nutrition 0.000 description 3
239000000443 aerosol Substances 0.000 description 3
239000002826 coolant Substances 0.000 description 3
229940039717 lanolin Drugs 0.000 description 3
235000019388 lanolin Nutrition 0.000 description 3
OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 3
239000003921 oil Substances 0.000 description 3
235000019198 oils Nutrition 0.000 description 3
239000003755 preservative agent Substances 0.000 description 3
-1 roll-on Substances 0.000 description 3
239000007921 spray Substances 0.000 description 3
239000008117 stearic acid Substances 0.000 description 3
239000002562 thickening agent Substances 0.000 description 3
LQIAZOCLNBBZQK-UHFFFAOYSA-N 1-(1,2-Diphosphanylethyl)pyrrolidin-2-one Chemical compound PCC(P)N1CCCC1=O LQIAZOCLNBBZQK-UHFFFAOYSA-N 0.000 description 2
QFOHBWFCKVYLES-UHFFFAOYSA-N Butylparaben Chemical compound CCCCOC(=O)C1=CC=C(O)C=C1 QFOHBWFCKVYLES-UHFFFAOYSA-N 0.000 description 2
208000003643 Callosities Diseases 0.000 description 2
FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 2
KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
206010020649 Hyperkeratosis Diseases 0.000 description 2
229920002125 Sokalan® Polymers 0.000 description 2
240000008042 Zea mays Species 0.000 description 2
235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 2
235000002017 Zea mays subsp mays Nutrition 0.000 description 2
POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
SNAAJJQQZSMGQD-UHFFFAOYSA-N aluminum magnesium Chemical compound [Mg].[Al] SNAAJJQQZSMGQD-UHFFFAOYSA-N 0.000 description 2
229960000541 cetyl alcohol Drugs 0.000 description 2
235000005822 corn Nutrition 0.000 description 2
238000010438 heat treatment Methods 0.000 description 2
JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
230000014759 maintenance of location Effects 0.000 description 2
LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 2
239000002480 mineral oil Substances 0.000 description 2
GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 description 2
239000000546 pharmaceutical excipient Substances 0.000 description 2
239000000419 plant extract Substances 0.000 description 2
229920001296 polysiloxane Polymers 0.000 description 2
239000000843 powder Substances 0.000 description 2
QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 2
239000008213 purified water Substances 0.000 description 2
239000000600 sorbitol Substances 0.000 description 2
PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 2
229910001220 stainless steel Inorganic materials 0.000 description 2
239000010935 stainless steel Substances 0.000 description 2
239000000230 xanthan gum Substances 0.000 description 2
235000010493 xanthan gum Nutrition 0.000 description 2
229920001285 xanthan gum Polymers 0.000 description 2
229940082509 xanthan gum Drugs 0.000 description 2
PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
WEEGYLXZBRQIMU-UHFFFAOYSA-N 1,8-cineole Natural products C1CC2CCC1(C)OC2(C)C WEEGYLXZBRQIMU-UHFFFAOYSA-N 0.000 description 1
ZKCZHZHXSQGGDC-UHFFFAOYSA-N 1-(5-methyl-2-propan-2-ylcyclohexyl)oxypropane-1,2-diol Chemical compound CC(C)C1CCC(C)CC1OC(O)C(C)O ZKCZHZHXSQGGDC-UHFFFAOYSA-N 0.000 description 1
HXPKUOKFSVGGHB-UHFFFAOYSA-N 1-methyl-4-propan-2-yl-1-propoxycyclohexane Chemical compound CCCOC1(C)CCC(C(C)C)CC1 HXPKUOKFSVGGHB-UHFFFAOYSA-N 0.000 description 1
FKOKUHFZNIUSLW-UHFFFAOYSA-N 2-Hydroxypropyl stearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(C)O FKOKUHFZNIUSLW-UHFFFAOYSA-N 0.000 description 1
SHDIPWPAGQDYTH-UHFFFAOYSA-N 2-[bis(2-hydroxyethyl)amino]ethanol;prop-2-enoic acid Chemical compound OC(=O)C=C.OCCN(CCO)CCO SHDIPWPAGQDYTH-UHFFFAOYSA-N 0.000 description 1
QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 1
DISYHRKLFBBFAS-UHFFFAOYSA-N 3-(1-methyl-4-propan-2-ylcyclohexyl)oxypropane-1,2-diol Chemical compound CC(C)C1CCC(C)(OCC(O)CO)CC1 DISYHRKLFBBFAS-UHFFFAOYSA-N 0.000 description 1
NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 1
244000144927 Aloe barbadensis Species 0.000 description 1
235000002961 Aloe barbadensis Nutrition 0.000 description 1
240000000560 Citrus x paradisi Species 0.000 description 1
206010013911 Dysgeusia Diseases 0.000 description 1
WEEGYLXZBRQIMU-WAAGHKOSSA-N Eucalyptol Chemical compound C1C[C@H]2CC[C@]1(C)OC2(C)C WEEGYLXZBRQIMU-WAAGHKOSSA-N 0.000 description 1
244000004281 Eucalyptus maculata Species 0.000 description 1
241000208152 Geranium Species 0.000 description 1
SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 1
229920002907 Guar gum Polymers 0.000 description 1
244000178870 Lavandula angustifolia Species 0.000 description 1
235000010663 Lavandula angustifolia Nutrition 0.000 description 1
244000246386 Mentha pulegium Species 0.000 description 1
235000016257 Mentha pulegium Nutrition 0.000 description 1
235000004357 Mentha x piperita Nutrition 0.000 description 1
241000282320 Panthera leo Species 0.000 description 1
239000004264 Petrolatum Substances 0.000 description 1
240000002505 Pogostemon cablin Species 0.000 description 1
235000011751 Pogostemon cablin Nutrition 0.000 description 1
239000002202 Polyethylene glycol Substances 0.000 description 1
244000086363 Pterocarpus indicus Species 0.000 description 1
235000009984 Pterocarpus indicus Nutrition 0.000 description 1
244000178231 Rosmarinus officinalis Species 0.000 description 1
GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
229960000458 allantoin Drugs 0.000 description 1
235000011399 aloe vera Nutrition 0.000 description 1
150000001413 amino acids Chemical class 0.000 description 1
230000003444 anaesthetic effect Effects 0.000 description 1
229940067596 butylparaben Drugs 0.000 description 1
239000004202 carbamide Substances 0.000 description 1
229960001631 carbomer Drugs 0.000 description 1
229940112822 chewing gum Drugs 0.000 description 1
235000015218 chewing gum Nutrition 0.000 description 1
229960005233 cineole Drugs 0.000 description 1
229920001577 copolymer Polymers 0.000 description 1
SOROIESOUPGGFO-UHFFFAOYSA-N diazolidinylurea Chemical compound OCNC(=O)N(CO)C1N(CO)C(=O)N(CO)C1=O SOROIESOUPGGFO-UHFFFAOYSA-N 0.000 description 1
229960001083 diazolidinylurea Drugs 0.000 description 1
229940124274 edetate disodium Drugs 0.000 description 1
230000000694 effects Effects 0.000 description 1
229960001617 ethyl hydroxybenzoate Drugs 0.000 description 1
235000010228 ethyl p-hydroxybenzoate Nutrition 0.000 description 1
239000004403 ethyl p-hydroxybenzoate Substances 0.000 description 1
NUVBSKCKDOMJSU-UHFFFAOYSA-N ethylparaben Chemical compound CCOC(=O)C1=CC=C(O)C=C1 NUVBSKCKDOMJSU-UHFFFAOYSA-N 0.000 description 1
239000010642 eucalyptus oil Substances 0.000 description 1
229940044949 eucalyptus oil Drugs 0.000 description 1
238000011156 evaluation Methods 0.000 description 1
150000002191 fatty alcohols Chemical class 0.000 description 1
150000002194 fatty esters Chemical class 0.000 description 1
235000011187 glycerol Nutrition 0.000 description 1
229940075507 glyceryl monostearate Drugs 0.000 description 1
239000000665 guar gum Substances 0.000 description 1
235000010417 guar gum Nutrition 0.000 description 1
229960002154 guar gum Drugs 0.000 description 1
229940051250 hexylene glycol Drugs 0.000 description 1
235000001050 hortel pimenta Nutrition 0.000 description 1
235000014655 lactic acid Nutrition 0.000 description 1
239000004310 lactic acid Substances 0.000 description 1
239000001102 lavandula vera Substances 0.000 description 1
235000018219 lavender Nutrition 0.000 description 1
230000005923 long-lasting effect Effects 0.000 description 1
239000000314 lubricant Substances 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
239000000463 material Substances 0.000 description 1
229920000609 methyl cellulose Polymers 0.000 description 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
235000010270 methyl p-hydroxybenzoate Nutrition 0.000 description 1
239000004292 methyl p-hydroxybenzoate Substances 0.000 description 1
239000001923 methylcellulose Substances 0.000 description 1
229960002216 methylparaben Drugs 0.000 description 1
235000010446 mineral oil Nutrition 0.000 description 1
239000001788 mono and diglycerides of fatty acids Substances 0.000 description 1
JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 1
230000000399 orthopedic effect Effects 0.000 description 1
239000002304 perfume Substances 0.000 description 1
229940066842 petrolatum Drugs 0.000 description 1
235000019271 petrolatum Nutrition 0.000 description 1
229960005323 phenoxyethanol Drugs 0.000 description 1
230000037081 physical activity Effects 0.000 description 1
229920001223 polyethylene glycol Polymers 0.000 description 1
235000010232 propyl p-hydroxybenzoate Nutrition 0.000 description 1
239000004405 propyl p-hydroxybenzoate Substances 0.000 description 1
229960004063 propylene glycol Drugs 0.000 description 1
235000013772 propylene glycol Nutrition 0.000 description 1
229940093625 propylene glycol monostearate Drugs 0.000 description 1
229960003415 propylparaben Drugs 0.000 description 1
239000008262 pumice Substances 0.000 description 1
235000011803 sesame oil Nutrition 0.000 description 1
239000008159 sesame oil Substances 0.000 description 1
229940032094 squalane Drugs 0.000 description 1
239000004575 stone Substances 0.000 description 1
239000000126 substance Substances 0.000 description 1
238000002560 therapeutic procedure Methods 0.000 description 1
150000003626 triacylglycerols Chemical class 0.000 description 1
229960004418 trolamine Drugs 0.000 description 1
235000015112 vegetable and seed oil Nutrition 0.000 description 1
239000008158 vegetable oil Substances 0.000 description 1

Landscapes

Cosmetics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

CA 2198667 1996-02-28 1997-02-27 Composition contenant du 3-1-menthoxy propane 1, 2-diol, donnant une sensation rafraichissante Expired - Fee Related CA2198667C (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US1243396P	1996-02-28	1996-02-28
US60/012,433		1996-02-28

Publications (2)

Publication Number	Publication Date
CA2198667A1 CA2198667A1 (fr)	1997-08-28
CA2198667C true CA2198667C (fr)	2006-01-10

Family

ID=21754958

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA 2198667 Expired - Fee Related CA2198667C (fr)	1996-02-28	1997-02-27	Composition contenant du 3-1-menthoxy propane 1, 2-diol, donnant une sensation rafraichissante

Country Status (1)

Country	Link
CA (1)	CA2198667C (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2008195710A (ja) *	2007-01-17	2008-08-28	Takasago Internatl Corp	保湿組成物

1997
- 1997-02-27 CA CA 2198667 patent/CA2198667C/fr not_active Expired - Fee Related

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2008195710A (ja) *	2007-01-17	2008-08-28	Takasago Internatl Corp	保湿組成物
EP1946743A3 (fr) *	2007-01-17	2011-04-06	Takasago International Corporation	Composition humectante

Also Published As

Publication number	Publication date
CA2198667A1 (fr)	1997-08-28

Legal Events

Date	Code	Title	Description
2001-12-13	EEER	Examination request
2009-02-27	MKLA	Lapsed

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