CA2198729A1 - Nouvel homologue de la kinase humaine activee par un mitogene (map) - Google Patents
Nouvel homologue de la kinase humaine activee par un mitogene (map)Info
- Publication number
- CA2198729A1 CA2198729A1 CA002198729A CA2198729A CA2198729A1 CA 2198729 A1 CA2198729 A1 CA 2198729A1 CA 002198729 A CA002198729 A CA 002198729A CA 2198729 A CA2198729 A CA 2198729A CA 2198729 A1 CA2198729 A1 CA 2198729A1
- Authority
- CA
- Canada
- Prior art keywords
- smap
- polypeptide
- leu
- sequence
- expression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 210000005253 yeast cell Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Rheumatology (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
L'invention concerne des séquences d'acides nucléiques et d'acides aminés qui identifient et codent un nouvel homologue de la kinase humaine activée par un mitogène (SMAP), exprimée par des cellules stomacales humaines. L'invention concerne également des oligomères pour PCR ou des sondes pour hydridation permettant la détection de séquences nucléotidiques codant pour des molécules de SMAP ou analogue, des molécules antisens par rapport aux séquences nucléotidiques codant SMAP, des tests de diagnostic basés sur des molécules d'acide nucléique codant SMAP, des vecteurs d'expression obtenus par génie génétique et des cellules hôtes pour la production de SMAP purifiée, des anticorps capables de se lier spécifiquement à SMAP purifiée, des anticorps capables de se lier spécifiquement à SMAP, ainsi que des agonistes et des inhibiteurs capables de se fixer d'une manière spécifique au polypeptide SMAP.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72295P | 1995-06-30 | 1995-06-30 | |
| US60/000,722 | 1995-06-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2198729A1 true CA2198729A1 (fr) | 1997-01-23 |
Family
ID=21692739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002198729A Abandoned CA2198729A1 (fr) | 1995-06-30 | 1996-06-28 | Nouvel homologue de la kinase humaine activee par un mitogene (map) |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0781336A1 (fr) |
| JP (1) | JPH10505510A (fr) |
| AU (1) | AU723640B2 (fr) |
| CA (1) | CA2198729A1 (fr) |
| MX (1) | MX9701596A (fr) |
| WO (1) | WO1997002347A1 (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5869043A (en) * | 1993-09-17 | 1999-02-09 | Smithkline Beecham Corporation | Drug binding protein |
| EP0932666B1 (fr) * | 1996-10-09 | 2004-12-15 | Medical Research Council | Proteine kinases activees par les mitogenes, polypeptides, polynucleotides et leur utilisation |
| CA2223075A1 (fr) * | 1997-12-02 | 1999-06-02 | Smithkline Beecham Corporation | Proteine fixatrice de medicaments |
| US6897019B1 (en) | 1998-04-17 | 2005-05-24 | Tufts College | Methods for treating and preventing insulin resistance and related disorders |
| WO2000006728A2 (fr) * | 1998-07-28 | 2000-02-10 | Incyte Pharmaceuticals, Inc. | Effecteurs de phosphorylation |
| US8900811B2 (en) | 2000-11-16 | 2014-12-02 | Caliper Life Sciences, Inc. | Method and apparatus for generating thermal melting curves in a microfluidic device |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994023039A1 (fr) * | 1993-04-07 | 1994-10-13 | The Institute Of Cancer Research: Royal Cancer Hospital | Procedes de criblage de substances a activite therapeutique et levure utilisee a cet effet |
-
1996
- 1996-06-28 JP JP9505271A patent/JPH10505510A/ja not_active Withdrawn
- 1996-06-28 WO PCT/US1996/011170 patent/WO1997002347A1/fr not_active Ceased
- 1996-06-28 CA CA002198729A patent/CA2198729A1/fr not_active Abandoned
- 1996-06-28 MX MX9701596A patent/MX9701596A/es unknown
- 1996-06-28 EP EP96923586A patent/EP0781336A1/fr not_active Withdrawn
- 1996-06-28 AU AU64059/96A patent/AU723640B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997002347A1 (fr) | 1997-01-23 |
| AU723640B2 (en) | 2000-08-31 |
| JPH10505510A (ja) | 1998-06-02 |
| MX9701596A (es) | 1997-05-31 |
| AU6405996A (en) | 1997-02-05 |
| EP0781336A1 (fr) | 1997-07-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Dead |