CA2199149A1 - Modulation directe et indirecte des variations spectrophotometriques dans une couche lipidique utilisee pour mesurer des analytes - Google Patents

Modulation directe et indirecte des variations spectrophotometriques dans une couche lipidique utilisee pour mesurer des analytes

Info

Publication number
CA2199149A1
CA2199149A1 CA 2199149 CA2199149A CA2199149A1 CA 2199149 A1 CA2199149 A1 CA 2199149A1 CA 2199149 CA2199149 CA 2199149 CA 2199149 A CA2199149 A CA 2199149A CA 2199149 A1 CA2199149 A1 CA 2199149A1
Authority
CA
Canada
Prior art keywords
binding
change
polymerized
analyte
layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2199149
Other languages
English (en)
Inventor
Hans O. Ribi
Ben Liu
Herman Gaub
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biocircuits Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2199149A1 publication Critical patent/CA2199149A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/586—Liposomes, microcapsules or cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Structures Or Materials For Encapsulating Or Coating Semiconductor Devices Or Solid State Devices (AREA)
  • Encapsulation Of And Coatings For Semiconductor Or Solid State Devices (AREA)
  • Lead Frames For Integrated Circuits (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

L'invention concerne des procédés de détection d'un analyte, impliquant la liaison d'un ligand (analyte ou élément mimétique d'un analyte) à un élément de liaison réciproque, et dans lesquels le décalage chromatique résultant de la liaison du ligand à une couche polymérisée est mesuré; ou l'effet de la liaison du ligand sur le décalage chromatique produit par une modification de l'environnement de la couche polymérisée est mesuré. Les variations de température ou de pH, ou d'autres mécanismes déclenchant une modification optique dans le polymère, entraînent un décalage chromatique. Il est démontré que la liaison d'un analyte à un ligand lié à la couche polymérisée module le décalage chromatique résultant de la variation de la température ou du pH, ou d'autres mécanismes susceptibles de déclencher une modification optique des propriétés chromatiques du polymère.
CA 2199149 1994-09-13 1995-09-12 Modulation directe et indirecte des variations spectrophotometriques dans une couche lipidique utilisee pour mesurer des analytes Abandoned CA2199149A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30508894A 1994-09-13 1994-09-13
US08/305,088 1994-09-13

Publications (1)

Publication Number Publication Date
CA2199149A1 true CA2199149A1 (fr) 1996-03-21

Family

ID=23179276

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2199149 Abandoned CA2199149A1 (fr) 1994-09-13 1995-09-12 Modulation directe et indirecte des variations spectrophotometriques dans une couche lipidique utilisee pour mesurer des analytes

Country Status (4)

Country Link
EP (1) EP0781413A1 (fr)
JP (1) JPH10505904A (fr)
CA (1) CA2199149A1 (fr)
WO (1) WO1996008721A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU714839B2 (en) * 1995-02-13 2000-01-13 Regents Of The University Of California, The Three-dimensional colorimetric assay assemblies
EP1112377A4 (fr) * 1998-06-22 2004-11-10 Univ California Detecteurs colorimetriques de substances a analyser couples a des acides nucleiques
CA2286414A1 (fr) * 1999-10-04 2001-04-04 Zhibo Gan Dosage heterogene et sans separation de substances biologiques
SE0201468D0 (sv) * 2002-05-13 2002-05-13 Peter Aasberg Metod att använda luminescenta polymerer för detektion av biospecifik växelverkan
US6963007B2 (en) 2002-12-19 2005-11-08 3M Innovative Properties Company Diacetylenic materials for sensing applications

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4489133A (en) * 1982-11-16 1984-12-18 The Board Of Trustees Of The Leland Stanford Jr. University Two-dimensional crystallization technique
US5268305A (en) * 1989-06-15 1993-12-07 Biocircuits Corporation Multi-optical detection system
US5156810A (en) * 1989-06-15 1992-10-20 Biocircuits Corporation Biosensors employing electrical, optical and mechanical signals
US5399486A (en) * 1993-02-18 1995-03-21 Biocircuits Corporation Disposable unit in diagnostic assays
US5415999A (en) * 1993-07-09 1995-05-16 Biocircuits Corporation Fluorescent lipid polymer-macromolecular ligand compositions as detection element in ligand assays

Also Published As

Publication number Publication date
JPH10505904A (ja) 1998-06-09
WO1996008721A1 (fr) 1996-03-21
EP0781413A1 (fr) 1997-07-02

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