CA2199964A1 - 6-aryle pyrido[2,3-d]pyrimidines et naphtyridines destinees a l'inhibition de la proliferation cellulaire induite par proteine tyrosine kinase - Google Patents
6-aryle pyrido[2,3-d]pyrimidines et naphtyridines destinees a l'inhibition de la proliferation cellulaire induite par proteine tyrosine kinaseInfo
- Publication number
- CA2199964A1 CA2199964A1 CA 2199964 CA2199964A CA2199964A1 CA 2199964 A1 CA2199964 A1 CA 2199964A1 CA 2199964 CA2199964 CA 2199964 CA 2199964 A CA2199964 A CA 2199964A CA 2199964 A1 CA2199964 A1 CA 2199964A1
- Authority
- CA
- Canada
- Prior art keywords
- pyrido
- pyrimidin
- dichlorophenyl
- urea
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 229940121358 tyrosine kinase inhibitor Drugs 0.000 description 1
- 108091005990 tyrosine-phosphorylated proteins Proteins 0.000 description 1
- 125000001493 tyrosinyl group Chemical group [H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 description 1
- 150000003672 ureas Chemical class 0.000 description 1
- 208000010570 urinary bladder carcinoma Diseases 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 239000011345 viscous material Substances 0.000 description 1
- 239000011534 wash buffer Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 239000003871 white petrolatum Substances 0.000 description 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Les 6-aryle pyrido[2,3-d]pyrimidines et les naphtyridines sont des inhibiteurs de la protéine tyrosine kinase, et conviennent ainsi au traitement de la prolifération cellulaire induite par cette dernière. Ces composés conviennent particulièrement au traitement de l'athérosclérose, de la resténose, du psoriasis, ainsi que des infections bactériennes.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US339,051 | 1989-04-14 | ||
| US39905194A | 1994-11-14 | 1994-11-14 | |
| US539,410 | 1995-11-06 | ||
| US08/539,410 US5733913A (en) | 1994-11-14 | 1995-11-06 | 6-Aryl pyrido 2,3-d! pyrimidines and naphthyridines for inhibiting protein tyrosine kinase mediated cellular proliferation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2199964A1 true CA2199964A1 (fr) | 1996-05-23 |
Family
ID=27016478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2199964 Abandoned CA2199964A1 (fr) | 1994-11-14 | 1995-11-13 | 6-aryle pyrido[2,3-d]pyrimidines et naphtyridines destinees a l'inhibition de la proliferation cellulaire induite par proteine tyrosine kinase |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2199964A1 (fr) |
-
1995
- 1995-11-13 CA CA 2199964 patent/CA2199964A1/fr not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Dead |