CA2201588A1 - Proteines de recombinaison d'une souche pakistanaise d'hepatite e et leur utilisation dans des procedes de diagnostic et des vaccins - Google Patents

Proteines de recombinaison d'une souche pakistanaise d'hepatite e et leur utilisation dans des procedes de diagnostic et des vaccins

Info

Publication number
CA2201588A1
CA2201588A1 CA 2201588 CA2201588A CA2201588A1 CA 2201588 A1 CA2201588 A1 CA 2201588A1 CA 2201588 CA2201588 CA 2201588 CA 2201588 A CA2201588 A CA 2201588A CA 2201588 A1 CA2201588 A1 CA 2201588A1
Authority
CA
Canada
Prior art keywords
hev
protein
hepatitis
ala
leu
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2201588
Other languages
English (en)
Inventor
Sergei A. Tsarev
Suzanne U. Emerson
Robert H. Purcell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/316,765 external-priority patent/US6706873B1/en
Application filed by Individual filed Critical Individual
Priority claimed from PCT/US1995/013102 external-priority patent/WO1996010580A2/fr
Publication of CA2201588A1 publication Critical patent/CA2201588A1/fr
Abandoned legal-status Critical Current

Links

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  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention se rapporte à une souche du virus de l'hépatite E provenant du Pakistan (SAR-55) impliquée dans une épidémie d'hépatite non A, non B transmise de manière entérique, et appelée aujourd'hui hépatite E. L'invention se rapporte en outre à l'expression de toute la région structurale de SAR-55, nommée cadre de lecture ouvert 2 (ORF-2), dans un système d'expression eucaryotique. La protéine exprimée est capable de former des particules analogues au virus VHE (virus de l'hépatite E) qui peuvent être utilisées comme antigènes dans des essais immunologiques de diagnostic, et comme immunogènes ou vaccins destinés à protéger contre des infections dues à l'hépatite E.
CA 2201588 1994-10-03 1995-10-03 Proteines de recombinaison d'une souche pakistanaise d'hepatite e et leur utilisation dans des procedes de diagnostic et des vaccins Abandoned CA2201588A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/316,765 US6706873B1 (en) 1992-09-18 1994-10-03 Recombinant proteins of a pakistani strain of hepatitis E and their use in diagnostic methods and vaccines
US08/316,765 1994-10-03
PCT/US1995/013102 WO1996010580A2 (fr) 1994-10-03 1995-10-03 Proteines de recombinaison d'une souche pakistanaise d'hepatite e et leur utilisation dans des procedes de diagnostic et des vaccins

Publications (1)

Publication Number Publication Date
CA2201588A1 true CA2201588A1 (fr) 1996-04-11

Family

ID=29405777

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2201588 Abandoned CA2201588A1 (fr) 1994-10-03 1995-10-03 Proteines de recombinaison d'une souche pakistanaise d'hepatite e et leur utilisation dans des procedes de diagnostic et des vaccins

Country Status (1)

Country Link
CA (1) CA2201588A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112724205A (zh) * 2021-02-01 2021-04-30 山西省中医药研究院(山西省中医院) C种戊型肝炎病毒239蛋白制备病毒样颗粒的方法和应用

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112724205A (zh) * 2021-02-01 2021-04-30 山西省中医药研究院(山西省中医院) C种戊型肝炎病毒239蛋白制备病毒样颗粒的方法和应用
CN112724205B (zh) * 2021-02-01 2023-05-02 山西省中医药研究院(山西省中医院) C种戊型肝炎病毒239蛋白制备病毒样颗粒的方法和应用

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